CAS: 50607-30-2; Piperidine-2,4-Dione

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CAS号845267-78-9 2,4-二哌啶酮-1-甲酸叔丁酯 | CAS号476014-76-3 4-羟基-2-哌啶酮 | CAS号1026386-87-7 ethyl 2,4-dioxo... | CAS号476014-76-3 4-羟基-2-哌啶酮 | CAS号845714-00-3 1,5,6,7-四氢-2-(4...

3-((3-乙氧基-3-氧代丙基)氨基)-3-氧代丙酸乙酯置于水,Sodium体系中,用 乙醇,乙腈 作为反应溶剂,化学反应 10.0H,反应生成 2,4-哌啶二酮
参考文献:Furo-3-Carboxamide Derivatives And Methods Of Use
标题:Furo-3-Carboxamide Derivatives And Methods Of Use
摘要:式(I)化合物的药物可接受的盐,酯,酰胺或放射性标记形式,其中r1,Z1,Z2和n如说明书中所定义,可用于治疗通过或通过原肌球蛋白受体激酶(Trk)预防或缓解的病症或障碍.制备这些化合物的方法已被公开.还公开了式(I)化合物的药物组合物,以及使用这些化合物和组合物的方法.

专利信息

专利号:US-6686503-B2
优先权日:1999-04-14
标 题 :Methods for the synthesis of highly substituted 2,4-dioxopiperidine libraries
发明人：CHAI WENYING; MURRAY WILLIAM V
权利人:ORTHO MCNEIL PHARM INC
摘要:The invention relates to methods of synthesizing libraries of diverse and complex highly substituted 2,4-dioxopiperidine compounds of the general formula:wherein R<1>, R<2 >and R<3 >are as herein described, novel intermediates useful for synthesizing such 2,4-dioxopiperidine compounds and methods for identifying and isolating the compounds.

专利号:WO-2023086799-A1
优先权日:2021-11-09
标 题:Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists
发明人：HOUZE JONATHAN B; PANDYA BHAUMIK; KAPLAN ALAN P
权利人:VIGIL NEUROSCIENCE INC
摘要:The present disclosure provides compounds of Formula I, useful for the activation of Triggering Receptor Expressed on Myeloid Cells 2 ('TREM2'). This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a neurodegenerative disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula I.

专利号:US-6288235-B1
优先权日:1999-04-14
标 题 :Methods for the synthesis of highly substituted 2,4-dioxopiperidine libraries

专利号:US-2001041345-A1
优先权日:1999-04-14
标 题:Methods for the synthesis of highly substituted 2,4-dioxopiperidine libraries

专利号:US-4645838-A
优先权日:1982-05-12
标题 :Pyrazolopyridine compounds, and intermediates, useful as anxiolytic agents
发明人：BARE THOMAS M; HEALD ANTHONY F
权利人:ICI AMERICA INC
摘要:Compounds of the formula (I): ##STR1## wherein R 1 , R 3 , R 4 , R 7 and R 8 are as described herein, D is oxygen, n is 1 or 2 and the physiologically acceptable salts thereof useful in reducing anxiety in an animal such as man. The compounds are potent anxiolytics having reduced side effects compared to known anxiolytics. Also pharmaceutical compositions, intermediates and methods of treatment and synthesis are described.