CAS: 19355-69-2; 2-Amino-2-Methylpropanenitrile

相似化合物

50846-36-1 1936001-61-4 133117-97-2

上下游产品

CAS号75-86-5 丙酮氰醇 | CAS号143-33-9 氰化钠 | CAS号67-64-1 丙酮 | CAS号773837-37-9 sodium cyanide | CAS号151-50-8 氰化钾 | CAS号126-98-7 甲基丙烯腈 | CAS号74-90-8 氢氰酸 | CAS号75-15-0 二硫化碳 | CAS号2273-39-4 2-Methyl-2-(met... | CAS号74-89-5 氨基甲烷 | CAS号1113-49-1 2-氨基-2-甲基丙酸乙酯 | CAS号50846-36-1 2-氨基-2-甲基丙腈盐酸盐 | CAS号2273-41-8 α,α-二甲基-1-哌啶乙腈 | CAS号75-31-0 异丙胺 | CAS号64-18-6 甲酸 | CAS号74-90-8 氢氰酸 | CAS号7664-41-7 氨 | CAS号35666-81-0 4-(4-(4-(三氟甲基)苯... | CAS号80-62-6 甲基丙烯酸甲酯 | CAS号2582-16-3 4-Imidazolidine...

氰化钾置于氯化铵体系中,化学反应生成N-氰基-N'-甲基乙脒
参考文献:Zelinsky; Stadnikow,Chemische Berichte,1906,Vol. 39,P. 1726
标题:Zelinsky; Stadnikow,Chemische Berichte,1906,Vol. 39,P. 1726

专利信息

专利号:US-9475799-B1
优先权日:2011-12-26
标 题 :Synthesis of Raltegravir
发明人：GURJAR MUKUND KESHAV; SONAWANE SWAPNIL PANDITRAO; MAIKAP GOLAKCHANDRA SUDARSHAN; PATIL GULABRAO DAGADU; SHINDE SHIVNATH BHAUPATIL; SHALIKRAO PANKAJ; MEHTA SAMIT SATISH
权利人:EMCURE PHARMACEUTICALS LTD
摘要:The present invention relates to a novel synthetic route for the preparation of raltegravir and pharmaceutically acceptable salts, starting from 2-amino-2-methylpropanenitrile and oxadiazole carbonyl chloride, through the formation of a pyrimidinone intermediate of formula (V).

专利号:US-7179918-B2
优先权日:2001-06-11
标 题:HIV protease inhibitors, compositions containing the same, their pharmaceutical uses and materials for their synthesis
发明人：CANAN KOCH STACIE S; ALEXANDER THERESE N; BURKE BENJAMIN J; JEWELL TANYA M; KUCERA DAVID J; LINTON MARIA ANGELICA; MITCHELL JR LENNERT J; REICH SIEGFRIED H; SKALITZKY DONALD J; TATLOCK JOHN H; VARNEY MICHAEL D; VIRGIL SCOTT C; WEBBER STEPHEN E; WORLAND STEPHEN T; BARVIAN MARK; BOLTON GARY; BOYER JR FREDERICK EARL; MACHAK JEFFREY J; HOLLER TOD; MURPHY SEAN T; MELNICK MICHAEL; JOSYULA VARA PRASAD
权利人:AGOURON PHARMA
摘要:Compounds of the formula: n nwhere the formula variables are as defined herein, are disclosed that advantageously inhibit or block the biological activity of the HIV protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with the HIV virus. Intermediates and synthetic methods for preparing such compounds are also described.

专利号:EP-3686190-A1
优先权日:2013-07-11
标 题 :Synthesis of therapeutically active compounds

专利号:US-2015045554-A1
优先权日:2011-12-26
标题:Synthesis of raltegravir

专利号:EP-2804607-B1
优先权日:2011-12-26
标题:Synthesis of raltegravir

专利号:US-2016311810-A1
优先权日:2011-12-26
标题:Synthesis of raltegravir