CAS: 1693-37-4; N-(4-Hydroxyphenyl)Propionamide

上下游产品

4-amino-phenol propionic acid anhydride propionic acid N-(4-fluoro-phenyl)-propionamide N-methyl-3-nitro-anilide)acetic acid-(4-hydroxy-N-methyl-3-nitro-anilide) N-(p-propionyloxyphenyl)propionamide propionamideN-4-(2,3-epoxypropoxy)phenylpropionamide (2)1-Isopropylamino-3-(p-propionylaminophenoxy)-propanol-(2)

4-Propionamidophenyl Propionate置于sodium Hydroxide体系中,用 甲醇 用作溶剂,化学反应 24.0H,反应生成对丙胺酚
参考文献:哌啶(哌嗪)-酰胺取代的衍生物作为多靶点抗精神病药的合成和药理评价.
标题:哌啶(哌嗪)-酰胺取代的衍生物作为多靶点抗精神病药的合成和药理评价.
摘要:我们报告了与多巴胺和5-羟色胺受体的多配体方法一系列新型酰胺-哌啶(哌嗪)衍生物的优化.在衍生物中,化合物11显示出高亲和力为d 2,5-Ht 1A和5-Ht 2A受体,但低亲和性对5-Ht 2C和组胺h 2 1受体和人ether-A-Go-中间人相关基因(herg)通道.体内化合物11即使在测试的最高剂量下,阿扑吗啡引起的攀爬,Mk-801引起的活动过度和doi引起的头部抽搐也没有明显的僵直.另外,它在car测试中表现出抑制作用.此外,在一个新颖的物体识别任务中,它显示了识别属性.因此,化合物11是有希望的候选多靶点抗精神病药.
Doi:10.1016/j.Bmcl.2020.127506

专利信息

专利号:US-9006488-B1
优先权日:2014-03-20
标 题 :Solvent free synthesis of acetaminophen
发明人：AMIN MUHAMMAD; IQBAL MUHAMMAD S
权利人:AMIN MUHAMMAD; IQBAL MUHAMMAD S
摘要:A solvent-free mechanical process of reacting amine compounds with acetylating agents resulting in amides such as acetaminophen is described.

专利号:JP-2008537544-A
优先权日:2005-03-17
标题:Synthesis of abrinviramide, stephacidin B and their analogs

专利号:US-2021332001-A1
优先权日:2018-11-05
标题:Synthesis and anti-tumor activities of acyl-para-aminophenol derivatives
发明人：LALEZARI PARVIZ; LEKHARJ RUKMANI; LUNA ALEX; CASPER DIANA
权利人:MONTEFIORE MED CENTER
摘要:Method are disclosed for synthesizing derivatives of acyl-para-aminophenol and for the use of the compounds for treating lymphomas and tumors of the brain and spinal cord.

专利号:US-2015196672-A1
优先权日:2012-08-10
标 题 :Compositions, methods, and systems for the synthesis and use of imaging agents

专利号:US-2017151353-A9
优先权日:2012-08-10
标 题 :Compositions, methods, and systems for the synthesis and use of imaging agents