CAS: 491-67-8; 5,6,7-Trihydroxy-2-Phenyl-4H-Chromen-4-One

上下游产品

CAS号973-67-1 5,6,7-三甲氧基黄酮 | CAS号29550-13-8 7-甲醚黄芩素 | CAS号21967-41-9 黄芩苷 | CAS号480-11-5 千层纸素A | CAS号671791-94-9 2',4',5',6'-tet... | CAS号67047-05-6 4-oxo-2-phenyl-... | CAS号28279-72-3 黄芩素 6-O-葡萄糖苷 | CAS号150036-33-2 6,7-dihydroxy-5... | CAS号642-71-7 3,4,5-三甲氧基苯酚 | CAS号412027-80-6 7-hydroxy-5-met... | CAS号480-11-5 千层纸素A | CAS号740-33-0 荠苧黄酮 | CAS号2035-05-4 7-hydroxy-5,6-d... | CAS号29550-13-8 7-甲醚黄芩素 | CAS号973-67-1 5,6,7-三甲氧基黄酮 | CAS号3162-43-4 5,6,7,8-tetrame... | CAS号21967-41-9 黄芩苷 | CAS号73202-52-5 5,8-二羟基-6,7-二甲氧基黄酮

汉黄芩素置于氢碘酸,乙酸酐体系中,化学反应生成 黄芩素
参考文献:Hattori,Chemische Berichte,1939,Vol. 72,P. 1914,1916
标题:Hattori,Chemische Berichte,1939,Vol. 72,P. 1914,1916

专利信息

专利号:WO-2020032913-A1
优先权日:2018-08-04
标题:Process for synthesis of oroxylin a
发明人：MAJEED MUHAMMED; NAGABHUSHANAM KALYANAM; RAMANUJAM RAJENDRAN; HEMANTHA HOSAHALLI
权利人:MAJEED MUHAMMED; NAGABHUSHANAM KALYANAM; RAMANUJAM RAJENDRAN; HEMANTHA HOSAHALLI PRABHAKARA
摘要:Disclosed is a novel, simple, scalable and environment friendly process for the synthesis of Oroxylin A from Baicalin. Baicalm is esterified to obtain a methyl ester which is further selectively methylated to provide Oroxylin A gluciironide methyl ester which on de- glycosylation results in the formation of Oroxylin A.

专利号:WO-2025081225-A1
优先权日:2023-10-17
标 题 :Synthesis of polyphenols
发明人：TURLAND CADE LACHLAN; GROLMAN DAVID; BEHRENDORFF JAMES BRUCE YARNTON HAYCOCK; MORADI SHAYLI VARASTEH; THOMSON RAINE ELIZABETH STURT
权利人:Delica Therapeutics Pty Ltd
摘要:The present disclosure relates to polyphenols, including flavonoids, flavones and cannflavins, and methods of synthesising polyphenols. The present disclosure provides methods, enzymes and compositions that may be useful in the synthesis of polyphenols.

专利号:US-10407401-B1
优先权日:2018-08-04
标题 :Process for synthesis of Oroxylin A
发明人：MAJEED MUHAMMED; NAGABHUSHANAM KALYANAM; RAMANUJAM RAJENDRAN; HEMANTHA HOSAHALLI PRABHAKARA
权利人:MAJEED MUHAMMED; NAGABHUSHANAM KALYANAM; RAMANUJAM RAJENDRAN; HEMANTHA HOSAHALLI PRABHAKARA; SAMI LABS LTD
摘要:Disclosed is a novel, simple, scalable and environment friendly process for the synthesis of Oroxylin A from Baicalin. Baicalin is esterified to obtain a methyl ester which is further selectively methylated to provide Oroxylin A glucuronide methyl ester which on de-glycosylation results in the formation of Oroxylin A.

专利号:WO-2023092547-A1
优先权日:2021-11-29
标题 :Smart cell factory of high value-added metabolite constructed on basis of automation technology
发明人：LUO XIAOZHOU; DENG HUAXIANG; Deng Yanwu; QIU YULAN; SHEN JUNFENG; YU HAN
权利人:SHENZHEN INST OF ADV TECH CAS; SENRIS BIOTECHNOLOGY SHENZHEN CO LTD
摘要:A smart cell factory of a high value-added metabolite constructed on the basis of automation technology, which belongs to the technical field of metabolic engineering. According to the present invention, a key enzyme mutant gene with a high efficiency is screened out from an iterative key enzyme gene mutation library by means of weakening the expression of the key enzyme gene of the high value-added metabolite, using the automation technology, and in combination with a mutation-screening-mutation closed-loop protein evolution method. Further provided are a method for constructing the smart cell factory of the high value-added metabolite and the use thereof. According to the present invention, the problem that there is currently no high-throughput molecular probe for the high value-added metabolite or the molecular probe screening thereof is unstable can be effectively solved, and labor costs are reduced, the protein evolution time is shortened, the inhibitory effects of an intermediate product and a final product are reduced, the core metabolic flux is enhanced, and the efficient synthesis of the high value-added compound is achieved.

专利号:US-2002165207-A1
优先权日:2001-05-02
标题 :Compositions and methods for the treatment of diabetic neuropathy
发明人：ROSENBLOOM RICHARD
摘要:Compositions and a method for the treatment of diabetic neuropathy is disclosed. The compositions comprise a mixture of a compound that promotes synthesis of nerve growth factor, an aldose reductase inhibitor and an antioxidant, optionally formulated in a pharmaceutically acceptable carrier. This combination of active agents provides significant, effective relief of the symptoms of diabetic neuropathy, as well as at least partial recovery of lost neurological function in some cases. In addition, the compositions of the present invention, when used in effective amounts to treat diabetic neuropathy, do not exhibit the severe side effects of many prior art compositions proposed for treatment of this ailment. n In a second aspect, a method for the administration of a composition in accordance with the present invention for the treatment of diabetic neuropathy is disclosed. In the method, an effective amount of the composition of the invention is administered on a regular basis over a period of time sufficient to provide the beneficial effects of relief from the symptoms of diabetic neuropathy, as well as at least some recovery of the damaged nerve tissues.

专利号:US-2024026314-A1
优先权日:2020-11-25
标题 :Polypeptides for use in the synthesis of bioactive phenolic compounds
发明人：ROTHSTEIN STEVEN; AKHTAR TARIQ; CASARETTO JOSE; PERRIN COLBY; VAN GELDER KRISTEN
权利人:ROTHSTEIN STEVEN; AKHTAR TARIQ; CASARETTO JOSE; PERRIN COLBY; VAN GELDER KRISTEN
摘要:Described herein is a polypeptide encoding a prenyltransferase for prenylating a polyphenol and a polypeptide encoding an O-methyltransferase for methylating a polyphenol. For example, the polypeptide comprises or consists of the sequence of SEQ ID NO: 1, 2, 3, 4, 5, and/or 6, and/or a polypeptide listed in Table 1, and/or SEQ ID NO: 7-30, or a variant thereof having at least 80% sequence identity to SEQ ID NO: 1, 2, 3, 4, 5, and/or 6, and/or the polypeptide listed in Table 1, and/or SEQ ID NO: 7-30, or a fragment of the polypeptide or the variant thereof.