CAS: 626-23-3; Di-Sec-Butylamine

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CAS号78-93-3 甲乙酮 | CAS号33966-50-6 丁胺 | CAS号38836-40-7 N-2-butylidene-... | CAS号106-98-9 正丁烯 | CAS号96-29-7 2-丁酮肟 | CAS号78-92-2 仲丁醇 | CAS号78-76-2 溴代仲丁烷 | CAS号1129-62-0 苯腙-2-丁酮 | CAS号51608-96-9 N-2,6-Dimethylp... | CAS号1333-74-0 氢 | CAS号121-44-8 三乙胺 | CAS号27922-66-3 N,N-di(butan-2-... | CAS号100-61-8 N-甲基苯胺 | CAS号33966-50-6 丁胺 | CAS号32322-33-1 N,N-DI-SEC-BUTY... | CAS号78-93-3 甲乙酮 | CAS号36756-79-3 仲草丹

仲丁醇置于碳酸氢铵体系中,用 5,5-Dimethyl-1,3-Cyclohexadiene 作为反应溶剂,化学反应 24.0H,以73%的收率获得产物二仲丁胺
参考文献:研发一种用于胺和氨的醇类良性胺化的通用非贵金属催化剂
标题:研发一种用于胺和氨的醇类良性胺化的通用非贵金属催化剂
摘要:胺或氨与醇的n-烷基化是合成n-烷基胺的一条有价值的途径.但是,作为n-烷基胺合成的潜在清洁和经济选择,极少报道具有高活性和非常好选择性的非贵金属催化剂.通常,由于活动量低和通用性差,它们受到严格限制.这里,简单的nicufeo X设计并制备了用于将氨或胺与醇或伯胺进行n-烷基化的催化剂.在没有有机配体和碱的情况下,成功合成了具有各种结构的n-烷基胺,产率中等至优异.通常,伯胺可以有效地转化为仲胺和n-杂环化合物,仲胺可以被n-烷基化以合成叔胺.请注意,伯氨和仲胺可以通过氨和醇的一锅法反应反应生成.除了优异的催化性能外,催化剂本身还具有出色的优越性,即对空气和湿气稳定.而且,
DOI:10.1002/chem.201203417

专利信息

专利号:US-11161827-B2
优先权日:2019-04-05
标 题 :Catalytic systems for stereoselective synthesis of chiral amines by enantiodivergent radical C—H amination
发明人：Zhang xiao-xiang; Lang kai
权利人:TRUSTEES BOSTON COLLEGE; THE TRUSTEES OF BOSTON COLLEGE
摘要:In one aspect, the disclosure relates to a mode of asymmetric induction in radical processes based on sequential combination of enantiodifferentiative H-atom abstraction and stereoretentive radical substitution. Also disclosed is an asymmetric system for stereoselective synthesis of strained 5-membered cyclic sulfamides via radical 1,5-C—H amination of sulfamoyl azides. The disclosed metalloradical system can control the degree and sense of asymmetric induction in the catalytic radical C—H amination in a systematic manner. The disclosed system is applicable to a broad scope of substrates with different types of C(sp 3 )—H bonds and exhibits reactivity and selectivity, providing access to both enantiomers of useful 5-membered cyclic sulfamides in a highly enantioenriched form. Also disclosed are catalysts useful in these processes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

专利号:US-11059914-B2
优先权日:2016-12-21
标题:Method for the continuous synthesis of a diene elastomer with lithium amide initiator
发明人：DIRE CHARLOTTE; DESSENDIER MARIE-HÉLÈNE
权利人:MICHELIN & CIE
摘要:A process for the continuous synthesis of a diene elastomer is provided. The synthesis is conducted by means of n reactors r1 to rn, considered to be continuous stirred-tank reactors, which are equipped with an internal stirring system. The reactors are arranged in series, n varying from 2 to 15, preferably from 2 to 9. The reactor r1 is fed by an input solution comprising a solvent, one or more monomer(s), an anionic polymerization initiator chosen from lithium amides and a polar agent. The conversion by weight C1 in the first reactor is less than 70%, and the total conversion by weight Cn at the outlet of the reactor rn is greater than or equal to 70%.

专利号:US-11912647-B2
优先权日:2020-05-22
标 题:Diversity-oriented synthesis of N,N,O-trisubstituted hydroxylamines from alcohols and amines by N—O bond formation
发明人：CRICH DAVID; HETTIKANKANAMALAGE ASIRI; HILL JARVIS
权利人:UNIV GEORGIA
摘要:In one aspect, the disclosure relates to a method for the direct synthesis of complex N,N,O-trisubstituted hydroxylamines by N—O bond formation. In another aspect, the method can successfully be employed using a wide variety of commercially available alcohols and secondary amines and enables the construction of large fragment-based libraries of trisubstituted hydroxylamines for drug discovery purposes. Also disclosed are N,N,O-trisubstituted hydroxylamines having low basicity, high stability at ambient temperatures, and an inherent lack of reactivity towards acetylating and sulfonylating enzymes that confer mutagenicity on less-substituted hydroxylamines.

专利号:US-4472568-A
优先权日:1981-11-12
标 题:Process for the preparation of polyamines from N-monoaryl-N',N'-dialkyl urea compounds and their use for the synthesis of polyurethanes
发明人：RASSHOFER WERNER; GROEGLER GERHARD
权利人:BAYER AG
摘要:This invention relates to an improved process for the preparation of aromatic polyamines containing urethane and/or biuret and/or urea and/or isocyanurate groups and preferably also ether groups by the hydrolysis of poly-N-monoaryl-N',N'-dialkyl urea compounds (1-aryl-3,3-dialkyl ureas). The ureas are obtained by the reaction of secondary aliphatic, cycloaliphatic or saturated heterocyclic amines with divalent to tetravalent isocyanate compounds containing isocyanate end groups attached to aromatic residues. The ureas correspond to the general formula: wherein R1, R2 denote alkyl or cycloalkyl groups, or together form a ring and A denotes a divalent to tetravalent residue attached to the ureas by aromatic groups. Hydrolysis is carried out in the presence of water and up to two equivalents of a base containing hydroxide ions and/or up to two equivalents of a compound containing tertiary amino groups, optionally in the presence of solvents. The use of the polyamines obtained by this process for the synthesis of polyurethanes is also described.

专利号:US-6271375-B1
优先权日:1997-06-30
标 题 :Ortho-metalation process for the synthesis of 2-substituted-1-(tetrazol-5-yl)benzenes
发明人：VILLA MARCO; ALLEGRINI PIETRO; ARRIGHI KATIUSCIA; PAIOCCHI MAURIZIO
权利人:ZAMBON SPA
摘要:A process of direct metalation of phenyltetrazoles useful for preparing compounds of formula (II) intermediates for the synthesis of angiotensin II antagonists is described.

专利号:US-6987186-B2
优先权日:2003-01-28
标 题 :Synthesis of small particle size quinacridone of beta crystal phase
发明人：COLE DAMIEN THURBER; JEGANATHAN SURULIAPPA GOWDER; HE YINGXIA
权利人:CIBA SC HOLDING AG
摘要:The present invention relates to a process for the synthesis of beta-quinacridone by oxidation in the presence of selected additives that promote the formation of the desired crystal phase and particle size.