CAS: 120-25-2; 4-Ethoxy-3-Methoxybenzaldehyde

该化合物是属于芳香藻类的有机化合物,其特征为苯环,与乙氧组和甲氧组以及甲氧功能组一起被替换,该化合物一般是一种无色的黄色液体或固态,视温度和纯度而定.该化合物具有典型的芳香味,在藻类中很常见.乙氧基和甲氧基子成分的存在影响其溶解性,使其在有机溶剂中比在水中更容易溶解.4-乙氧-3-甲氧基苯甲酰胺经常用于有机合成,并用作各种制药和农业化学品生产的中间体.该化合物的再活性主要归因于甲醚组,该组可以参与各种化学反应,包括凝聚和氧化.在处理该化合物时,应当采取安全防范措施,因为它可能导致皮肤和眼睛受到刺激.

结构式图片

相似化合物

61813-58-9 1131-52-8 1131-52-8

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号74-96-4 溴乙烷 | CAS号121-33-5 香草醛 | CAS号64-67-5 硫酸二乙酯 | CAS号139-85-5 原儿茶醛; 原二茶醛; 茶酚甲... | CAS号2539-53-9 4-乙氧基-3-羟基苯甲醛 | CAS号74-88-4 碘甲烷 | CAS号75-03-6 碘乙烷 | CAS号74368-00-6 Eugenyl ethyl ether | CAS号77-78-1 硫酸二甲酯 | CAS号97692-56-3 Ethyl vanillyl ... | CAS号103095-48-3 4-乙氧基-5-甲氧基-2-硝基苯甲酸 | CAS号103095-41-6 (6ci)-4-乙氧基-5-甲... | CAS号54503-18-3 3-氨基-3-(4-乙氧基-3... | CAS号144878-40-0 (E)-3-(4-乙氧基-3-... | CAS号121-33-5 香草醛 | CAS号3535-30-6 4-乙氧基-3-甲氧基苯甲酸 | CAS号2539-53-9 4-乙氧基-3-羟基苯甲醛 | CAS号103796-34-5 4,5-二乙氧基-2-硝基苯甲酸 | CAS号33963-27-8 1-ethoxy-2-meth... | CAS号120-13-8 4-乙氧基-3-甲氧基苯乙酸

合成工艺路线路线简述

    乙基香草基碳酸酯 反应生成4-乙氧基-3-甲氧基苯甲醛
    参考文献:Rosenmund; Dornsaft,Chemische Berichte,1919,Vol. 52,P. 1742
    标题:Rosenmund; Dornsaft,Chemische Berichte,1919,Vol. 52,P. 1742

    海关参考信息

    专利信息


    专利号:US-5763681-A
    优先权日:1989-09-06
    标 题 :Synthesis of stable, water-soluble chemiluminescent 1,2-dioxetanes and intermediates therefor
    发明人:EDWARDS BROOKS; JUO RHOU-RONG
    权利人:TROPIX INC
    摘要:A novel synthesis of compound having the formula: ##STR1## wherein T is a stabilizing spiro-linked polycycloalkylidene group, R 3 is a C 1 -C 20 alkyl, aralkyl or heteroatom containing group, Y is an aromatic fluorescent chromophore, and Z is a cleavable group which, when cleaved, induces decomposition of the dioxetane ring and emission of optically detectable light, is disclosed. A tertiary phosphorous acid alkyl ester of the formula: n n (R.sup.1 O).sub.3 P n n wherein R 1 is a lower alkyl group, is reacted with an aryl dialkyl acetal produced by reacting a corresponding aryl aldehyde with an alcohol of the formula: n n R.sup.3 OH n n wherein R 3 is as defined above, to produce a 1-alkoxy-1-aryl-methane phosphonate ester of the formula: ##STR2## reacting the phosphonate with base to produce a phosphonate-stabilized carbanion, reacting the carbanion with a ketone of the formula: ##STR3## wherein T is as defined above, to produce an enol ether of the formula: ##STR4## then oxygenating the double bond in the enol ether to give the corresponding 1,2-dioxetane compound.

    专利号:US-8957230-B2
    优先权日:2011-06-30
    标 题 :Synthesis of cleistanthin A and derivatives thereof
    发明人:MULIK NILESH SHRIDHAR; PANGHAVANE KAILASH DATTATRAYA
    权利人:MULIK NILESH SHRIDHAR; PANGHAVANE KAILASH DATTATRAYA
    摘要:The present invention provides a method for preparing Cleistanthin A, a diphyllin glycoside, derivatives thereof and intermediates thereto. In particular the present invention provides in one of the aspect a method for synthesis of compound of formula D a key intermediate of diphyllin, which can be carried out in a shorter duration and at an ordinary temperature.

    专利号:US-9597327-B2
    优先权日:2005-05-25
    标 题:Synthesis of (R)-N-methylnaltrexone
    发明人:DOSHAN HAROLD D; PEREZ JULIO
    权利人:PROGENICS PHARM INC
    摘要:This invention relates to stereoselective synthesis of R-MNTX and intermediates thereof, pharmaceutical preparations comprising R-MNTX or intermediates thereof and methods for their use.

    专利号:US-5175302-A
    优先权日:1987-07-13
    标 题 :Nucleophilic fluoroalkylation of aldehydes
    发明人:STAHLY G PATRICK
    权利人:ETHYL CORP
    摘要:Aryl difluoromethyl sulfone adds to aldehydes under phase transfer conditions to give novel substituted alcohols of the general formula n n RCH(OH)CF.sub.2 SO.sub.2 Ar (I) n n wherein R is an aryl, cycloaliphatic, sec- or tert-aliphatic, or heterocyclic group and Ar is an aryl group. The substituted alcohols of formula I are of particular utility as intermediates in the synthesis of a variety of useful end products. For example, the products of formula I may be utilized in desulfonylation reactions, oxidation reactions and fluorination reactions.

    专利号:US-4837327-A
    优先权日:1987-07-13
    标 题 :Process for nucleophilic fluoroalkylation of aldehydes
    发明人:STAHLY G PATRICK
    权利人:ETHYL CORP
    摘要:Aryl difluoromethyl sulfone adds to alkehydes under phase transfer conditions to give novel substituted alcohols of the general formula n n RCH(OH)CF.sub.2 SO.sub.2 Ar (I) n n wherein R is an aryl, cycloaliphatic, sec- or tert-aliphatic, or heterocyclic group and Ar is an aryl group. The substituted alcohols of formula I are of particular utility as intermediates in the synthesis of a variety of useful end products. For example, the products of formula I may be utilized in desulfonylation reactions, oxidation reactions and fluorination reactions.

    专利号:US-4999429-A
    优先权日:1989-01-09
    标 题 :Process for the preparation of α,α,β-1-trifluoro-1-olefinic derivatives
    发明人:STAHLY G PATRICK
    权利人:ETHYL CORP
    摘要:Aryl difluoromethyl sulfone adds to aldehydes under phase transfer conditions to give novel substituted alcohols of the general formula n n RCH(OH)CF.sub.2 SO.sub.2 Ar (I) n n wherein R is an aryl, cycloaliphatic, sec- or tert-aliphatic, or heterocyclic group and Ar is an aryl group. The substituted alcohols of formula I are of particular utility as intermediates in the synthesis of a variety of useful end products. For example, the products of formula I may be utilized in desulfonylation reactions, oxidation reactions and fluorination reactions.
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    主要参考文献

    参考标题:Transaminase-Mediated Synthesis Of Enantiopure Drug-Like 1-(3′,4′-Disubstituted Phenyl)Propan-2-Amines
    作者:ágnes Lakó,Zsófia Molnár,Ricardo Mendonça,László Poppe
    摘要:Transaminases (Tas) Offer An Environmentally And Economically Attractive Method For The Direct Synthesis Of Pharmaceutically Relevant Disubstituted 1-Phenylpropan-2-Amine Derivatives Starting From Prochiral Ketones. In This Work, We Report The Application Of Immobilised Whole-Cell Biocatalysts With (R)-Transaminase Activity For The Synthesis Of Novel Disubstituted 1-Phenylpropan-2-Amines. After Optimisation

    合成参考文献


    摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198
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