专利号:US-9867899-B2 优先权日:2010-05-24 标题 :Reinforced adhesive complex coacervates and methods of making and using thereof 发明人:STEWART RUSSELL J 权利人:UNIV UTAH RES FOUND 摘要:Described herein is the synthesis of reinforced adhesive complex coacervates and their use thereof. The reinforced adhesive complex coacervates are composed of (a) at least one polycation, (b) at least one polyanion, and (c) a reinforcing component. The adhesive complex coacervates described herein can be subsequently cured to produce strong, cohesive adhesives. The reinforced adhesive complex coacervates have several desirable features when compared to conventional adhesives. The reinforced adhesive complex coacervates are effective in wet or underwater applications. The reinforced adhesive complex coacervates described herein, being phase separated from water, can be applied underwater without dissolving or dispersing into the water. The reinforced adhesive complex coacervates have numerous biological applications as bioadhesives and bioactive delivery devices. In particular, the reinforced adhesive complex coacervates described herein are particularly useful in underwater applications and situations where water is present such as, for example, wet tissues in physiological conditions.
专利号:US-2014220082-A1 优先权日:2011-06-28 标 题:Adhesive complex coacervates and methods of making and using thereof 发明人:STEWART RUSSELL J 权利人:STEWART RUSSELL J; UNIV UTAH RES FOUND 摘要:Described herein is the synthesis of adhesive complex coacervates and their use thereof. The adhesive complex coacervates are produced by reacting (a) at least one poly anion comprising a plurality of activated ester groups, and (b) at least one polycation comprising a plurality of nucleophilic groups, wherein the nucleophilic groups react with the activated ester groups to produce a new oovalent bond between the polycation and the polyanion. The adhesive complex coacervates described herein have low interfacial tension with water and wettable substrates. When applied to a wet substrate they spread over the interface rather than beading up. The adhesive complex coacervates have numerous biological applications as bioadhesives and drug delivery devices. In particular, the adhesive complex coacervates described herein are particularly useful in wet or underwater applications and situations where water is present such as, for example, physiological conditions.
专利号:US-4405523-A 优先权日:1982-03-24 标题:Process for preparation of benzophenone, anthraquinone and O-dibenzoylbenzene 发明人:FIELDS ELLIS K 权利人:STANDARD OIL CO INDIANA 摘要:Process for the concurrent synthesis of benzophenone, anthraquinone, and o-dibenzoylbenzene by pyrolysis of benzoic acid salts of yttrium, erbium, and dysprosium and mixtures thereof at temperatures of from about 200 DEG C. to 500 DEG C. and a pressure of about 0.1 to about 100 atmospheres. In an alternative method, a benzoic acid compound is passed through an oxide of yttrium, erbium, dysprosium and mixtures thereof in the presence of steam.
专利号:US-9359396-B2 优先权日:2011-07-12 标题:Material for supported synthesis and method for growing oligonucleotides or peptides 发明人:CHAIX CAROLE; DE CROZALS GABRIEL; FARRE CAROLE 权利人:CHAIX CAROLE; DE CROZALS GABRIEL; FARRE CAROLE; UNIV CLAUDE BERNARD LYON; CENTRE NAT RECH SCIENT 摘要:The invention concerns a material composed of a porous support on which functionalized nanoparticles are grafted by covalent bonding, characterized in that at least part of the nanoparticles grafted by covalent bonding is housed inside surface pores of the support, and in that the support is silica-based and is in the form of porous particles of heterogeneous shape and size, the size of the particles being larger than 1 μm and preferably within the range of 5 to 200 μm. n The invention further concerns a growth method for oligonucleotides or peptides characterized in that growth is performed on a material formed of a porous support on which functionalized nanoparticles are grafted by covalent bonding, characterized in that at least a part of the nanoparticles grafted by covalent bonding is housed inside surface pores of the support.
专利号:US-2011104052-A1 优先权日:2007-12-03 标 题 :Methods of synthesis and use of chemospheres 发明人:BARNETT BRADLEY POWERS; GESCHWIND JEFFREY 权利人:UNIV JOHNS HOPKINS 摘要:The present invention provides, in general, compositions comprising a hydrogel and an agent, for example a therapeutic agent or an imaging agent, for locoregional delivery. In certain preferred embodiments of the invention, the hydrogel compositions are detectable by Magnetic Responance and CT Scan and are used for locoregional delivery of therapeutic agents, for example chemotherapeutic agents. The invention also features polymer matrix compositions comprising nanoparticles that can be loaded after polymerization with bioactive agents, for example a diagnostic agent or therapeutic agent.
专利号:US-9394480-B2 优先权日:2012-02-10 标题:Long decay phosphors 发明人:BERNER DETLEF; GÜDEL HANS U; RIGOT ISABELLE; GIROD ROMAIN; KENZELMANN CHRISTOPH 权利人:ROLEX SA 摘要:The present invention relates to long decay phosphors comprising rare earth activated strontium aluminates and methods for producing them. The phosphors comprise a matrix of the formula Sr 4 Al 14 O 25 comprising europium as an activator and a further rare earth element as a co-activator, wherein the molar ratio of Al/Sr in the starting materials is in the range of 3.1 to less than 3.5 and the ratio of Eu/Sr is in the range of 0.0015 to 0.01. The process for the preparation of a phosphor comprises the steps of milling the starting materials for the synthesis of the phosphor, the starting materials comprising a boron compound selected from boric acid, boric oxide or a borate salt in an amount such that the B/Sr molar ratio is between 0.1 and to 0.3, treating the milled composition with heat, grinding the block material which is obtained through the heat treatment, ball-milling the crushed material, sieving the material, and washing the material with an aqueous solution.
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合成参考文献
摘要:Acute Toxicity Data. Journal of the American College of Toxicology, Part B., 12(618), 1993