CAS: 6635-20-7; 4-Hydroxy-3-Methoxy-5-Nitrobenzaldehyde

上下游产品

CAS号121-33-5 香草醛 | CAS号51673-97-3 4-hydroxy-3-met... | CAS号37987-22-7 4-(hydroxymethy... | CAS号859932-59-5 5-formyl-2-hydr... | CAS号498-00-0 香草醇 | CAS号7697-37-2 硝酸 | CAS号60-29-7 乙醚 | CAS号7782-77-6 亚硝酸 | CAS号67-64-1 丙酮 | CAS号56-23-5 四氯化碳 | CAS号146698-91-1 (E/Z)-3-O-Methy... | CAS号141206-79-3 2-(4-chloro-3-m... | CAS号857629-78-8 (E)-3-O-Methyl ... | CAS号158693-04-0 (Z)-N,N-diethyl... | CAS号1021493-52-6 TRIFLUORO-METHA... | CAS号130929-57-6 恩他卡朋 | CAS号116313-85-0 3,4-二羟基-5-硝基苯甲醛 | CAS号312327-13-2 3-苄氧基-4-羟基-5-硝基-苯甲醛 | CAS号312731-70-7 三氟-甲烷磺酸2-苄氧基-4-... | CAS号15785-54-3 5-硝基香草酸

香草醛置于yttrium(Lll) Nitrate Hexahydrate体系中,用 溶剂黄146 作为反应溶剂,化学反应 0.17H,以87%的收率获得产物5-硝基香兰素
参考文献:硝酸乙酸在室温下在硝酸乙酸中介导的苯酚硝化
标题:硝酸乙酸在室温下在硝酸乙酸中介导的苯酚硝化
摘要:观测到在室温下在冰醋酸中使用y(no 3)3 .6H2O快速硝化富电子酚的产率.该方法允许硝化酚而不氧化,并且以快速和简单的方式分离硝化产物.所描述的方法对苯酚具有选择性. 已经观测到在室温下在冰醋酸中使用y(no 3)3 .6H2O方便且容易地硝化芳族酚.该方法非常简单,快速并且对酚类具有特异性.
DOI:10.1007/s12039-016-1202-1

专利信息

专利号:EP-1383732-B1
优先权日:2001-05-04
标题:Labelling reagents, method for synthesis of said reagents and methods for detecting biological molecules
发明人：BOURGET CECILE; LHOMME JEAN; LAAYOUN ALI; KOTERA MITSUHARU; TREVISIOL EMMANUELLE; MENOU LIONEL; BERNAL MENDEZ ELOY
权利人:BIO MERIEUX; UNIV GRENOBLE 1; CENTRE NAT RECH SCIENT
摘要:The invention concerns a temperature-stable labelling reagent of formula (I), wherein: R<1> represents H or an alkyl, aryl or substituted aryl group; R<2> represents a detectable marker or at least two detectable markers linked together by at least a multimeric structure; L is a linking arm comprising a linear catemer concatenation of at least two covalent bonds; and n is an integer equal to 0 or 1; R<3> and R<4> represent, independently of each other: H, NO2, Cl, Br, F, I, R<2>-(L)n-Y-X-, OR, SR, NR2, R, NHCOR, CONHR, COOR with R = alkyl or aryl, A is a linking arm comprising at least a double bond enabling the conjugation of the diazo function with the aromatic cycle; and u is a whole number between 0 and 2, preferably between 0 and 1; and -Y-X- represents -CONH-, -NHCO-, -CH2O-, -CH2S-. The invention also concerns a method for the synthesis of said markers and uses for labelling biological molecules, in particular nucleic acids, with a labelling reagent bearing the diazomethyl function. The invention is particularly applicable in the field of diagnosis.

专利号:US-2018370958-A1
优先权日:2017-06-27
标题:Route Of Synthesis For Opicapone
发明人：NABOLD CHRISTIAN FRECH; AEBERSOLD CHRISTINE; GRIECO PASQUALE GABRIELE; AESCHBACHER ROMAN GERBER
权利人:AZAD PHARMACEUTICAL INGREDIENTS AG
摘要:The present invention relates to a new route of synthesis for obtaining Opicapone ((4Z)-4-[3-(2,5-dichloro-4,6-dimethyl-1-oxidopyridin-1-ium-3-yl)-2H-1,2,4-oxadia-zol-5-ylidene]-2-hydroxy-6-nitrocyclohexa-2,5-dien-1-one), new intermediates in the reaction path and the new substance 2,5-dichloro-N-hydroxy-4,6-dimethylpyridine-3-carboximidoyl chloride.

专利号:CA-2444918-C
优先权日:2001-05-04
标 题:Labelling reagents, method for synthesis of said reagents and methods for detecting biological molecules

专利号:CN-1518536-A
优先权日:2001-05-04
标 题 :Labelling reagents, method for synthesis of said reagents and methods for detecting biological molecules

专利号:EP-1383732-A1
优先权日:2001-05-04
标 题:Labelling reagents, method for synthesis of said reagents and methods for detecting biological molecules

专利号:US-6417195-B1
优先权日:1999-02-22
标题 :Isoquinoline derivatives and isoquinoline combinatorial libraries
发明人：LEBL MICHAL
权利人:LION BIOSCIENCE AG
摘要:The present invention provides the synthesis of heterocyclic compounds based on the isoquinoline ring. More specifically, the invention provides novel isoquinoline derivatives as well as novel libraries comprised of such compounds.