CAS: 4549-33-1; 1,9-Dibromononane

该化合物是一种有机化合物,其特征是存在一个非烷脊椎,与第一个和第九个碳原子相连的两个溴原子,该化合物属于烷基卤化物类,特别是二溴化物,在室温下一般是无色的黄色液体,其分子式为C9H18BR2,表明含有9个碳原子,18个氢原子和两个溴原子.溴原子的存在对其物理和化学特性有重大影响,包括密度和潜在再活性增加.1,9-二溴诺烷在有机溶剂中溶解,但因其缺水性非烷结构,在水中溶解性有限.它可以参与各种化学反应,如核分裂替代和清除反应,使其在有机合成中有用.此外,在处理该化合物时,应采取安全防范措施,因为溴化化合物可能有害,并可能对环境造成危害.

结构式图片

相似化合物

3344-70-5 4101-68-2 4549-31-9

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

1,9-dimethoxynonane 1,9-Nonanediol Dimethyl azelate 2-(9-bromononyloxy)tetrahydropyran 1,9-dimorpholino-nonane brassylic acid 1,9-bis-(4-nitro-phenoxy)-nonane N-(9-bromo-nonyl)-toluene-4-sulfonamideN-(9-bromo-nonyl)-toluene-4-sulfonamide

合成工艺路线路线简述

    壬二酸置于异戊醇,硫酸,氢溴酸,Sodium体系中,化学反应生成 1,9-二溴壬烷
    参考文献:Chuit,Helvetica Chimica Acta,1926,Vol. 9,P. 265
    标题:Chuit,Helvetica Chimica Acta,1926,Vol. 9,P. 265

    海关参考信息

    专利信息


    专利号:US-7557099-B2
    优先权日:2004-03-01
    标题 :Pyrrolobenzodiazepines as key intermediates in the synthesis of dimeric cytotoxic pyrrolobenzodiazepines
    发明人:HOWARD PHILIP WILSON; KANG GYOUNG-DONG
    权利人:SPIROGEN LTD
    摘要:Compounds and a method of synthesis of compounds of formula (Ia) or (Ib): and salts, solvates, and chemically protected forms thereof, wherein the dotted lines indicate the optional presence of a double bond between C1 and C2 or C2 and C3; R 2 and R 3 are independently selected from —H, â•?O, â•?CH 2 , —CN, —R, OR, halo, â•?CH—R, O—SO 2 —R, CO 2 R and COR; R 10 is a carbamate-based nitrogen protecting group; and R 11 is an oxygen protecting group.

    专利号:US-2009111737-A1
    优先权日:1999-05-24
    标题:Novel antibacterial agents
    发明人:CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
    权利人:CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
    摘要:This invention relates to novel multibinding compounds (agents) that are antibacterial agents. The multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands in their monovalent (i.e., unlinked) state have the ability to bind to a an enzyme involved in cell wall biosynthesis and metabolism, a precursor used in the synthesis of the bacterial cell wall and/or the bacterial cell surface thereby interfere with the synthesis and/or metabolism of the cell wall. In particular the multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands hasn a ligand domain capable of binding to penicillin binding proteins, a transpeptidase enzyme, a substrate of a transpeptidase enzyme, a beta-lactamase enzyme, pencillinase enzyme, cephalosporinase enzyme, a transglycoslase enzyme, or a transglycosylase enzyme substrate; Preferably, the ligands are selected from the beta lactam or glycopeptide class of antibacterial agents.

    专利号:US-8968421-B2
    优先权日:2011-10-14
    标题:Synthesis and application reactive antimicrobial copolymers for textile fibers
    发明人:LOCKLIN JASON J
    权利人:UNIV GEORGIA; UNIV GEORGIA
    摘要:Polymer compositions, methods of making polymer compositions, structures (e.g., textile articles) having the polymer composition covalently bonded to the structure, methods of attaching the polymer to the surface of the structure having —OH functionality (e.g., C alkyl —OH), methods of decreasing the amount of microorganisms formed on a structure, and the like, are provided herein.

    专利号:US-9006467-B2
    优先权日:2011-02-14
    标题:1,2,3-triazole containing artemisinin compounds and process for preparation thereof
    发明人:SAIKIA BISHWAJIT; BARUA NABIN C; SAIKIA PARTHA P; GOSWAMI ABHISHEK; RAO PARUCHURI G; SAXENA AJIT K; SURI NITASHA
    权利人:SAIKIA BISHWAJIT; BARUA NABIN C; SAIKIA PARTHA P; GOSWAMI ABHISHEK; RAO PARUCHURI G; SAXENA AJIT K; SURI NITASHA; COUNCEL OF SCIENT & IND RES
    摘要:The present invention relates to 1,2,3-triazole containing artemisinin compounds and process for preparation thereof. Described herein is the synthesis, bioassay results and usefulness of the artemisinin derived compounds resulting from 1,3-dipolar cycloaddition reaction of artemisinin derived azide or alkyne with aliphatic or aromatic diazides. These 1,2,3-triazole containing artemisinin derived compounds embodied in this document are found to be active against various cancer cell-lines.

    专利号:US-8876914-B2
    优先权日:2010-04-26
    标 题:Synthesis and application reactive antimicrobial copolymers for textile fibers
    发明人:LOCKLIN JASON J
    权利人:LOCKLIN JASON J; UNIV GEORGIA
    摘要:Embodiments of the present disclosure provide polymer compositions, methods of making polymer compositions, structures (e.g., textile articles) having the polymer composition covalently bonded to the structure, methods of attaching the polymer to the surface of the structure, methods of decreasing the amount of microorganisms formed on a structure, and the like.

    专利号:US-2007191309-A1
    优先权日:2004-03-01
    标题 :Pyrrolobenzodiazepines as key intermediates in the synthesis of dimeric cytotoxic pyrrolobenzodiazepines
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    主要参考文献

    参考标题:Synthesis Of Bivalent Organophosphorus Compounds As Acetylcholinesterase Inhibitors
    作者:Guoquan Yang,Qianfei Zhao,Yonghong Li,Huizhu Yuan,Xiangdong Mei,Jun Ning |发布日期:2008.10
    摘要:Glu199, Asp-276 And The Hydrophobic Residues Lining The Entrance Gorge Of Ache Through Binding To Both Catalytic And Peripheral Sites Of The Enzyme, A New Series Of Dual Binding Site Ache Inhibitors Have Been Designed And Synthesized.1° The Cluster Effect, Combined With Information About The Structure Of Acetylcholinesterase, Led Us To Design And Synthesize Some Bivalent Organphosphorus Compounds As

    合成参考文献


    摘要:Shinmyozu, T.; Shibahara, M., Science of Synthesis, (2010) 45, 1272.
    摘要:Shinmyozu, T.; Shibahara, M., Science of Synthesis, (2010) 45, 1282.
    摘要:Joule, J. A., Science of Synthesis Knowledge Updates, (2018) 2, 302.
    摘要:Park, K.; Jo, H., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 1, 915.
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