CAS: 81353-38-0; Trimethyl((Tributylstannyl)Ethynyl)Silane

该化合物是有机锡化合物,其特点是三甲基硅酸盐组和三丁基锡基的乙烯功能组的存在,这种复合物一般具有高度的稳定性,因为具有有机锡化合物特征的坚固的锡-碳结壳具有高度稳定性,经常用于有机合成和材料科学,特别是聚合物的开发,并用作各种化学反应的试剂.三甲基硅基锡化合物组的存在提高了有机溶剂的溶性,使其在需要与有机基体兼容的用途中有用.此外,苯乙烯组可以参与进一步的化学反应,例如交叉反应,从而可以形成更为复杂的结构.然而,与许多有机锡化合物一样,它可能对环境和健康造成危害,需要根据安全条例谨慎地处理和处置.

结构式图片

相似化合物

994-89-8 64099-82-7

物理性质

MSDS等安全信息

欧盟法规

C&L通报

上下游产品

CAS号1461-22-9 三丁基氯化锡 | CAS号1066-54-2 三甲基硅基乙炔 | CAS号1067-52-3 三正丁基甲氧基锡 | CAS号6224-91-5 1-(三甲基硅基)丙炔 | CAS号3989-14-8 [(4-甲氧基苯基)乙炔基]三甲基硅烷 | CAS号813-19-4 六丁基锡 | CAS号78704-49-1 (4-氯苯炔基)三甲基硅烷 | CAS号133826-69-4 trimethyl-[2-[6... | CAS号2170-06-1 1-苯基-2-(三甲基硅)乙炔 | CAS号13829-77-1 Phenyl(trimethy... | CAS号75867-38-8 三甲基((4-硝基苯基)乙炔基)硅烷 | CAS号99048-48-3 1-(4-methoxyphe... | CAS号55682-48-9 1,6-脱水-2-叠氮-2-脱...

合成工艺路线路线简述

  • 1461-22-9 + 1066-54-2 = 81353-38-0
    反应条件:1.1 Reagents: Butyllithium Solvents: Tetrahydrofuran,Hexane; < -70 °C; Rt; 1 H,Rt; Rt -> 0 °C1.2 15 Min,0 °C; 0 °C -> Rt; 16 H,Rt1.3 Reagents: Water
    标题:Phosphine-Free Stille-Migita Chemistry For The Mild And Orthogonal Modification Of Dna And Rna
    作者:Krause,Andre; Et Al
    参考文献:Chemistry - A European Journal 日期:2014 卷标:20(50) 页码:16613-16619]

    1066-54-2 = 81353-38-0
    反应条件:1.1 Catalysts: Ruthenium(1+),[(1′,2′,3′,4′,5′,6′-η)-2,2′′,4,4′′,6,6′′-Hexamethyl[1,1′:3′,1′′-T... Solvents: Dichloromethane; 24 H,30 °C1.2 Reagents: Triethylamine Solvents: Pentane
    标题:Catalytic Dehydrogenative Stannylation Of C(Sp)-H Bonds Involving Cooperative Sn-H Bond Activation Of Hydrostannanes
    作者:Forster,Francis; Et Al
    参考文献:Journal Of The American Chemical Society 日期:2018 卷标:140(4) 页码:1259-1262]

    682-00-8 = 81353-38-0
    反应条件:1.1 Solvents: Tetrahydrofuran
    标题:Transmetalation From Zirconium To Tin: A Facile Preparation Of Organostannanes From Organozirconiums
    作者:Kim,Sunggak; Et Al
    参考文献:Tetrahedron Letters 日期:1995 卷标:36(21) 页码:3725-8]

    14630-40-1 = 81353-38-0 [标题:Reaction Conditions
    标题:Alkylstannanes
    作者:Crisp,G. T.
    参考文献:Science Of Synthesis 日期:2003 卷标:5 页码:463-478]

    1461-22-9 = 81353-38-0
    反应条件:1.1 Reagents: Butyllithium Solvents: Tetrahydrofuran,Hexane; -78 °C; -78 °C -> Rt; 1 H,Rt1.2 4 H,Rt -> 50 °C2.1 Solvents: Tetrahydrofuran; Overnight,Rt
    标题:Palladium-Catalyzed Diastereoselective Synthesis Of (Z)-Conjugated Enynyl Homoallylic Alcohols
    作者:Horino,Yoshikazu; Et Al
    参考文献:Advanced Synthesis & Catalysis 日期:2021 卷标:363(14) 页码:3592-3599]

    1461-22-9 + 1066-54-2 = 81353-38-0
    反应条件:1.1 Reagents: Butyllithium Solvents: Diethyl Ether,Hexane; 45 Min,-40 °C; 1.5 H,-40 °C1.2 -40 °C -> Rt; 24 H,Rt
    标题:Selective Green Coupling Of Alkynyltins And Allylic Halides To Trienynes Via A Tandem Double Stille Reaction
    作者:Meana,Isabel; Et Al
    参考文献:Advanced Synthesis & Catalysis 日期:2010 卷标:352(17) 页码:2887-2891]

    1066-54-2 + 1066-87-1 = 81353-38-0 [标题:Reaction Conditions
    标题:Efficient Synthesis Of 3H,5H-Pyrrolo[3,2-D]Pyrimidin-4-One
    作者:Brakta,Mohamed; Et Al
    参考文献:Journal Of The Chemical Society 日期:1992 卷标:(15) 页码:1883-4]

    1066-54-2 + 1067-52-3 = 81353-38-0
    反应条件:1.1 14 H,100 °C
    标题:Sequential Norrish Type Ii Photoelimination And Intramolecular Aldol Cyclization Of α-Diketones: Synthesis Of Polyhydroxylated Cyclopentitols By Ring Contraction Of Hexopyranose Carbohydrate Derivatives
    作者:Alvarez-Dorta,Dimitri; Et Al
    参考文献:Chemistry - A European Journal 日期:2013 卷标:19(31) 页码:10312-10333]

    1066-54-2 + 1067-52-3 = 81353-38-0
    反应条件:1.1 Catalysts: Zinc Bromide Solvents: Acetonitrile; 3 H,Rt1.2 Reagents: Water
    标题:Direct Synthesis Of Alkynylstannanes: Znbr2 Catalyst For The Reaction Of Tributyltin Methoxide And Terminal Alkynes
    作者:Kiyokawa,Kensuke; Et Al
    参考文献:Angewandte Chemie 日期:2011 卷标:50(44) 页码:10393-10396]

    1066-54-2 + 1067-52-3 = 81353-38-0
    反应条件:1.1 4 H,120 °C
    标题:Gold(I)-Catalyzed Carbothiolation Via Rearrangement Of S-Propargyl Group: An Access To 3-Allenyl Or 3-Indenyl Benzo[b]Thiophenes
    作者:Van Wesemael,Camille; Et Al
    参考文献:Advanced Synthesis & Catalysis 日期:2022 卷标:364(23) 页码:4141-4145]

    101069-08-3 + 1066-54-2 = 81353-38-0
    反应条件:1.1 Solvents: Tetrahydrofuran; Overnight,Rt
    标题:Palladium-Catalyzed Diastereoselective Synthesis Of (Z)-Conjugated Enynyl Homoallylic Alcohols
    作者:Horino,Yoshikazu; Et Al
    参考文献:Advanced Synthesis & Catalysis 日期:2021 卷标:363(14) 页码:3592-3599]

    997-50-2 + 6180-99-0 = 81353-38-0
    反应条件:1.1 Catalysts: Ruthenium(1+),[(1′,2′,3′,4′,5′,6′-η)-2,2′′,4,4′′,6,6′′-Hexamethyl[1,1′:3′,1′′-T... Solvents: Dichloromethane-D2; 2 H,30 °C2.1 Catalysts: Ruthenium(1+),[(1′,2′,3′,4′,5′,6′-η)-2,2′′,4,4′′,6,6′′-Hexamethyl[1,1′:3′,1′′-T... Solvents: Dichloromethane; 24 H,30 °C2.2 Reagents: Triethylamine Solvents: Pentane
    标题:Catalytic Dehydrogenative Stannylation Of C(Sp)-H Bonds Involving Cooperative Sn-H Bond Activation Of Hydrostannanes
    作者:Forster,Francis; Et Al
    参考文献:Journal Of The American Chemical Society 日期:2018 卷标:140(4) 页码:1259-1262
三丁基氯化锡置于正丁基锂体系中,用 四氢呋喃,正己烷 作为反应溶剂,化学反应 5.0H,反应生成 三丁基(三甲基甲硅烷基乙炔基)锡
参考文献:(Z)-共轭烯基高烯丙醇的钯催化非对映选择性合成
标题:(Z)-共轭烯基高烯丙醇的钯催化非对映选择性合成
摘要:描述了通过钯催化的三组分反应非对映选择性合成带有共轭 (Z)-烯炔的抗高烯丙醇.该反应具有底物范围广,官能团相容性好,(Z)-烯烃立体控制水平高的特点.在该反应中,Pd(0) 在串联序列的两个基本步骤中充当催化剂:1) 从双功能连接试剂反应生成硼化 π-烯丙基钯物种,诱导醛的 Umpolung 烯丙基化,以及 2) C(Sp 2)−c(Sp) 交叉耦合.所得产物的进一步转化突出了它们的合成效用.
DOI:10.1002/adsc.202100206

海关参考信息

专利信息


专利号:US-2005222048-A1
优先权日:2004-03-31
标 题 :Novel synthetic C-glycolipids, their synthesis and use to treat infections, cancer and autoimmune diseases
发明人：TSUJI MORIYA; FRANCK RICHARD; CHEN GUANGWU
权利人:UNIV NEW YORK
摘要:The invention is directed to novel compounds of formulae (I), (II) and (III): n nwherein X is O or NH; n R 3 is OH or a monosaccharide and R 4 is hydrogen, or R 3 is hydrogen and R 4 is OH or a monosaccharide; R 5 is hydrogen or a monosaccharide; and pharmaceutically acceptable salts or esters thereof. The invention is also directed to the use of the compounds both directly and as immune adjuvants for treating cancer, infectious diseases and autoimmune diseases. The invention is also directed to syntheses of the intermediates which can be used to make these novel compounds.

专利号:JP-6038111-B2
优先权日:2014-12-27
标 题:2,6-Dichloro-8-iodo-7-deazapurine for the synthesis of polysubstituted 7-deazapurine derivatives

专利号:US-6136823-A
优先权日:1996-11-28
标题 :Pyridonecarboxylic acid derivatives or salts thereof and drugs containing the same as the active ingredient
发明人：SAKAE NOBUYA; YAZAKI AKIRA; KURAMOTO YASUHIRO; YOSHIDA JIRO; NIINO YOSHIKO; OHSHITA YOSHIHIRO; HIRAO YUZO; HAYASHI NORIHIRO; AMANO HIROTAKA
权利人:WAKUNAGA PHARMA CO LTD
摘要:PCT No. PCT/JP97/04326 Sec. 371 Date May 28, 1999 Sec. 102(e) Date May 28, 1999 PCT Filed Nov. 27, 1997 PCT Pub. No. WO98/23592 PCT Pub. Date Jun. 4, 1998The invention relates to pyridonecarboxylic acid derivatives represented by the general formula (1): wherein R1 is -OH, a carboxy-protecting group or (alkyl)amino group, R2 is H, or -NO2, (protected) amino, (protected) hydroxyl, lower alkyl or lower alkoxyl group, R3 is a halogen atom, H, or -NO2, lower alkyl, lower alkoxyl or amino group, R4 is an azido, (substituted) hydrazino, (substituted) amino, lower alkoxyl or hydroxyl group, R5, R6 and R7 are independently H, -NO2, halogen atom or lower alkyl group, R8 is a -NO2, (substituted) amino, -OH or lower alkoxyl group, A is N or C-R12, in which R12 is H, halogen atom, or (substituted) lower alkyl, lower alkenyl, lower alkynyl, lower alkoxyl, lower alkylthio or nitro group, and B is N or C-R13, in which R13 is H or halogen atom, or salts thereof, and medicine comprising such a compound as an active ingredient. The derivatives or the salts thereof exhibit excellent antibacterial action and peroral absorbability, scarcely cause side effects, and are easy of synthesis.

专利号:CN-1964626-A
优先权日:2004-03-31
标题:Novel synthetic C-glycolipids, their synthesis and their use in the treatment of infectious diseases, cancer and autoimmune diseases

其他信息查阅

安徽济达化工科技有限公司
⚠️ 未注册 · 未认证企业
⚠️ 该商家尚未完成注册及企业认证，请用户仔细辨别，谨慎交易。
数据来源于公开网络搜索，平台未作核实，请自行辨别。
🏢敬请 企业认领
🏬开设公司展台
📢获取免费会员权益
🎖️点亮专属注册企业标签
📇展现公司完整信息 样本查看立即注册认领 →
网址: http://www.jidapharm.com
电话: 0556-5881618 18956990316👤
📞安徽济达化工科技有限公司 ⚠️参考联系方式

销售电话:0556-5881618 18956990316
邮箱：sales@jidapharm.com
🆔 联系时候可告知是从"百琢研"平台获取的信息.
⚠️ 声明: 该企业未认证、未认领，请自行辨别信息的真实性和可靠性。咨询或交易时请注意风险评估与信息核实，百琢研不参与任何交易。企业认领注册入口→

安徽省六安经济开发区纬一路中科智能创业园2号楼2层西侧
⚠️ 未注册 · 未认证企业
注册入口 备注: 📌 数据来源说明：本展台内容基于各搜索引擎等公开数据整理，仅作展示用途。请用户自行辨别 ✉️ 若企业需抹除展台内容或有异议， 请通过页面底部联系方式告知我们，我们会尽快处理。
第 1 / 1 页
现货

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

实用工具

⚠️全国化工行业净网倡议书
📋制造商识别码
📖 海关编码查询
📝MSDS生成器

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

主要参考文献

参考标题:Synthesis Of 1,2,3-Triazole Linked Galactopyranosides And Evaluation Of Cholera Toxin Inhibition
作者:David J. Leaver,Raymond M. Dawson,Jonathan M. White,Anastasios Polyzos,Andrew B. Hughes
摘要:We Report The Synthesis Of A Series Of Bivalent 1,2,3-Triazole Linked Galactopyranosides As Potential Inhibitors Of Cholera Toxin (Ct). The Inhibitory Activity Of The Bivalent Series Was Examined (Elisa) And The Series Showed Low Inhibitory Activity (Millimolar Ic50S). Conversely, The Monomeric Galactotriazole Analogues Were Strong Inhibitors Of Cholera Toxin (Ic50 = 71-75 μm).

合成参考文献


摘要:Griesbeck, A. G.; Soldevilla, A., Science of Synthesis, (2008) 43, 349.
摘要:Collier, S. J.; Singh, S. K., Science of Synthesis, (2010) 45, 80.
摘要:von Angerer, S., Science of Synthesis Knowledge Updates, (2011) 1, 371.
摘要:Patil, N. T.; Tathe, A. G.; Bhoyare, V. W., Science of Synthesis, (2019) , 127.
摘要:Sawamura, M.; Ohmiya, H., Science of Synthesis: Advances in Organoboron Chemistry towards Organic Synthesis, (2019) 1, 105.
📝 需求与反馈
尽可能描述清楚需求与问题信息
×

通知