CAS: 581-42-0; 2,6-Dimethylnaphthalene

该化合物是氯化萘家族的有机化合物,其特点是两个有引信的芳香环;其分子式C12H10具有2和6个位置,其特性为与氯化萘结构相连的两个甲基组;该化合物在室内温度下无色可粉黄,具有明显的芳香味;水中相对不溶,但在乙醇和乙醚等有机溶剂中可溶. 2,6-二甲基甲苯主要用于各种化学中间体的合成和工业应用中的溶剂,其熔点高于氯化萘的溶点,表明由于存在甲基组,分子相互作用的程度更大.此外,该化合物具有中度毒性,应谨慎处理,因为它在接触皮肤或眼睛时会引起刺激.

结构式图片

相似化合物

582-16-1 571-58-4 575-41-7

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

acetylacetaldehyde dimethyl acetal 4-tolylmagnesium chloride 1,6-dimethylnaphthalene 2-iodo-6-methylnaphthalene 2-(2,6-dimethyl-[1]naphthoyl)-benzoic acid 2-(3,7-dimethyl-1-naphthoyl)benzoic acid 2,6-dimethyltetralin decahydro-2,6-dimethylnaphthalene

合成工艺路线路线简述

    3-甲基-4-(对甲苯基)丁醛置于iron(Iii) Chloride体系中,用 1,1,2-三氯乙烷 作为反应溶剂,化学反应 2.0H,以79%的收率获得产物2,6-二甲基萘
    参考文献:Wo2007/64105
    标题:Wo2007/64105

    海关参考信息

    专利信息


    专利号:US-2010143980-A1
    优先权日:2007-02-22
    标题:Synthesis of novel xylosides and potential uses thereof
    发明人:BALAGURUNATHAN KUBERAN; MANIVANNAN ETHIRAJAN; XYLOPHONE V VICTOR; TRAN VY MY; NGUYEN KHIEM
    权利人:BALAGURUNATHAN KUBERAN; MANIVANNAN ETHIRAJAN; XYLOPHONE V VICTOR; TRAN VY MY; NGUYEN KHIEM
    摘要:The present invention includes a xyloside for use in inducing synthesis of a glycosaminoglycan in a cell, the xyloside having a chemical structure of one of Formula (1), Formula (2), Formula (3), Formula (4), Formula (5), Formula (6), Formula (7), Formula (8), Formula (9), or Formula (10) as shown herein. Also, the present invention includes a method of making a xyloside for use in inducing synthesis of a glycosaminoglycan in a cell, wherein the method is performed with “Clickâ€? chemistry. Additionally, the present invention includes a method of administering a xyloside so as to induce synthesis of a glycosaminoglycan in a cell.

    专利号:US-2003162992-A1
    优先权日:2001-12-14
    标 题 :Preparation of intermediates useful in the synthesis of antiviral nucleosides
    发明人:WATANABE KYOICHI A; DU JINFA
    摘要:The present invention is an efficient process for the manufacture of α-acyloxyacetaldehyde, a key intermediate in the synthesis of 1,3-oxathiolane and 1,3-dioxolane nucleosides.

    专利号:US-12312304-B2
    优先权日:2021-09-14
    标题:Method for continuous synthesis of acylnaphthalene with acylation liquid
    发明人:MAO XUEFENG; LI HENG; HU FATING; ZHONG JINLONG; LI JUNFANG; WANG TONG; ZHANG XIAORAN
    权利人:CCTEG CHINA COAL RES INSTITUTE
    摘要:A method for continuous synthesis of acylnaphthalene includes: mixing a raw solution containing 2-methylnaphthalene with an acylation liquid to obtain an acylation reaction liquid with a molar ratio of the 2-methylnaphthalene: the acylation agent: the Lewis catalyst of 1:1.3:1.5; adding the acylation reaction liquid into a microchannel reactor and a plurality of kettle reactors connected in series to perform acylation reaction, performing hydrolysis reaction on the acylation reaction liquid immediately after the acylation reaction liquid flows out of the plurality of kettle reactors to obtain a mixed solution, and subjecting the mixed solution to separation, rectification and crystallization, to obtain 2-methyl-6-propionylnaphthalene.

    专利号:US-11306041-B2
    优先权日:2017-03-30
    标 题:Catalytic synthesis of super linear alkenyl arenes using rhodium catalysts
    发明人:SCHINSKI WILLIAM; GOLDMAN ALAN; GUNNOE THOMAS B; WEBSTER-GARDINER MICHAEL S; SCHWARTZ NICHOLE
    权利人:UNIV VIRGINIA PATENT FOUNDATION
    摘要:Catalytic methods for synthesis of super linear alkenyl arenes and alkyl arenes are provided. The methods are capable of synthesizing super linear alkyl and alkenyl arenes from simple arene and olefin starting materials and with high selectivity for linear coupling. Methods are also provided for making a 2,6-dimethylnapthalene (DMN) or 2,6-methylethylnapthalene (MEN).

    专利号:US-6495710-B2
    优先权日:2000-01-14
    标题:Synthesis and use of dimethyl 1,5-naphthalenedicarboxlyates and intermediates therefrom
    发明人:MACEK JOHN A; ROSEN BRUCE I; HOLZHAUER JUERGEN K; BRAMLET JOHN S; LILLWITZ LARRY D; SCHNEIDER DAVID J; LANG LAWRENCE L; PASCHKE EDWARD E; WEIS JOHN M; VISWANATH YENAMANDRA; SAKELLARIDES STEFANOS L
    权利人:BP CORP NORTH AMERICA INC
    摘要:The synthesis of dimethyl-1,5-naphthalenedicarboxylate and polymers and articles formed therefrom is disclosed, as well as applications for dimethyl-1,5-naphthalenedicarboxylate, its corresponding acid 1,5-NDA, and various synthesis intermediates.

    专利号:US-6197920-B1
    优先权日:1999-07-21
    标 题:Formulation for the production of 1, 3-bis (4-aminophenoxy) naphthalene and its polymer
    发明人:CHENG KUN LIN; CHEN WEN-TUNG
    权利人:CHINA TEXTILE INST
    摘要:The present invention relates to the synthesis of new type of diamine monomer, 1,3-bis(4-amonophenoxy)naphthalene, and with such a compound to produce a series of aromatic polymers, including polyamide, polyimide, copoly(amide-imide)s, etc., such polymers having excellent resistance to heat and mechanical properties.
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    合成参考文献


    摘要:Toyota, S.; Iwanaga, T., Science of Synthesis, (2010) 45, 764.
    摘要:Barsegyan, Y. A.; Vil’, V. A.; Tomkinson, N. C. O.; Terent’ev, A. O., Science of Synthesis Knowledge Updates, (2022) 1, 239.
    摘要:Hitomi, Y.; Arakawa, K., Science of Synthesis: Catalytic Transformations via CH Activation, (2015) 2, 297.
    摘要:Dai, X.; Shi, F., Science of Synthesis: Catalytic Reduction in Organic Synthesis, (2017) 1, 143.
    参考文献:10.1007/s002449900508
    摘要:Hufnagle Jr. LC, Camarata SE, Ernest D, Krone CA, Chan S-, Krahn MM. Development and Application of a High-Performance Liquid Chromatography Screening Method for Aromatic Compounds in Invertebrate Tissues. Archives of Environmental Contamination and Toxicology. 1999 Aug;37(2):220–6. doi: 10.1007/s002449900508.
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