专利号:US-8669356-B2 优先权日:2009-10-21 标 题 :Linker and support for solid phase synthesis of nucleic acid 发明人:HAYAKAWA YOSHIHIRO; TSUKAMOTO MASAKI; MORI KENJIRO; MINOMI KENJIRO; MAETA ERI; KONISHI TATSUYA 权利人:HAYAKAWA YOSHIHIRO; TSUKAMOTO MASAKI; MORI KENJIRO; MINOMI KENJIRO; MAETA ERI; KONISHI TATSUYA; NITTO DENKO CORP; UNIV NAGOYA NAT UNIV CORP 摘要:The invention provides a universal linker capable of synthesizing nucleic acid having a phosphate group at the 3′ terminal, a universal support carrying the linker, and a synthesis method of nucleic acid using the universal support. The linker for solid phase synthesis of nucleic acid contains a compound represented by at least one of the following formulae n nwherein each symbol is as defined in the specification.
专利号:US-7429658-B2 优先权日:2003-09-11 标题 :Synthesis of protected pyrrolobenzodiazepines 发明人:HOWARD PHILIP; MASTERSON LUKE 权利人:SPIROGEN LTD 摘要:A method of synthesis of a N-10 protected PBD compound of formula (I): n nvia an intermediate of formula (II) or formula (V):
专利号:US-2012029226-A1 优先权日:2009-02-06 标题:Method for the synthesis of chiral alpha-aryl propionic acid derivatives 发明人:KAPTEIN BERNARDUS; VLIEG ELIAS; NOORDUIN WILLEM LIEUWE 权利人:KAPTEIN BERNARDUS; VLIEG ELIAS; NOORDUIN WILLEM LIEUWE 摘要:The present invention provides a method for the synthesis of optically pure α-aryl propionic acid derivatives comprising subjecting the corresponding racemic α-aryl propionic acid derivatives to high sheer or impact forces, such as grinding.
专利号:US-10745354-B2 优先权日:2017-11-01 标题 :Methods for enantioselective allylic alkylation of esters, lactones, and lactams with unactivated allylic alcohols 发明人:STOLTZ BRIAN M; NGAMNITHIPORN AURAPAT; JETTE CARINA I; BACHMAN SHOSHANA; VIRGIL SCOTT C; LACKNER SEBASTIAN 权利人:CALIFORNIA INST OF TECHN 摘要:The present disclosure provides methods for enantioselective synthesis of cyclic and acyclic α-quaternary carboxylic acid derivatives via nickel-catalyzed allylic alkylation.
专利号:US-6066780-A 优先权日:1991-04-26 标题 :Modification of lignin synthesis in plants 发明人:BOUDET ALAIN MICHEL; INZE DIRK GUSTAAF; SCHUCH WOLFGANG WALTER 权利人:ZENECA LTD 摘要:The synthesis of lignin by plants is controlled by transformation of the plant genome with a recombinant gene construct which contains the gene specifying an enzyme critical to the synthesis of a lignin precursor, which gene may be in antisense orientation so that it is transcribed to mRNA having a sequence complementary to the equivalent mRNA transcribed from the endogenous gene thus leading to suppression of lignin synthesis. If the recombinant gene has the lignin enzyme gene in normal, or 'sense' orientation, increased production of the enzyme may occur when the insert is the full length DNA but suppression may occur it only a partial sequence is employed.
专利号:US-7592392-B2 优先权日:2003-04-04 标 题 :Synthesis of functional polymers for use in organic synthesis and combinatorial chemistry 发明人:LINDSLEY CRAIG W; WISNOSKI DAVID D 权利人:MERCK & CO INC 摘要:The present invention relates to a novel process for the preparation of solid-supported scavenging reagents and solid-supported functional polymers. The invention further relates to novel solid-supported functional polymers and to their use in organic synthesis and combinatorial chemistry.
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合成参考文献
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