CAS: 308103-40-4; (2-Acetylphenyl)Boronic Acid

上下游产品

CAS号2142-68-9 邻氯苯乙酮 | CAS号50777-64-5 2-(2-溴苯基)-2-甲基-... | CAS号243140-14-9 2-(2-甲基-1,3-二氧戊... | CAS号232611-22-2 ETHYL 10-METHYL... | CAS号17024-15-6 9-Phenanthrenec... | CAS号24017-95-6 2,2'-Diacetylbi... | CAS号2142-66-7 1-([1,1'-联苯]-2-基)乙酮 | CAS号858035-57-1 4-(2-acetylphen... | CAS号4444-43-3 dibenzo[1,2-d:1... | CAS号55042-80-3 methyl 10-methy... | CAS号61608-94-4 1-(2-benzylphen... | CAS号5418-21-3 1-methyl-2,3-di...

邻氯苯乙酮置于四羟基二硼,氯(2-二环己基膦基-2',4',6'-三异丙基-1,1'-联苯基)[2-(2'-氨基-1,1'-联苯)]钯(II),Potassium Acetate,2-二环己基磷-2,4,6-三异丙基联苯体系中,用 甲醇 用作溶剂,化学反应 2.0H,反应生成2-乙酰苯基硼酸
参考文献:使用双硼酸的钯催化芳基硼化反应的范围
标题:使用双硼酸的钯催化芳基硼化反应的范围
摘要:Suzuki-Miyaura 反应已成为合成有机化学家更有用的工具之一.直到最近,还没有直接的方法来制造偶联反应中最重要的成分,即硼酸.目前制造硼酸的方法通常使用苛刻或浪费的试剂来制备硼酸衍生物,并且需要额外的步骤来提供所需的硼酸.先前报道的钯催化的直接硼酸合成的范围被揭开,其中包括广泛的合成有用的芳基亲电试剂.它利用新推出的第二代 Buchwald Xphos 预制钯催化剂和双硼酸.为了便于隔离并保留通常敏感的 Cb 键,
Doi:10.1021/ja303181M

专利信息

专利号:US-8207337-B2
优先权日:2007-01-29
标 题:Reagent for organic synthesis reaction containing organic triol borate salt
发明人：MIYAURA NORIO; YAMAMOTO YASUNORI
权利人:MIYAURA NORIO; YAMAMOTO YASUNORI; WAKO PURE CHEM IND LTD
摘要:[Problem] n To provide an organoboron compound-containing reagent for organic synthesis reactions which undergoes no trimerization with dehydration, does not necessitate activation with a base, and is stable and highly active. n [Means for Solving Problems] n The reagent for organic synthesis reactions contains an organic triol borate salt represented by any of the general formulae (I) to (III) and general formula (XVI): (wherein R 1 represents alkyl, alkenyl, etc.; R 2 represents optionally substituted alkyl, alkenyl, alkynyl, etc. or represents hydrogen; m + represents an alkaline metal ion, phosphonium ion, or given ammonium ion; M 2+ represents an alkaline earth metal; X represents halogen or alkoxide; Y represents an alkali metal ion, etc.; A represents optionally substituted methylene; and n represents an integer).

专利号:US-2008280933-A1
优先权日:2006-07-25
标 题:Benzimidazolyl compounds
发明人：EFREMOV IVAN; ROGERS BRUCE N; DUPLANTIER ALLEN J; ZHANG LEI; ZHANG QIAN; MAKLAD NOHA S; EVRARD EDELWEISS; BRODNEY MICHAEL A
权利人:EFREMOV IVAN; ROGERS BRUCE N; DUPLANTIER ALLEN J; ZHANG LEI; ZHANG QIAN; MAKLAD NOHA S; EVRARD EDELWEISS; BRODNEY MICHAEL A
摘要:Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I n n n n n n n n n n as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

专利号:CN-116836235-A
优先权日:2022-03-25
标 题 :Affinity fragment-directed cleavable fragments, their design, synthesis and application in the preparation of site-directed drug conjugates

专利号:EP-4501945-A1
优先权日:2022-03-25
标 题:Cleavable fragment directed by affinity fragment, design and synthesis thereof, and use thereof in preparation of site-directed drug conjugate

专利号:CN-117126397-A
优先权日:2023-08-18
标 题:Synthesis methods and applications of protein-bound precision polyethylene glycol