CAS: 405-39-0; Z-Lys(Z)-Oh

相似化合物

55592-85-3 69677-02-7 10009-20-8

上下游产品

Nε-Cbz-lysine L-lysine benzyl chloroformate chloromethyl benzoateNα-(N2,N6-bis-benzyloxycarbonyl-L-lysyl)-Nω-nitro-L-arginine methyl esterNα-(N2,N6-bis-benzyloxycarbonyl-L-lysyl)-Nω-nitro-L-arginine methyl ester Z-Lys(Z)-Gly-OMe N-(N2,N6-bis-benzyloxycarbonyl-L-lysyl)-L-valineN-(N2,N6-bis-benzyloxycarbonyl-L-lysyl)-L-valine 6-[N2',N6'-di(benzyloxycarbonyl)-L-lysyl]-L-lysineN6-[N2',N6'-di(benzyloxycarbonyl)-L-lysyl]-L-lysine

Cbz-Lys(Cbz)-Ome置于氢氧化钾,丙酮体系中,化学反应生成 N,N'-双苄氧羰基-L-赖氨酸
参考文献:Bergmann Et Al.,Hoppe-Seyler'S Zeitschrift Fur Physiologische Chemie,1934,Vol. 224,P. 33,35
标题:Bergmann Et Al.,Hoppe-Seyler'S Zeitschrift Fur Physiologische Chemie,1934,Vol. 224,P. 33,35

专利信息

专利号:US-6166217-A
优先权日:1998-02-09
标题 :Process for the production of alkoxycarbonyldipeptides intermediates in the synthesis of the lisinopril
发明人：CANNATA VINCENZO; MERLI VALERIANO; SAGUATTI STEFANO
权利人:ALLIED SIGNAL INC
摘要:Process for the production of alkoxycarbonyldipeptides intermediates in the synthesis of the lisinopril which comprises protecting both amino functions of the L-lysine with an alkoxycarbonyl group, subsequently making the N-carboxyanhydride of the N6-[alkoxycarbonyl]-L-lysine by treatment with thionyl chloride and making the desired alkoxycarbonyldipeptide by reaction with L-proline in alkaline medium.

专利号:US-8217142-B2
优先权日:1996-07-17
标题 :Liquid phase peptide synthesis of KL-4 pulmonary surfactant
发明人：ABDEL-MAGID AHMED F; EGGMANN URS; MARYANOFF CYNTHIA ANNE; THALER ADRIAN; VILLANI FRANK J
权利人:ABDEL-MAGID AHMED F; EGGMANN URS; MARYANOFF CYNTHIA ANNE; THALER ADRIAN; VILLANI FRANK J; ORTHO PHARMA CORP
摘要:The invention relates to improved liquid phase processes for the preparation of the 21 residue protein component, (Lys-Leu 4 ) 4 -Lys, of the pulmonary surfactant KL-4. These process are amenable to large scale synthesis and one process employs a method of saponifying an ester which reduces the inherent racemization of the α-carbon.

专利号:US-6031112-A
优先权日:1998-02-09
标 题 :Process for the production of alkoxycarbonyl-dipeptides intermediates in the synthesis of the lisinopril

专利号:WO-0110851-A1
优先权日:1999-08-09
标题:Process for the preparation of lysine-carboxyanhydride intermediates in the synthesis of lisinopril

专利号:US-6013764-A
优先权日:1996-07-17
标 题:Liquid phase peptide synthesis of KL-4 pulmonary surfactant

专利号:EP-0943621-A2
优先权日:1998-02-09
标题 :Process for the production of alkoxycarbonylpeptides intermediates in the synthesis of the lisinopril