CAS: 224185-19-7; 4-Bromo-5-Fluoro-2-Nitrotoluene

上下游产品

CAS号452-74-4 3-氟-4-溴甲苯 | CAS号259860-00-9 2-氟-4-甲基-5-硝基苯胺 | CAS号446-33-3 5-氟-2-硝基甲苯 | CAS号7787-70-4 溴化亚铜 | CAS号627871-16-3 5-溴-4-氟-2-甲基苯胺 | CAS号1226903-72-5 6-溴-5-乙氧基-1H-吲唑

5-氟-2-硝基甲苯置于硫酸,溴,Silver Nitrate体系中,用 (2S)-N-Methyl-1-Phenylpropan-2-Amine Hydrate 用作溶剂,以83%的收率获得4-溴-5-氟-2-硝基甲苯
参考文献:Heterocyclic Compounds Having Nos Inhibitory Activities
标题:Heterocyclic Compounds Having Nos Inhibitory Activities
摘要:通式(1)所表示的化合物:[其中r1通常是氨基烷基团;R2通常是氢原子,低烷基团,R3或sr4(其中r4通常是低烷基团);Ar通常是5-成员芳香杂环基团]具有nos抑制活性,并可用作脑血管疾病和其他药物的治疗剂.

专利信息

专利号:US-7563900-B2
优先权日:2004-10-13
标 题:Process for the preparation N-(3,5-dichloropyrid-4-yl)-4-difluoromethoxy-8-methane sulfonamido-dibenzo[b,d]furan-1-carboxamide
发明人：GOPALAN BALASUBRAMANIAN; GHARAT LAXMIKANT A; CHANDRASEKHAR BATCHU; PILLAI BIJUKUMAR G
权利人:GLENMARK PHARMACEUTICALS SA
摘要:The present invention relates to a method of preparing N-(3,5-dichloropyrid-4-yl)-4-difluoromethoxy-8-methanesulfonamido-dibenzo[b,d]furan-1-carboxamide and pharmaceutically acceptable salts thereof, such as its sodium salt, and novel intermediate compounds useful in the synthesis of the aforementioned compound.

专利号:CN-118598751-A
优先权日:2024-05-31
标 题 :Synthesis method of 5-bromo-1-fluoro-3-methyl-2-nitrobenzene