CAS: 87942-08-3; Magnesium,Propylbenzene,Bromide

该化合物是一种有机磁性化合物,通常用作有机合成中的灰色试剂,其主要优点包括对电极具有高度的回动性,使其在构建复杂分子的过程中对形成碳-碳联系具有价值.丙基苯组会提高非极溶剂的溶性,便利各种反应条件下的处理.该试剂特别有助于制药,农用化学品和特殊化学品的准备,需要选择性的功能化.在受控条件下和可预测的回动特征下,其稳定性确保合成应用的一贯性能.建议在惰性大气中适当地储存,以保持其功效.

英文名称Magnesium,Propylbenzene,Bromide
中文名称4-正丁基苯基溴化镁
IUPAC名称magnesium;propylbenzene;bromide
其它别名Benzene,propyl-, magnesium complex; (4-Propylphenyl)magnesium bromide; p-Propylphenylmagnesium bromide
CAS编号87942-08-3
MFCD编号:MFCD01311466
EINECS号:804-309-9
分子式:C9H11BrMg
分子量:223.4
产品CID: 1888464
产品分类有机原料 → 有机金属类化合物 → 有机镁

相似结构搜索
InChIKey: URDLBLBYYUFLSI-UHFFFAOYSA-M
1S/C9H11.BrH.Mg/c1-2-6-9-7-4-3-5-8-9;;/h4-5,7-8H,2,6H2,1H3;1H;/q;;+1/p-1…
计算化学: 氢键受体数2.0氢键供体数0.0可旋转键数2.0

MSDS等安全信息

GHS象形图
GHS符号GHS05;
注释: Corrosion
危险类别皮肤腐蚀类别1B
警示词Danger(危险)
危险描述H314 |造成严重皮肤灼伤和眼损伤.
防范说明P210-P260-P280-P305+P351+P338-P370+P378-P403+P235
UN编号UN 2924 3/PG 2
危险品标志F,C
安全声明16-29-33-45-36/37/39-26
危险类别码11-14-19-34-40-37
WGK Germany1.0

欧盟法规

C&L通报

上下游产品

合成工艺路线路线简述

588-93-2 = 87942-08-3
反应条件:1.1 Reagents: Magnesium Catalysts: 1,2-Dibromoethane Solvents: Diethyl Ether; 2 Min,Heated; 3 H,0 °C; 30 Min,0 °C
标题:Synthesis Of Bicyclo[1.1.1]Pentane Bioisosteres Of Internal Alkynes And Para-Disubstituted Benzenes From [1.1.1]Propellane
作者:Makarov,Ilya S.; Et Al
参考文献:Angewandte Chemie 日期:2017 卷标:56(41) 页码:12774-12777]

588-93-2 = 87942-08-3
反应条件:1.1 Reagents: Magnesium,Iodine Solvents: Tetrahydrofuran; 2 H,Reflux1.2 Reagents: Water
标题:Transmembrane Chloride Transport By Diphosphine-Pd(Ii) Complexes: Effect Of The Ligand Geometry
作者:Vidal,Alessio; Et Al
参考文献:European Journal Of Organic Chemistry 日期:2022 卷标:2022(44)

海关参考信息

2902600000-乙苯
2901100000-饱和无环烃
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

专利号:US-9839664-B2
优先权日:2014-07-25
标题 :GLP-1 receptor modulators
发明人：BOEHM MARCUS F; MARTINBOROUGH ESTHER; MOORJANI MANISHA; TAMIYA JUNKO; HUANG LIMING; YEAGER ADAM R; BRAHMACHARY ENUGURTHI; FOWLER THOMAS; NOVAK ANDREW; MEGHANI PREMJI; KNAGGS MICHAEL
权利人:CELGENE INT II SÃ€RL
摘要:Compounds are provided that modulate the glucagon-like peptide 1 (GLP-1) receptor, as well as methods of their synthesis, and methods of their therapeutic and/or prophylactic use. Such compounds can act as modulators or potentiators of GLP-1 receptor on their own, or with incretin peptides such as GLP-1(7-36), GLP-1(9-36), and oxyntomodulin, or with peptide-based therapies, such as exenatide and liraglutide, and have the following general structure (where â€œ â€? represents either or both the R and S form of the compound): n nwhere A, B, C, R 1 , R 2 , R 3 , R 4 , R 5 , n, p and q are as defined herein.

专利号:US-9795613-B2
优先权日:2014-12-10
标题 :GLP-1 receptor modulators
发明人：BOEHM MARCUS F; MARTINBOROUGH ESTHER; MOORJANI MANISHA; TAMIYA JUNKO; HUANG LIMING; YEAGER ADAM R; BRAHMACHARY ENUGURTHI; FOWLER THOMAS; NOVAK ANDREW; MEGHANI PREMJI; KNAGGS MICHAEL; GLYNN DANIEL; MILLS MARK
权利人:CELGENE INT II SÃ€RL
摘要:Compounds are provided that modulate the glucagon-like peptide 1 (GLP-1) receptor, as well as methods of their synthesis, and methods of their therapeutic and/or prophylactic use. Such compounds can act as modulators or potentiators of GLP-1 receptor on their own, or with incretin peptides such as GLP-1(7-36) and GLP-1(9-36), or with peptide-based therapies, such as exenatide and liraglutide, and have the following general structure (where â€œ â€? represents either or both the R and S form of the compound): n nwhere A, B, C, Y 1 , Y 2 , Z, R 1 , R 2 , R 3 , R 4 , R 5 , W 1 , n, p and q are as defined herein.