Boron Trioxide置于乙醇体系中,化学反应生成硼酸三乙酯 参考文献:Copaux,Comptes Rendus Hebdomadaires Des Seances De L'Academie Des Sciences,1898,Vol. 127,P. 719 标题:Copaux,Comptes Rendus Hebdomadaires Des Seances De L'Academie Des Sciences,1898,Vol. 127,P. 719
专利号:US-5679864-A 优先权日:1995-11-03 标题:Process for the synthesis of curcumin-related compounds 发明人:KRACKOV MARK HARRY; BELLIS HAROLD EDWARD 权利人:GENE PRINT INC 摘要:The invention is directed to a process for the synthesis of curcumin and curcumin-related compounds by reacting the enol form of a 2,4-diketone with a monocarbocyclic aldehyde in the presence of an organic amine catalyst. The reactants are dissolved in a highly polar, aprotic organic solvent. The curcumin-related product is recovered in crystalline form by precipitation from the reaction mass and solvent recrystallization.
专利号:US-2014255328-A1 优先权日:2013-03-11 标 题:Hydrothermal Synthesis of Zinc Phlogopite 发明人:MCGUIRE MEAGHAN CLARK; BULL IVOR; JOHNSON GEOFFREY MARK 权利人:BASF SE 摘要:This invention relates to a synthetically derived zinc phlogopite platelets, of superior platelet diameter, effect pigments comprising such synthetically derived platelets and methods of forming said substrates. More specifically the disclosure describes an improved hydrothermal synthesis of zinc phlogopite suitable as a platelets for interference pigments, barrier and flame retardant applications.
专利号:US-12391691-B2 优先权日:2018-11-16 标题:Synthesis of key intermediate of KRAS G12C inhibitor compound 发明人:PARSONS ANDREW THOMAS; COCHRAN BRIAN MCNEIL; POWAZINIK IV WILLIAM; CAPORINI MARC ANTHONY 权利人:AMGEN INC 摘要:The present invention relates to an improved, efficient, scalable process to prepare intermediate compounds, such as compound 5M, having the structure n nuseful for the synthesis of compounds that target KRAS G12C mutations, such as
专利号:US-11702380-B2 优先权日:2021-03-10 标 题:Synthesis of omecamtiv mecarbil 发明人:CAILLE SEBASTIEN; MURRAY JAMES; QUASDORF KYLE; NGUYEN HANNAH; SILVA ELIPE MARIA VICTORIA; ERICSON ARI ELIZABETH 权利人:AMGEN INC 摘要:Provided herein are synthetic methods for the preparation of intermediates that are utilized in the synthesis of omecamtiv mecarbil dihydrochloride.
专利号:WO-2024018354-A1 优先权日:2022-07-18 标题 :A process for the synthesis of 4-alkoxy-3-hydroxypicolinic acids and intermediates thereof 发明人:MAL SANJIB; SARKAR PARANTAP; PATRA PRANAB KUMAR; KLAUSENER ALEXANDER GUENTHER MARIA 权利人:PI INDUSTRIES LTD 摘要:The present invention discloses a process for the synthesis of 4- alkoxy-3-hydroxypicolinic acids of formula (I) from 2-picolinic acid. The present invention further discloses a process for preparation of compounds of formula (iii) from compounds of formula (ii). The present invention also discloses novel intermediate compounds of formula (iii).
专利号:US-3891594-A 优先权日:1972-04-07 标题:Direct synthesis of composite materials 发明人:TAYLOR LYNN J 权利人:TAYLOR LYNN J 摘要:There is disclosed an in situ process for the preparation of a composite material consisting essentially of an organic polymer or copolymer having dispersed therein an inorganic oxide or mixture of oxides, said process comprising the simultaneous or sequential synthesis of the organic polymer from at least one non-polymeric organic precursor and of the inorganic oxide or oxide mixture derived from at least one inorganic-oxide precursor.