CAS: 171263-26-6; 2-((S)-1-((2S,5S,11S)-5,11-Diisopropyl-2-Methyl-4,7,10,13-Tetraoxo-3,6,9,12-Tetraazaoctacosan-1-Oyl)Pyrrolidine-2-Carboxamido)Acetic Acid

该化合物是一种合成浸泡物,由与六氯化萘序列相融合的棕榈酸链组成,其用意是提高皮肤屏障功能,通过调制细胞通信和科洛拉根合成促进肾上腺修复,其亲脂性可以改善皮肤渗透,允许有针对性地交付和持续活动.研究显示,它可以通过刺激外细胞基质成分来支持皮肤弹性和减少细线的外形.该化合物在配方中保持稳定,并与各种化妆品交付系统相容.其机制涉及与与皮肤软体常态有关的关键受体进行互动,使其成为皮肤学和反细胞学应用的功能成分.

结构式图片

合成工艺路线路线简述

    专利信息


    专利号:EP-1721601-A1
    优先权日:2005-05-11
    标 题 :Use of taurine for enhancing lipid synthesis in the epidermis
    发明人:DOERING THOMAS; WALDMANN-LAUE MARIANNE; WADLE ARMIN; ANDERHEGGEN BERND
    权利人:HENKEL KGAA
    摘要:The present invention is the use of taurine for stimulating the epidermal synthesis of barrier lipids.

    专利号:US-2006217788-A1
    优先权日:2004-07-09
    标 题:Method of using laser induced injury to activate topical prodrugs
    发明人:HERRON G S; BOMMANNAN D B
    权利人:HERRON G S; BOMMANNAN D B
    摘要:Methods and compositions are disclosed for improving the wound healing process and increasing collagen synthesis following laser induced thermal injury. The method comprises delivering prodrugs to a target site before the target site is injured and taking advantage of those enzymes that are physiologically-expressed to promote wound healing to convert the prodrugs to active drugs. The claimed invention has the advantage of the prodrugs being readily available to immediately participate in the wound healing process, but not have any negative side-effects of the active drug being present before injury occurs.

    专利号:WO-2006053688-A1
    优先权日:2004-11-17
    标 题:Cosmetic and dermatological preparations for the treatment of mature skin
    发明人:DOERING THOMAS
    权利人:HENKEL KGAA; DOERING THOMAS
    摘要:The invention relates to topical cosmetic or dermatological compositions for the treatment of mature or intrinsically or extrinsically aged skin, in particular, for anti-wrinkle treatment, containing a combination of at least two selected peptides in a suitable cosmetic or dermatological vehicle, which have an effect at differing points of the process of collagen and/or fibronectin synthesis.

    专利号:WO-2006042625-A2
    优先权日:2004-10-15
    标 题 :Compositions with inhibitors of the synthesis of prostaglandin and/or of leukotriene in conjunction with stimulators of the release of cutaneous neuromediators

    专利号:EP-1799311-A2
    优先权日:2004-10-15
    标 题:Compositions with inhibitors of the synthesis of prostaglandin and/or of leukotriene in conjunction with stimulators of the release of cutaneous neuromediators

    专利号:US-8361516-B2
    优先权日:2006-08-03
    标 题:Composition comprising sarsasapogenin
    发明人:LINTNER KARL; MAS CHAMBERLIN CLAIRE
    权利人:SEDERMA SA; LINTNER KARL; MAS CHAMBERLIN CLAIRE
    摘要:The présent invention relates to a composition comprising sarsasapogenin or a plant extract containing it in order to improve the gêneral state of the skin and in particular to improve and/or embellish any part of the body showing a déficit in lipids. More particularly, the invention is directed to a cosmetic method to improve the figure, comprising the step of topically applying to the skin a cosmetic or dermopharmaceutical composition comprising sarsasapogenin to favour the expansion and/or the formation of the subcutaneous adipose tissue, and/or to favour the lipid synthesis in the epidermis.
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    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Final Report 06/10/2014 Available from CIR
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