CAS: 618-45-1; 3-Isopropylphenol

该化合物是一种有机化合物,其特点是含有异丙基化合物的酚结构,其异丙基化合物组附于苯环的副位置,其分子式为C10H14O,其特性为氢氧(-OH)功能组,具有典型的苯异质特性.该化合物无色可粉黄,具有典型的气味,在水中表现出有限的溶解性,在有机溶剂中可溶解. 3-异丙基苯醇因其抗微生物和抗氧化性特性而闻名,在各种应用中有用,包括在化妆品和个人护理产品中作为防腐蚀剂.此外,它还可以作为其他化学化合物合成的中间体.安全考虑包括潜在的皮肤和眼刺激,应当采取适当的处理措施以尽量减少接触.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号99-62-7 1,3-二异丙基苯 | CAS号75-30-9 2-碘代丙烷 | CAS号626-02-8 3-碘苯酚 | CAS号187737-37-7 propene | CAS号108-95-2 苯酚 | CAS号98-82-8 异丙基苯 | CAS号6380-20-7 3-isopropylanisole | CAS号6526-74-5 间异丙基硝基苯 | CAS号5369-16-4 3-异丙基苯胺 | CAS号181035-65-4 2-methoxy-4-pro... | CAS号1878-52-0 2-(3-propan-2-y... | CAS号88-69-7 2-异丙基苯酚 | CAS号2934-05-6 2,4-二异丙基苯酚 | CAS号2934-07-8 2,4,6-tri(propa... | CAS号35946-91-9 2,5-二异丙基苯酚 | CAS号25238-25-9 Benzenesulfonic... | CAS号99-89-8 4-异丙基苯酚 | CAS号1017608-20-6 4-碘-3-异丙基苯酚 | CAS号1017608-23-9 2-iodo-5-isopro...

合成工艺路线路线简述

  • 合成目标产物 3-Isopropylphenol 主要起始原料 3-Isopropylaniline
  • (文献来源)合成步骤主要原料 3-Isopropylaniline
香芹酚置于盐酸,氢氧化钾体系中,化学反应生成 3-异丙基苯酚
参考文献:Jacobsen,Chemische Berichte,1878,Vol. 11,P. 1059
标题:Jacobsen,Chemische Berichte,1878,Vol. 11,P. 1059

海关参考信息

专利信息


专利号:US-6815214-B2
优先权日:2000-12-29
标 题 :Pharmaceutical uses and synthesis of diketopiperazines
发明人:BOYCE JIM P; HOWBERT J JEFFRY; TABONE JOHN C
权利人:CELLTECH R & D INC
摘要:The synthesis of novel diketopiperazines, their use in inhibiting cellular events such as those involving NFK-α, NFK-β and in the treatment of inflammation events, a combinatorial library of diverse diketopiperazines and process for their synthesis as a library and as individual compounds. In particular novel diketopiperazines are disclosed including their synthesis and use in cellular events such as activation of the transcription factor, nuclear factor, TNF-α, TNF-β and also apoptosis.

专利号:US-10040752-B2
优先权日:2015-08-24
标 题 :Synthesis of levomethadone hydrochloride or dextromethadone hydrochloride and methods for use thereof
发明人:MKRTCHYAN GNEL; YAO QINGWEI
权利人:CODY LABORATORIES INC
摘要:Highly efficient methods for synthesis of levomethadone hydrochloride or dextromethadone hydrochloride are provided starting from D-alanine, or L-alanine, respectively, with retention of configuration. Methods for treating a subject are provided comprising administering a composition comprising an effective amount of levomethadone hydrochloride having not more than 10 ppm dextromethadone.

专利号:US-2004110228-A1
优先权日:2002-04-01
标 题:Combinatorial organic synthesis of unique biologically active compounds
发明人:MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.

专利号:US-5663480-A
优先权日:1993-12-20
标题:Synthesis of aromatic carbonates by transesterification using a catalyst comprising a microporous material and a group IV metal
发明人:TSUNEKI HIDEAKI; KIRISHIKI MASARU; WATANABE KENICHI; ONDA YOSHIYUKI
权利人:NIPPON CATALYTIC CHEM IND
摘要:A catalyst for producing an aryl ester of a carbonic or carboxylic acid is disclosed, which includes a microporous material containing a metal element belonging to group IV. This catalyst can be used as a heterogeneous catalyst to produce the aryl ester in high yield with industrial advantages. In order to produce the aryl ester using the catalyst, a carbonate or an aliphatic carboxylate is transesterified with an aromatic hydroxy compound, or an aryl carboxylate is transesterified with a carbonate, or an alkyl aryl carbonate is disproportionated by transesterification.

专利号:US-4161609-A
优先权日:1977-09-14
标题:Synthesis of carboxylic acid esters
发明人:CRAMER RICHARD D
权利人:DU PONT
摘要:A method is provided for converting a carboxylic acid amide to a carboxylic acid ester by reacting a vaporized mixture of the amide and an aliphatic alcohol or a phenol in the presence of a suitable catalyst at temperatures of from 100 DEG C. to 400 DEG C. The process is especially useful for the conversion of methacrylamide to methyl methacrylate.

专利号:US-4665238-A
优先权日:1985-01-22
标题 :Process for the synthesis of alkylaromatic compounds
发明人:IMAI TAMOTSU; BARGER PAUL T
权利人:UOP INC
摘要:Alkylaromatic compounds may be synthesized by reacting an aromatic compound with an alkylating agent comprising a mixture of gases, including carbon monoxide and hydrogen at alkylation conditions in the presence of a dual-function-catalyst. The catalyst system which is employed for this reaction will comprise (1) a composite of oxides of copper and chromium and (2) an aluminosilicate which may be either in crystalline or amorphous form.
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合成参考文献


摘要:González-Bello, C., Science of Synthesis Knowledge Updates, (2018) 1, 211.
摘要:Allen, C. C. R., Science of Synthesis: Biocatalysis in Organic Synthesis, (2015) 3, 9.
摘要:Selt, M.; Waldvogel, S. R., Science of Synthesis: Special Topics, (2021) 1, 262.
摘要:P. Demerseman, J. P. Lechartier, R. Reynaud, A. Cheutin, R. Royer and P. Rumpf, Bull. Soc. Chim. Fr. 1963, 2559.
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