CAS: 57260-71-6; Tert-Butyl Piperazine-1-Carboxylate

相似化合物

76535-74-5 57260-72-7 109-01-3

上下游产品

CAS号110-85-0 哌嗪 | CAS号24424-99-5 二碳酸二叔丁酯 | CAS号164331-38-8 4-(甲基磺酰基)哌嗪-1-羧酸叔丁酯 | CAS号219509-79-2 4-甲基哌嗪-1,4-二羧酸-1-叔丁酯 | CAS号57260-70-5 1-苄基-4-B°C-哌嗪 | CAS号121370-60-3 1-苄基 4-叔丁基 哌嗪-1... | CAS号1076-22-8 3-甲基黄嘌呤 | CAS号3355-28-0 1-溴-2-丁炔 | CAS号85-18-7 8-氯茶碱 | CAS号1072027-36-1 4-(4-B°C-1-哌嗪基)... | CAS号327030-39-7 4-(3-溴苯基)哌嗪-1-羧酸叔丁酯 | CAS号38212-33-8 1-(4-氯苯基)哌嗪 | CAS号497915-42-1 4-(5-碘-2-吡啶基)胡椒... | CAS号40172-95-0 1-(2-糠酰)哌嗪 | CAS号374930-88-8 5-溴-2-(4-b°C-哌嗪... | CAS号39512-50-0 1-(2-氯苯基)哌嗪 | CAS号492431-11-5 1-B°C-4-(6-氯-哒嗪... | CAS号509073-62-5 4-(4-硝基苯甲酰基)哌嗪-... | CAS号494773-35-2 4-(2-溴苯基)哌嗪-1-羧酸叔丁酯

N,N-双(2-氯乙基)氨基甲酸叔丁酯置于ammonium Hydroxide体系中,化学反应 5.5H,以94.3%的收率获得产物n-Boc-哌嗪
参考文献:一种n-Boc哌嗪的合成方法
标题:一种n-Boc哌嗪的合成方法
摘要:本发明公开了一种n‑boc哌嗪的合成方法.该方法以二乙胺醇为起始物料,经过氯化,Boc保护,氨解环合三步合成n‑boc哌嗪.该方法的原料易得,反应条件温和,产品的成本低,收率高,纯度高,适宜于工业化生产.

专利信息

专利号:US-2024092821-A1
优先权日:2020-03-31
标题:Synthesis of oligonucleotides and related compounds
发明人：ZHONG MINGHONG; JIN YI; GALA DINESH; PRHAVC MARIJA
权利人:JANSSEN BIOPHARMA INC
摘要:Methods of synthesizing oligonucleotides via new intermediates on a cleavable support having an azidomethyl moiety are disclosed. The method comprises multiple reaction cycles, each of which comprises sequential coupling a nucleoside or oligonucleotide subunit on a cleavable support having an azidomethyl moiety and a nucleoside phosphoramidite or an oligonucleotide phosphoramidite, capping, oxidation/thiolation and deblocking; followed by orthogonal cleavage of the azidomethyl support while keeping all other protecting groups intact. The method can be used in combination with a support moiety for either solid phase or liquid phase oligo synthesis. The soluble support facilitates homogeneous reactions and efficient separations by simple precipitation. The methods also provide novel intermediates useful in the synthesis of oligonucleotide conjugates.

专利号:WO-2005051933-A1
优先权日:2003-11-28
标题 :An improved process for the synthesis of 4-(4-benzyloxy-carbonylamino-2-fluorophenyl)-piperazine-1-carboxylic acid tert-butyl ester, a key intermediate for oxazolidinone antimicrobials and compounds prepared thereby
发明人：KUMAR YATENDRA; KAUL VIJAY KUMAR; SINGH NITU; YADAV GYAN CHAND
权利人:RANBAXY LAB LTD; KUMAR YATENDRA; KAUL VIJAY KUMAR; SINGH NITU; YADAV GYAN CHAND
摘要:Provided herein are process for the synthesis of the 4-(4-benzyloxy-carbonylamino-2-fluorophenyl)-piperazine-1-carboxylic acid tert-butyl ester, which is a key intermediate in the synthesis of oxazolidinone compounds having antibacterial activity. Also provided herein are processes for preparing oxazolidinone compounds. In addition, compounds prepared by the processes provided herein are also encompassed. Formula (I) and Formula (II).

专利号:US-2025179012-A1
优先权日:2022-03-04
标 题:Synthesis of sulfur(vi) compounds and reagents for same
发明人：LOPCHUK JUSTIN MATTHEW; SHULTZ ZACHARY
权利人:H LEE MOFFITT CANCER CT & RES
摘要:This disclosure provides reagents and processes for the synthesis of organic compounds, more particularly reagents and processes for the asymmetric synthesis of sulfur (VI) containing organic compounds.

专利号:US-9688644-B2
优先权日:2009-04-30
标 题 :Synthesis of Tetracyclines and intermediates thereto
发明人：MYERS ANDREW G; KUMMER DAVID A; LI DERUN; HECKER EVAN; DION AMELIE; WRIGHT PETER M
权利人:HARVARD COLLEGE
摘要:The tetracycline class of antibiotics has played a major role in the treatment of infectious diseases for the past 50 years. However, the increased use of the tetracyclines in human and veterinary medicine has led to resistance among many organisms previously susceptible to tetracycline antibiotics. The recent development of a modular synthesis of tetracycline analogs through a chiral enone intermediate has allowed for the efficient synthesis of novel tetracycline analogs never prepared before. The present invention provides more efficient routes for preparing the enone intermediate and allows for substituents at positions 4a, 5, 5a, and 12a of the tetracycline ring system.

专利号:US-2025250302-A1
优先权日:2024-02-05
标题:Synthesis of self-assembling artificial proteins utilizing a host-guest system and uses thereof
发明人：SANDANARAJ BRITTO S; KHYADE ASHWINI RAJENDRA; HATI KSHITISH CHANDRA
权利人:INDIAN INSTITUTE OF SCIENCE EDUCATION AND RES PUNE IISER PUNE
摘要:The invention relates to an efficient method for synthesizing self-assembling artificial proteins (SAPs) utilizing a catalytic host-guest system. The process involves encapsulating hydrophobic probes with cyclodextrin, performing site-specific protein bioconjugation, and employing a second catalysis cycle for enhanced labeling. SAPs produced through this method are versatile and find applications in therapeutic delivery and diagnostics. The process is simplified, scalable, cost-effective, and environmentally sustainable, addressing the challenges of traditional SAP synthesis. By offering improved yield, functionality, and structural integrity, this invention advances the potential of SAPs in medical and industrial fields.

专利号:WO-2025101716-A1
优先权日:2023-11-07
标题:Processes for synthesis of trifunctionalized sulfur(vi) compounds
发明人：LOPCHUK JUSTIN; SHULTZ ZACHARY; ATHAWALE PARESH
权利人:H LEE MOFFITT CANCER CT & RES
摘要:This disclosure describes processes for the asymmetric synthesis of trifunctionalized sulfur(VI) containing organic compounds of Formula I and Formula VI, as well as compounds of Formula I and Formula VI prepared by the processes described.