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2-chloro-5-fluoroaniline m,p-dichloroaniline 2,3-dichlorofluorobenzene sulfuric acid 3,4-dichlorophenol 3,4-dichloroanisole 1,2-dichloro-4-fluoro-5-nitrobenzene 1,2,4-Tribromo-5,6-dichloro-3-fluoro-benzene (3,4-二氯苯基)三氟硼酸钾置于lithium Hydroxide Monohydrate,Silver Trifluoromethanesulfonate,Selectfluor体系中,用 乙酸乙酯 用作溶剂,以75%的收率获得1,2-二氯-4-氟苯
参考文献:Silver-Mediated Fluorination Of Potassium Aryltrifluoroborates With Selectfluor®
标题:Silver-Mediated Fluorination Of Potassium Aryltrifluoroborates With Selectfluor®
摘要:A Simple And Practical Procedure For The Silver-Mediated Fluorination Of Aryl-And Heteroaryltrifluoroborates With Electrophilic Fluorine From Selectfluor (R) And Lioh Center Dot H2O Is Presented. The Reaction Procedure Is Simple And Easy To Set Up,The Process Produces Fluorinated Arenes And Heteroarenes In Good To Excellent Yields And A Wide Range Of Electronically And Structurally Diverse Substrates Are Tolerated. (C) 2014 Elsevier Ltd. All Rights Reserved.
Doi:10.1016/j.Tet.2014.10.055
专利信息
专利号:US-7393980-B2
优先权日:2001-05-17
标题:Use of a composition of an ionic nature as a substrate reagent, a composition constituting a fluorination reagent and a method using same
发明人:GARAYT MAXIME; LE BOULAIRE VIRGINIE; GREE DANIELLE; GREE RENE; SCHANEN VINCENT; SPINDLER JEAN-FRANCIS
权利人:RHODIA CHIMIE SA
摘要:The invention relates to a novel method for producing nucleophilic substitutions, particularly of type SNAr and SN2. More specifically, the invention relates to the use as a fluorinating reaction medium of ionic liquid or fused salt comprising at least four carbon atoms. The invention can be used for the synthesis of fluoride derivatives.
专利号:CN-118666668-A
优先权日:2024-06-11
标题:Clinical study on the synthesis of 4,5-dichloro-2-fluorobenzoic acid, a synthetic building block for pain medication
专利号:CN-105130744-A
优先权日:2015-08-19
标题 :Synthesis of 1,3,5-trichloro-2,4,6-trifluorobenzene from a 2,4-difluoro-3,5-dichloronitrobenzene
专利号:RU-2144023-C1
优先权日:1994-03-08
标题 :Substituted benzamides, method of their synthesis, intermediate compounds, composition and method of control of plant sweating out sickness
专利号:CN-105130744-B
优先权日:2015-08-19
标题:A kind of 2,4 difluoro 3,5 dichloronitrobenzene synthesis 1,3,5 trichlorine, 2,4,6 trifluoro-benzene