CAS: 61597-98-6; (S)-(1R,2S,5R)-2-Isopropyl-5-Methylcyclohexyl 2-Hydroxypropanoate

相似化合物

111969-64-3 2623-23-6 17162-29-7

上下游产品

2-Oxo-propionic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl propionate L-Lactic acid (-)-menthol(R)-[(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl] 2-(2-iodophenoxy)propanoate

2-Oxo-Propionic Acid (1R,2S,5R)-2-Isopropyl-5-Methyl-Cyclohexyl Ester置于rh Catalyst 1-Naphthylphenylsilane体系中,用 苯 作为反应溶剂,化学反应生成 L-乳酸薄荷酯
参考文献:Reduction Of Carbonyl Compounds Via Hydrosilylation. 3. Asymmetric Reduction Of Keto Esters Via Hydrosilylation Catalyzed By A Rhodium Complex With Chiral Phosphine Ligands
标题:Reduction Of Carbonyl Compounds Via Hydrosilylation. 3. Asymmetric Reduction Of Keto Esters Via Hydrosilylation Catalyzed By A Rhodium Complex With Chiral Phosphine Ligands
摘要:
DOI:10.1021/jo00430A001

专利信息

专利号:US-2024082118-A1
优先权日:2021-05-19
标 题:Topical compositions and methods of preparing the same
发明人：ABRAMOVICH SAGI; AVIDOR GAL; LANDA BENZION
权利人:LANDA LABS 2012 LTD
摘要:There is disclosed a composition comprising a water-insoluble thermoplastic compound capable of stimulating collagen synthesis (CSSC), the CSSC having a molecular weight of more than 0.6 kDa and being dispersed in a polar carrier as nano-elements having an average diameter of 200 nm or less and a viscosity of 107 mPa·s or less. The nano-elements of CSSC can be capable of stimulating the synthesis of skin proteins and/or enabling the delivery of active agents upon their application to a surface to be treated therewith. Methods for preparing the compositions and uses thereof are also provided.

专利号:US-8754259-B2
优先权日:2008-08-15
标 题 :Synthesis of cyclohexane derivatives useful as sensates in consumer products
发明人：YELM KENNETH EDWARD; BUNKE GREGORY MARK; HAUGHT JOHN CHRISTIAN
权利人:PROCTER & GAMBLE; PROCTER & GAMBLE
摘要:The present invention provides synthetic routes for preparing various isomers of cyclohexane-based coolants, such as menthyl esters and menthanecarboxamide derivatives, in particular those substituted at the amide nitrogen, for example with an aromatic ring or aryl moiety. Such structures have high cooling potency and long lasting sensory effect, which make them useful in a wide variety of consumer products. One synthetic route involves a copper catalyzed coupling of a primary menthanecarboxamide with an aryl halide, such reaction working best in the presence of potassium phosphate and water. Using this synthetic route, specific isomers can be prepared including the menthanecarboxamide isomer having the same configuration as l-menthol and new isomers such as a neoisomer having opposite stereochemistry at the carboxamide (C-1) position. The neoisomer unexpectedly has potent and long lasting cooling effect. Preparation schemes for neoisomers of other menthyl derivatives which are useful as coolants, including esters, ethers, carboxy esters and other N-substituted carboxamides are also provided.

专利号:US-2025144039-A1
优先权日:2022-07-13
标题:Compositions comprising surface modified globular nano-particles
发明人：ABRAMOVICH SAGI; AVIDOR GAL; LANDA BENZION
权利人:LANDA LABS 2012 LTD
摘要:There are disclosed compositions comprising core-shell nano-elements composed in their core of a water-insoluble thermoplastic compound having a molecular weight of more than 0.6 kDa and in their shell of at least one fatty amine, or a part thereof, the core-shell nano-elements having a viscosity of 107 mPa·s or less and being dispersed in a polar carrier as nano-elements having an average diameter of 200 nm or less. The water-insoluble thermoplastic compound can be capable of stimulating the synthesis of skin proteins and/or enabling the delivery of active agents upon application of the core-shell nano-elements to a surface to be treated therewith. Methods for preparing the composition and uses thereof are also provided.

专利号:WO-2024013694-A1
优先权日:2022-07-13
标题 :Compositions comprising surface modified globular nano-particles
发明人：ABRAMOVICH SAGI; AVIDOR GAL; LANDA BENZION
权利人:LANDA LABS 2012 LTD
摘要:There are disclosed compositions comprising core-shell nano-elements composed in their core of a water-insoluble thermoplastic compound having a molecular weight of more than 0.6 kDa and in their shell of at least one fatty amine, or a part thereof, the core-shell nano-elements having a viscosity of 107 mPa·s or less and being dispersed in a polar carrier as nano-elements having an average diameter of 200 nm or less. The water-insoluble thermoplastic compound can be capable of stimulating the synthesis of skin proteins and/or enabling the delivery of active agents upon application of the core-shell nano-elements to a surface to be treated therewith. Methods for preparing the composition and uses thereof are also provided.

专利号:US-8426643-B2
优先权日:2008-08-15
标题 :Synthesis of cyclohexane derivatives useful as sensates in consumer products

专利号:US-2014186272-A1
优先权日:2008-08-15
标题:Synthesis of cyclohexane derivatives useful as sensates in consumer products