CAS: 2232-12-4; 1,3-Diiodo-5,5-Dimethylimidazolidine-2,4-Dione

相似化合物

77-48-5 118-52-5 16079-88-2

上下游产品

CAS号77-71-4 5,5-二甲基海因 | CAS号7553-56-2 碘

5,5-二甲基海因置于sodium Hydroxide,一氯化碘体系中,用 氯仿 用作溶剂,化学反应 0.25H,以48%的收率获得1,3-二碘-5,5-二甲基海因
参考文献:Carbon-14 Labeling Of A Trifluoromethoxy Group: Synthesis Of A Substance P Antagonist
标题:Carbon-14 Labeling Of A Trifluoromethoxy Group: Synthesis Of A Substance P Antagonist
摘要:通过对容易制备的[14C]黄原酸盐(5)进行逐步氧化氟化-脱硫,合成了碳-14 标记的三氟甲氧基.这种新颖的标记程序可以快速合成候选的 P 物质拮抗剂 1,避免了可能更为复杂的环标记程序.类似的程序也被用于制备 C-14 标记的三氟甲基和三氟甲胺基团.Copyright © 2001 John Wiley & Sons,Ltd. All Rights Reserved.
Doi:10.1002/jlcr.502

专利信息

专利号:US-2024174698-A1
优先权日:2022-09-23
标题 :Modular synthesis of 1,2-azaborines via ring-opening bn-isostere benzannulation
发明人：DONG GUANGBIN; LYU HAIRONG; CHEN ZHIJIE; WU YIFEI; CHOI SHINYOUNG
权利人:UNIV CHICAGO
摘要:The present disclosure relates generally to 1,2-azaborines and methods of making the same.

专利号:US-2009198084-A1
优先权日:2006-05-02
标题:Process for the deprotection of protected amines
发明人：ALSTERS PAULUS LAMBERTUS; VERKADE JORGE MERIJN MATHIEU; QUAEDFLIEG PETER JAN LEONARD MARIO; RUTJES FLORIS PETRUS JOHANNES
权利人:ALSTERS PAULUS LAMBERTUS; VERKADE JORGE MERIJN MATHIEU; QUAEDFLIEG PETER JAN LEONARD MARIO; RUTJES FLORIS PETRUS JOHANNES
摘要:The present invention relates to a process for the deprotection of protected amine compounds, wherein the protected amine compound is contacted with an electrophilic oxidating agent that is optionally formed in situ, said electrophilic oxidating agent being selected from the group of I 2 , Br 2 , Cl 2 and compounds comprising a halogen atom having a formal oxidation state of 1+, 3+, 5+ or 7+, provided that the electrophilic oxidating agent is not iodobenzene diacetate. The process can be conveniently employed in the synthesis of 1,3-amino alcohols, β-amino acids and heterocyclic compounds, in particular β-amino acids.

专利号:US-10081610-B2
优先权日:2014-09-12
标题 :Efficient and scalable synthesis of 2-(1′h-indole-3′-carbonyl)-thiazole-4-carboxylic acid methyl ester and its structural analogs
发明人：SONG JIASHENG; ZHANG SUOMING; LI GUODONG; YANG LUQUING
权利人:ARIAGEN INC
摘要:Methods of synthesizing 2-(1′H-indole-3′-carbonyl)-thiazole-4-carboxylic acid methyl ester (ITE) and structural analogs thereof. The methods include condensation reactions or condensation and oxidation reactions to form the thiazoline or thiazole moiety of ITE or its structural analogs.

专利号:US-12172982-B2
优先权日:2020-08-12
标 题:Synthesis of quinazoline compounds
发明人：LIM NGIAP-KIE; SHEN JEFF; SIROIS LAUREN ELIZABETH; TIMMERMAN JACOB C; TRACHSEL ETIENNE; WHITE NICHOLAS ANDREW; XU JIE; ZHANG HAIMING; BACHMANN STEPHAN; BIGLER RAPHAEL; CLAGG KYLE BRADLEY PASCUAL; DIPASQUALE ANTONIO GIOVANNI; GOSSELIN FRANCIS; ORCEL UGO JONATHAN; MEIER ROLAND CHRISTOPH
权利人:GENENTECH INC; HOFFMANN LA ROCHE
摘要:Provided herein are methods of synthesizing quinazoline compounds comprising at least one atropisomeric center.

专利号:US-10611739-B2
优先权日:2016-08-16
标题:Process for preparation of lactone derivatives and intermediates thereof
发明人：CHEN PING; PENG SHAOPING; LI YINQIANG; LI DAFENG; DONG XUEJUN
权利人:PHARMARESOURCES SHANGHAI CO LTD
摘要:A novel process for the preparation of lactone derivatives, and intermediates thereof is described. The lactone derivatives are important precursors for the synthesis of anti-hepatitis C virus agents, including sofosbuvir.

专利号:CN-118891266-A
优先权日:2022-03-18
标题:Decarboxylation acetoxylation using Mn (II) or Mn (III) reagent for synthesis of 4 '-acetoxy-nucleoside and use thereof for synthesis of corresponding 4' - (dimethoxyphosphoryl) methoxy-nucleotide