CAS: 26054-60-4; (S)-Benzyl (2-Oxooxetan-3-yl)Carbamate

上下游产品

CAS号1145-80-8 |N|-苄氧羰基-L-丝氨酸 | CAS号81187-75-9 Z-Ser-OMpt | CAS号42918-86-5 (S)-2-(苄氧羰基氨基)丁酸 | CAS号35761-26-3 |N|{α}-苄氧羰基-L-2... | CAS号185521-30-6 (2R)-3-[methoxy... | CAS号19647-68-8 (S)-(3-羟基-1-(甲基... | CAS号20945-53-3 L-n-cbz-3-吡唑-1-基-丙氨酸 | CAS号78553-51-2 N-cbz--l-烯丙基甘氨酸 | CAS号159878-01-0 (R)-(-)-3-(苄氧羰基... | CAS号70897-15-3 (S)-(1-氨基-3-羟基-... | CAS号82611-65-2 N-CBZ-S-苯基-L-半胱氨酸

Z-Ser-Ompt置于三乙胺体系中,化学反应生成N-苄氧羰基-L-丝氨酸(β-内酯)
参考文献:不保护羟基功能的混合酸酐法合成含羟基氨基酸的肽
标题:不保护羟基功能的混合酸酐法合成含羟基氨基酸的肽
摘要:发现 N 保护氨基酸的二甲基硫代膦酰 (Mpt) 混合酸酐可分离稳定,可用于合成含羟基氨基酸的肽,而无需保护侧链羟基官能团.它们被应用于在 C 端延伸的脑啡肽类似物的固相合成.
Doi:10.1246/cl.1982.45

专利信息

专利号:US-5846993-A
优先权日:1992-12-22
标题:HIV protease inhibitors
发明人：DRESSMAN BRUCE A; FRITZ JAMES E; KALDOR STEPHEN W; KALISH VINCENT J; REICH SIEGFRIED HEINZ; TATLOCK JOHN H; RODRIGUEZ MICHAEL J
权利人:AGOURON PHARMA
摘要:HIV protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds, as well as pharmaceutical compositions that contain these compounds and optionally other anti-viral agents as active ingredients, are suitable for treating patients or hosts infected with the HIV virus, which is known to cause AIDS.

专利号:US-6271235-B1
优先权日:1992-12-22
标题:HIV protease inhibitors
发明人：DRESSMAN BRUCE A; FRITZ JAMES E; KALDOR STEPHEN W; KALISH VINCENT J; REICH SIEGFRIED HEINZ; RODRIGUEZ MICHAEL J; SHEPHERD TIMOTHY A; TATLOCK JOHN H; JUNGHEIM LOUIS NICKOLAUS
权利人:AGOURON PHARMA
摘要:HIV protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds, as well as pharmaceutical compositions that contain these compounds and optionally other anti-viral agents as active ingredients, are suitable for treating patients or hosts infected with the HIV virus, which is known to cause AIDS.

专利号:RU-2175316-C2
优先权日:1995-12-20
标题 :Aryl-s(o)n-substituted carboxylic-hydroxamic acids and method of their synthesis

专利号:US-5527829-A
优先权日:1994-05-23
标 题 :HIV protease inhibitors
发明人：KALISH VINCENT J
权利人:AGOURON PHARMA
摘要:HIV protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds, as well as pharmaceutical compositions that contain these compounds and optionally other anti-viral agents as active ingredients, are suitable for treating patients or hosts infected with the HIV virus, which is known to cause AIDS.