CAS: 81-23-2; (R)-4-((5S,8R,9S,10S,13R,14S,17R)-10,13-Dimethyl-3,7,12-Trioxohexadecahydro-1H-Cyclopenta[a]Phenanthren-17-yl)Pentanoic Acid

相似化合物

2304-91-8 2458-08-4 517-33-9

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CAS号81-25-4 胆酸 | CAS号361-09-1 胆酸钠 | CAS号1100696-11-4 (24RS,25RS)-3α,... | CAS号64-19-7 冰醋酸 | CAS号7726-95-6 溴素 | CAS号7732-18-5 水 | CAS号1061-64-9 (3a,5b,7a,12a)-... | CAS号81-25-4 胆酸 | CAS号2304-89-4 3-氧代-7a,12a-二羟基... | CAS号153222-72-1 7α,12β-dihydrox... | CAS号87-91-2 L-(+)-酒石酸二乙酯 | CAS号52718-49-7 ethyl 3,7,12-tr... | CAS号5739-38-8 1-(4-methoxyphe... | CAS号1553-56-6 3-Oxo-5β-cholan...

Sodium Scymnol Sulfate置于chromium(Vi) Oxide体系中,用 水,溶剂黄146 作为反应溶剂,化学反应 5.0H,以90 Mg的收率获得产物去氢胆酸
参考文献:尖吻根霉胆汁盐薄荷油硫酸钠的研究.
标题:尖吻根霉胆汁盐薄荷油硫酸钠的研究.
摘要:从5个胆囊(65克)中通过3步色谱法分离出753毫克的胆盐,主要成分为锐齿镰鳐(rhizoprionodon Acutus)胆汁中的硫酸钠胸腺醇,其结构根据化学和物理数据被确定为3α,7α,12α,24,26-五羟基-5β-胆甾烷-27-基硫酸钠.
DOI:10.1248/cpb.36.4408

专利信息

专利号:US-2012190064-A1
优先权日:2004-10-01
标题 :Feeding buffers, systems, and methods for in vitro synthesis of biomolecules
发明人：KUDLICKI WIESLAW ANTONI; KEPPETIPOLA SHIRANTHI; FLETCHER JULIA; GETBEHEAD ASHLEY ELAINE; KATZEN FEDERICO; VOZZA-BROWN LAURA
权利人:KUDLICKI WIESLAW ANTONI; KEPPETIPOLA SHIRANTHI; FLETCHER JULIA; GETBEHEAD ASHLEY ELAINE; KATZEN FEDERICO; VOZZA-BROWN LAURA; LIFE TECHNOLOGIES CORP
摘要:Compositions, methods and kits for in vitro systems for synthesis of biomolecules such as polypeptides, are provided herein. Cell extracts that provide enhanced yields of soluble proteins using in vitro protein synthesis methods are provided. The invention also includes methods for producing high yields of proteins by the addition of a feeding solution that includes amino acids and an energy source to an ongoing in vitro synthesis system. The invention also includes methods of using a high-yield in vitro synthesis system to produce large quantities of proteins with incorporated labeled amino acids for analysis by methods such as by NMR. The invention further includes vectors for enhanced production of proteins from nucleic acid templates using in vitro synthesis systems.

专利号:WO-2004011474-A1
优先权日:2002-07-31
标题:Universal support media for synthesis of oligomeric compounds
发明人：GUZAEV ANDREI P; MANOHARAN MUTHIAH; RAVIKUMAR VASULINGA T; KUMAR RAJU K
权利人:ISIS PHARMACEUTICALS INC; GUZAEV ANDREI P; MANOHARAN MUTHIAH; RAVIKUMAR VASULINGA T; KUMAR RAJU K
摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotide and oligonucleotide mimetics, are provided. In addition, methods for functionalizing a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.

专利号:US-6653468-B1
优先权日:2002-07-31
标 题 :Universal support media for synthesis of oligomeric compounds
发明人：GUZAEV ANDREI P; MANOHARAN MUTHIAH
权利人:ISIS PHARMACEUTICALS INC
摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotides and oligonucleotide mimetics, are provided. In addition, methods for functionalizing a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.

专利号:US-5688941-A
优先权日:1990-07-27
标题:Methods of making conjugated 4' desmethyl nucleoside analog compounds
发明人：COOK PHILLIP DAN; TENG KELLY
权利人:ISIS PHARMACEUTICALS INC
摘要:Tetrahydrofuranyl compounds are provided that are functionalized to include pendant conjugate groups, and which are useful in diagnostic assays and as research reagents. Novel intermediates for the synthesis of the compounds are also provided.

专利号:US-10544441-B2
优先权日:2014-06-24
标 题 :Method for biocatalytic whole cell reduction of dehydrocholic acid compounds, and 7-β-hydroxysteroid dehydrogenase mutants
发明人：WEUSTER-BOTZ DIRK; SUN BOQIAO; QUIRIN CHRISTIAN
权利人:PHARMAZELL GMBH
摘要:The invention relates to novel biocatalytic processes comprising the whole cell reduction of dehydrocholic acid (DHCA) compounds, novel 7β-hydroxy steroid dehydrogenase mutants, the sequences coding for these enzyme mutants, methods for producing the enzyme mutants and use thereof in enzymatic conversions of cholic acid compounds, and in particular in the production of ursodesoxycholic acid (UDCA); also a subject of the invention are novel methods for the synthesis of UDCA using the enzyme mutants; and in particular a further improved method for producing UDCA using recombinant whole cell biocatalysts.

专利号:US-11306343-B2
优先权日:2014-08-12
标 题:3α-hydroxysteroid dehydrogenase mutants and process for the preparation of ursodeoxycholic acid
发明人：HUMMEL WERNER; BAKONYI DANIEL
权利人:PHARMAZELL GMBH
摘要:The invention provides novel 3α-hydroxysteroid dehydrogenase mutants, sequences that code for these enzyme mutants, methods for producing the enzyme mutants, and the use thereof in enzymatic reactions of cholic acid compounds, and in particular in the production of ursodeoxycholic acid (UDCA). The invention further provides processes for the synthesis of UDCA using the enzyme mutants and the production of UDCA using recombinant microorganisms that have been subjected to multiple modifications.