CAS: 18531-95-8; (S)-1,1'-Binaphthyl-2,2'-Diamine

该化合物是一种手性二胺化合物,其主脊是双硫基,广泛用于非对称合成和催化.其硬性,轴心型的手性结构使它在过渡性金属催化反应中成为宝贵的螺旋,包括对应选择性氢和C-C债券形成.该复合物具有高度立体化学稳定性和完整性,确保手感性能的一贯性能.它也被用于制作光学活性聚合物和作为手性辅助剂的先质.(S--)抗生素特别有利于其在非对称变中可预见的立体化学结果.其纯度和定义清晰的性能使它成为先进的合成应用的可靠选择.

结构式图片

欧盟法规

C&L通报

上下游产品

2-nitronaphthalene 2,2'-dinitro-[1,1']binaphthyl naphthalen-2-ylamine β-naphthol 7H-dibenzo[c,g]carbazole 1,1'-binaphthyl-2,2'-dicarboxylic acid N,N'-(1,1'-binaphthyl-2,2'-diyl)dibenzamide (S)-2,2'-diiodo-1,1'-binaphthyl

合成工艺路线路线简述

  • 合成目标产物 (S)-(-)-2,2'-Diamino-1,1'-Binaphthalene 主要起始原料 1,1'-Bi-2-Naphthol
  • (文献来源)合成步骤主要原料 1,1'-Bi-2-Naphthol

海关参考信息

专利信息


专利号:US-6469133-B2
优先权日:1999-12-13
标题 :Process for the preparation of polymers of dimeric cyclic esters
发明人:BAKER GREGORY L; SMITH III MILTON R
权利人:UNIV MICHIGAN STATE
摘要:The present invention provides a process for the direct synthesis of high melting polymers made from dimeric cyclic esters. In particular, the present invention provides a process for synthesis of polylactic acid (PLA) from racemic materials such as racemic lactide and polymandelide from mandelide. The process further provides racemic metal organic ligand catalysts such as racemic salbinap that catalyzes the polymerization of racemic dimeric cyclic ester monomers to a polylactide stereocomplex. Polymandelide and mixed dimeric cyclic esters are also prepared in the presence of low amounts of water.

专利号:US-9365494-B2
优先权日:2008-12-18
标 题 :Process for synthesis of amino-methyl tetralin derivatives
发明人:DURKIN KIERAN; FISHER LAWRENCE EMERSON; MEILI ARTHUR; SCALONE MICHAELANGELO; SHI XIANQING; VITALE JUSTIN
权利人:DURKIN KIERAN; FISHER LAWRENCE EMERSON; MEILI ARTHUR; SCALONE MICHAELANGELO; SHI XIANQING; VITALE JUSTIN; ROCHE PALO ALTO LLC
摘要:Methods for producing a compound of formula k1 or k2 n nby reducing a dihydronapthalene amide compound of formula in n nwith hydrogen gas in the presence of a ruthenium catalyst of formula j1 or j2n nRu(Z) 2 (L)  j1;n nRu(E)(E′)(L)(D)  j2;n nwherein m, n, Ar, Y, R 1 E, E′, D, Z and L are as defined herein.

专利号:WO-2007104357-A1
优先权日:2006-03-14
标 题 :Synthesis of amines with catalytic amounts of mild lewis acids
发明人:NUGENT THOMAS CHRISTOPHER; WAKCHAURE VIJAY NARAYAN; EL-SHAZLY MOHAMED MAHMOUD
权利人:UNIV JACOBS BREMEN GMBH; NUGENT THOMAS CHRISTOPHER; WAKCHAURE VIJAY NARAYAN; EL-SHAZLY MOHAMED MAHMOUD
摘要:The invention relates to methods for producing primary, secondary and tertiary amines and corresponding enantiopure or enantioenriched primary or secondary amine products, comprising the steps of reductively aminating a ketone, with a nitrogen auxiliary in the presence of a hydrogenating catalyst and a hydrogenating agent, wherein the reductive animation is performed under the influence of a mild Lewis acid, the mild Lewis acid being present at the onset of the reductive amination in at most 25 mol% of the ketone or the nitrogen auxiliary.

专利号:US-8084641-B2
优先权日:2005-10-11
标 题:Organocataslysts and methods of use in chemical synthesis
发明人:WANG WEI
权利人:WANG WEI; STC UNM
摘要:The present invention is directed to compositions comprising organocatalysts that facilitate stereo-selective reactions and the method of their synthesis and use. Particularly, the invention relates to metal-free organocatalysts for facilitation of stereo-selective reactions, and the method of their synthesis and use.

专利号:US-2013102730-A1
优先权日:2010-04-02
标 题:Polyamine-containing polymers and methods of synthesis and use
发明人:JOST ROBERT W; ULUDAG HASAN; BOLUK MEHMET YAMAN
权利人:JOST ROBERT W; ULUDAG HASAN; BOLUK MEHMET YAMAN; ALBERTA INNOVATES TECHNOLOGY FUTURES
摘要:The present invention relates to polyamine-containing polymers and methods of their synthesis and use. The polymer may be hydroxyethylcellulose, dextran, poly(vinyl alcohol) or poly(methyl acrylate).

专利号:US-7220870-B2
优先权日:1995-03-14
标 题:Hydrolytic kinetic resolution of cyclic substrates
发明人:JACOBSEN ERIC N; TOKUNAGA MAKOTO; LARROW JAY F
权利人:HARVARD COLLEGE
摘要:The present invention relates to a process for stereoselective or regioselective chemical synthesis which generally comprises reacting a nucleophile and a chiral or prochiral cyclic substrate in the presence of a non-racemic, chiral catalyst to produce a stereoisomerically- and/or regioisomerically-enriched product. The present invention also relates to hydrolytic kinetic resolutions of racemic and diastereomeric mixtures of epoxides.
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合成参考文献


摘要:Casano, G.; Ouari, O., Science of Synthesis, (2021) , 59.
摘要:Sambiagio, C.; Maes, B. U. W., Science of Synthesis: Cross-Dehydrogenative Coupling, (2023) nan, 134.
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