CAS: 189882-33-5; 6-Cyano-7-Azaindole

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1-Benzoyl-6-Cyano-7-Azaindole置于sodium Hydroxide体系中,用 甲醇 用作溶剂,化学反应 24.0H,以76%的收率获得6-氰基-7-氮杂吲哚
参考文献:Synthesis And Biological Activity Of 1H-Pyrrolo[2,3-B]Pyridine Derivatives: Correlation Between Inhibitory Activity Against The Fungus Causing Rice Blast And Ionization Potential
标题:Synthesis And Biological Activity Of 1H-Pyrrolo[2,3-B]Pyridine Derivatives: Correlation Between Inhibitory Activity Against The Fungus Causing Rice Blast And Ionization Potential
摘要:Synthesis And Biological Activity Of A Variety Of 3-And B-Substituted 1H-Pyrrolo[2,3-B]Pyridine (7-Azaindole) Derivatives Are Described. Many Of The Synthesized 7-Azaindoles Exhibited Considerable Fungicidal Activity Toward Pyricularia Oryzae,A Fungus Which Causes Rice Blast,In Vivo. When Quantum Parameters Of The Tested 7-Azaindoles Were Evaluated By Semiempirical Molecular Orbital Calculations,A Relationship Was Observed Between The Activity And The Calculated Ionization Potentials Of The 7-Azaindole Derivatives.
Doi:10.1021/jf9607730