CAS: 7657-09-2; 1,4-Dibromo-2-(Trifluoromethyl)Benzene

上下游产品

α,α,α-trifluorotoluene N-acetyl-3-trifluoromethylbenzenamine N-(4-bromo-3-trifluoromethylphenyl)acetamide 4-bromo-3-(trifluoromethyl)aniline 2,5-dibromobenzoic acid 1-(2-bromo-4-trifluoromethyl-phenyl)-ethanol 1,4-diiodo-2-(trifluoromethyl)benzene 4-dibromo-2-(trifluoromethyl)benzaldehyde

5-乙酰胺基-2-溴三氟甲苯置于盐酸,Sodium Nitrite体系中,用 水 作为反应溶剂,化学反应 1.0H,反应生成 2,5-二溴三氟甲苯
参考文献: Process For The Preparation Of Substituted Benzotrihalide[fr] Procédé De Préparation De Benzotrihalogénure Substitué
标题: Process For The Preparation Of Substituted Benzotrihalide[fr] Procédé De Préparation De Benzotrihalogénure Substitué
摘要:本发明提供一种制备化合物i的方法;其中x选自氟,氯,溴和碘组成的群;y选自x和-Nr1R2;r1和r1,彼此独立,选自氢,C1-4烷基和-Cor组成的群;r为c1-4烷基.

专利信息

专利号:US-7615300-B2
优先权日:2005-08-30
标 题 :Development of novel proton-conductive polymers for proton exchange membrane fuel cell (PEMFC) technology
发明人：BAE CHULSUNG
权利人:REGENTS UNIVERSITY AND COMMUNI
摘要:New thermally and chemically stable sulfonic acid-containing polymers are synthesized via post-sulfonation of aromatic polymers. These new polymers provide unique benefits to proton exchange membrane fuel cell technology (“PEMFCâ€?). As a sulfonic acid moiety can be easily installed into an aromatic ring via electrophilic sulfonation, even in the presence of an electron-withdrawing substituent such as —F, rigid polymers consisting of aromatic rings at either the side chain or main chain can be prepared with a wide range of substituents and flexibility in properties. Novel synthetic procedures are provided for synthesis of the polymers.

专利号:US-9428500-B2
优先权日:2012-05-11
标 题 :Alpha-carbolines for the treatment of cancer
发明人：GAMBACORTI-PASSERINI CARLO; MOLOGNI LUCA; SCAPOZZA LEONARDO; BISSON WILLIAM; AHMED SHAHEEN; GOEKJIAN PETER; TARDY SÉBASTIEN; ORSATO ALEXANDRE; GUEYRARD DAVID; BENOIT JOSEPH
权利人:UNIVERSITA' DEGLI STUDI DI MILANO—BICOCCA; UNIV GENEVE; UNIVERSITÉ CLAUDE BERNARD—LYON 1; UNIV DEGLI STUDI DI MILANO—BICOCCA; UNIV GENEVE; UNIV CLAUDE BERNARD—LYON
摘要:The present invention relates to inhibitors of the oncogenic protein kinase ALK of formula (I) as herein described and pharmaceutical compositions thereof, as well as to key intermediates towards their synthesis. The compounds of formula (I) are useful in the preparation of a medicament, in particular for the treatment of cancer.