专利号:US-9029547-B1 优先权日:2013-12-07 标 题 :Synthesis of 4-aryl 4-acyl piperidine, its salts and analogs using indium metal 发明人:MAJEED MUHAMMED; RAMANUJAM RAJENDRAN; NAGABHUSHANAM KALYANAM 权利人:MAJEED MUHAMMED; RAMANUJAM RAJENDRAN; NAGABHUSHANAM KALYANAM 摘要:A novel process for the synthesis of 4-aryl 4-acyl piperidine derivatives using indium metal is described. Specifically, a novel process for the synthesis of 4-acetyl 4-phenyl piperidine and its salts using indium metal is described. This divisional application is specifically drawn to compounds 4-aryl 1,4-diacyl piperidine and 1,4 diacetyl 4-phenyl piperidine.
专利号:US-6399536-B2 优先权日:2000-02-11 标 题 :High performance catalyst systems for the synthesis of alkylenecarbonates 发明人:KIM HOON SIK; LEE BYUNG GWON; LEE SANG DEUK; KWON YOUNG SOO; LEE HYUN JOO 权利人:KOREA INST SCI & TECH 摘要:A catalyst of the formula (1) for the synthesis of alkylene carbonate by reacting alkylene oxide and carbon dioxide n n n L m MX n   (1) n n n wherein L is selected from a group of pyridines; n M is a metal atom selected from Zn, Fe, Mn, Pb and In; n X is a halogen atom selected from Cl, Br and I; n m is 1 or 2, and n n is 2 or 3.
专利号:US-8735586-B2 优先权日:2007-06-26 标 题 :Regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles 发明人:ALONSO JORGE; LINDENSCHMIDT ANDREAS; NAZARÉ MARC; URMANN MATTHIAS; HALLAND NIS; RKYEK OMAR 权利人:ALONSO JORGE; LINDENSCHMIDT ANDREAS; NAZARÉ MARC; URMANN MATTHIAS; HALLAND NIS; RKYEK OMAR; SANOFI SA 摘要:The present invention relates to a process for the regioselective synthesis of compounds of the formula I, n nwherein R0; R1; R2; R3; R4; R5; A1; A2; A3; A4, Q and J have the meanings indicated in the claims. The present invention provides a direct copper catalyzed regioselective process to a wide variety of unsymmetrical, multifunctional N-substituted benzimidazoles or azabenzimidazoles of formula I starting from 2-halo-nitroarenes and N-substituted amides.
专利号:US-8110642-B2 优先权日:2006-05-08 标 题:Synthesis of vinylphenylpyridine and living anionic polymerization 发明人:LEE JAE-SUK; KANG NAM-GOO 权利人:LEE JAE-SUK; KANG NAM-GOO; KWANGJU INST SCI & TECH 摘要:Provided are a vinyl-biphenylpyridine monomer and a polymer thereof. More particularly, the present invention provides a vinyl-biphenylpyridine monomer having a side chain of pyridine or phenylpyridine as a functional group, a homopolymer of which molecular weight and molecular weight distribution are controlled using the monomer, and a block copolymer of which molecular structure and molecular weight are controlled to facilitate synthesis of an organic metal complex. Accordingly, the present invention provides a vinyl-biphenylpyridine monomer and a polymer thereof which are effectively used as nano and optical functional materials.
专利号:US-12331021-B2 优先权日:2020-09-10 标题 :Total synthesis of pirfenidone 发明人:ZHOU LIHUA 权利人:SUZHOU FUDE ZHAOFENG BIOCHEMICAL TECH CO LTD 摘要:The present invention relates to a process for the synthesis of Pirfenidone (1) from 5-Methyl-3,4-dihydro-2-pyridone and halobenzene (chlorobenzene, bromobenzene, or iodobenzene) in the presence of a catalytic system consisting of a copper salt and an organic ligand, in the presence of a base.
专利号:US-6492524-B1 优先权日:2001-03-27 标 题 :Process for the synthesis of an aryl pyridine base using a zeolite catalyst 发明人:KULKARNI SHIVANAND JANARDAN; RAGHAVAN KONDAPURAM VIJAYA; NAGABANDI SRINIVAS; VIPPAGUNTA RADHA RANI 权利人:COUNCIL SCIENT IND RES 摘要:The present invention provides an improved process for the synthesis of aryl pyridine bases by reacting an aromatic aldehyde or ketone and allylic alcohol or aldehyde in presence of ammonia in gas phase, in high yield and selectivity with catalyst obtained by optionally modifying a zeolite having an atomic ratio of Si to Al, 2.5 to 12.5 and /or with at least one metal ion and/or metal compound selected from the group consisting of lead and lanthanum. This process provides an eco-friendly, more economical and highly selective heterogeneous method.
参考文献:10.1021/np200258h 摘要:Fu P, Wang S, Hong K, Li X, Liu P, Wang Y, Zhu W. Cytotoxic bipyridines from the marine-derived actinomycete Actinoalloteichus cyanogriseus WH1-2216-6. J Nat Prod. 2011 Aug 26;74(8):1751–6. doi: 10.1021/np200258h.