CAS: 110-86-1; Pyridine

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Pyridin-1-Ium置于aminoalcohol 7体系中,化学反应生成吡啶
参考文献:质子化位点和构象对 β-氨基醇中气相碱性的影响.β-羟基铵离子内部氢键的性质
标题:质子化位点和构象对 β-氨基醇中气相碱性的影响.β-羟基铵离子内部氢键的性质
摘要:注:Univ Lausanne,Inst Chim Organ,Ch-1005 Lausanne,瑞士.捷克斯洛伐克 Acad Sci,Inst 器官化学和生物化学,Cs-16610 布拉格 6,捷克斯洛伐克.参考 Lgsa-Article-1983-005Doi:10.1021/ja00349A006查看 Web Of Science 记录中的记录,创建于 2005-11-09,修改于 2017-05-12
Doi:10.1021/ja00349A006

专利信息

专利号:US-2025313590-A1
优先权日:2024-03-16
标题:Phosphoramidite morpholino monomers towards synthesis/convergent synthesis of PMO, TMO, their chimera oligos in 5 prime to 3 prime direction
发明人：SINHA SURAJIT; GHOSH ATANU; BANERJEE ARPAN
权利人:INDIAN ASS FOR THE CULTIVATION OF SCIENCE
摘要:The present invention relates to 5′-morpholino amidite monomers as 5′-CE/5′- t Bu phosphoramidite morpholino monomers (2) and process chemistry for the efficient synthesis of N-Trityl or monomethoxytrityl (MMTr)-protected 5′-morpholino amidite monomers and their use in the synthesis of phosphorodiamidate morpholino oligonucleotides (PMO), thiophosphoramidate morpholino oligonucleotides (TMO) and their chimeras which can be used for antisense technology or in general oligonucleotides related research.

专利号:US-12012427-B2
优先权日:2019-10-31
标 题 :Synthesis of Fmoc-protected morpholino monomers and their use in the synthesis of morpholino oligomer
发明人：SINHA SURAJIT; KUNDU JAYANTA; GHOSH UJJWAL
权利人:INDIAN ASS FOR THE CULTIVATION OF SCIENCE
摘要:Present invention relates to stable Fmoc protected Morpholino monomers and corresponding oligonucleotides (PMO) and efficient synthesis of the same involving chlorophosphoramidate and H-Phosphonate chemistry. Successful syntheses of the oligonucleotide with higher yield and lesser time have been accomplished employing solid phase synthesis and easy deprotection of Fmoc group with Piperidine.

专利号:WO-2021014395-A1
优先权日:2019-07-24
标题:Process for the synthesis of deuterated capsaicin, capsaicinoids and synthetic capsaicin analogs
发明人：ORUGANTI SRINIVAS; AMRUTAPU SRAVANTH KUMAR; SAMPATH MAGESH; SEN SAIKAT
权利人:DR REDDY’S INST OF LIFE SCIENCES
摘要:The present application provides novel processes for the synthesis of deuterated intermediates of capsaicinoids, particularly II, III, IV and V of capsaicinoids, relating to pharmaceutical applications. The invention also provides novel intermediates of compounds of formula IX, XIV, XV, XVI, XVII, XVIII, XX and XXI utilized in the process of making deuterated capsaicin II, III, IV and V.

专利号:WO-2021260722-A1
优先权日:2020-06-21
标 题:Design, synthesis of novel oxyindole inhibitors of denv rna dependent rna polymerase
发明人：GUNDLA RAMBABU; ASTHANA SHAILENDRA; BHATTACHARYYA SANKAR; MADDIPATI VENKATANARAYANA CHOWDARY; MITTAL LOVIKA; KAUR JASKARAN; RAWAT YOGITA
权利人:TRANSLATIONAL HEALTH SCIENCE AND TECH INSTITUTE; GANDHI INSTITUTE OF TECH AND MANAGEMENT
摘要:The present invention is drawn to novel compounds of formula I, II and III, including any conformational isomeric form, salts and solvates for inhibition of DENV RNA dependent and RNA polymerase. The present invention also discloses a process of synthesis of the compounds, compositions comprising the said compounds and use of the compounds and treatment comprising the compounds of the present invention.

专利号:US-7160517-B2
优先权日:2000-08-18
标题 :Apparatus and methods for the automated synthesis of oligosaccharides
发明人：SEEBERGER PETER H; PLANTE OBADIAH J
权利人:MASSACHUSETTS INST OF TECHNOLG
摘要:One aspect of the present invention relates to an apparatus for the efficient synthesis of oligosaccharides on a solid support, e.g., formed by subunit addition to terminal subunits immobilized on solid-phase particles. In certain embodiments, the apparatus of the present invention is used in combinatorial methods, e.g., as described herein, of synthesizing oligosaccharides.

专利号:US-6794534-B2
优先权日:2000-06-23
标题:Synthesis of functionalized and unfunctionalized olefins via cross and ring-closing metathesis
发明人：GRUBBS ROBERT H; CHATTERJEE ARNAB K; MORGAN JOHN P; SCHOLL MATTHIAS; CHOI TAE-LIM
权利人:CALIFORNIA INST OF TECHN
摘要:The invention is directed to the cross-metathesis and ring-closing metathesis reactions between geminal disubstituted olefins and terminal olefins, wherein the reaction employs a Ruthenium or Osmium metal carbene complex. Specifically, the invention relates to the synthesis of α-functionalized or unfunctionalized olefins via intermolecular cross-metathesis and intramolecular ring-closing metathesis using a ruthenium alkylidene complex. The catalysts preferably used in the invention are of the general formula n wherein: n M is ruthenium or osmium; n X and X 1 are each independently an anionic ligand; n L is a neutral electron donor ligand; and, n R, R 1 R 6 , R 7 , R 8 , and R 9 are each independently hydrogen or a substituent selected from the group consisting of C 1 -C 20 alkyl, C 2 -C 20 alkenyl, C 2 -C 20 alkynyl, aryl, C 1 -C 20 carboxylate, C 1 -C 20 alkoxy, C 2 -C 20 alkenyloxy, C 2 -C 20 alkynyloxy, aryloxy, C 2 -C 20 alkoxycarbonyl, C 1 -C 20 alkylthio, C 1 -C 20 alkylsulfonyl and C 1 -C 20 alkylsulfinyl.