CAS: 96-98-0; 4-Methyl-3-Nitrobenzoic Acid

上下游产品

CAS号99-94-5 对甲基苯甲酸 | CAS号104-85-8 对甲苯腈 | CAS号939-79-7 4-甲基-3-硝基氰苯 | CAS号99-87-6 4-异丙基甲苯 | CAS号444667-11-2 4-(羧基甲基)-3-硝基苯甲酸 | CAS号89-58-7 2,5-二甲基硝基苯 | CAS号79822-14-3 4-(4-methyl-3-n... | CAS号4957-14-6 二对甲苯基甲烷 | CAS号106-49-0 对甲苯胺 | CAS号76947-17-6 4,4'-dimethyl-3... | CAS号50820-65-0 吲哚-6-甲酸甲酯 | CAS号55715-03-2 4-溴甲基-3-硝基苯甲酸 | CAS号49592-71-4 4-甲基-3,5-二硝基苯甲酸甲酯 | CAS号31680-07-6 4-甲基-3-硝基苯甲醛 | CAS号350-28-7 3-氟-4-甲基苯甲酸 | CAS号147962-81-0 3-溴-4-甲基苯甲酸乙酯 | CAS号41191-92-8 3-氨基-4-甲基苯甲酸乙酯 | CAS号223519-08-2 3-溴-4-甲基-5-硝基苯甲酸甲酯 | CAS号223519-11-7 3-氨基-5溴-4-甲基苯甲酸甲酯 | CAS号303133-89-3 3-硝基-N-环丙基-4-甲基-苯甲酰胺

对甲苯腈置于硫酸,水,硝酸体系中,化学反应生成 4-甲基-3-硝基苯甲酸
参考文献:Van Scherpenzeel,Recueil Des Travaux Chimiques Des Pays-Bas,1901,Vol. 20,P. 155
标题:Van Scherpenzeel,Recueil Des Travaux Chimiques Des Pays-Bas,1901,Vol. 20,P. 155

专利信息

专利号:US-5369017-A
优先权日:1994-02-04
标题 :Process for solid phase glycopeptide synthesis
发明人：WONG CHI-HUEY; SCHUSTER MATTHIAS
权利人:SCRIPPS RESEARCH INST
摘要:A process for the synthesis of a glycopeptide using a solid phase matrix is disclosed. The matrix is compatible with aqueous and organic solvents and is comprised of a silica-based solid support to which is linked a two-part spacer group having a chain length of about 12 to about 40 methylene groups. The first part of the spacer is covalently bonded to the silica-based support and has a length of about 3 to about 10 methylene groups. The second spacer part is covalently bonded to the first part of the spacer and comprises the distal end of the two part spacer. The second part is soluble as a free molecule in each of water, dimethylformamide and dichloromethane and has a terminal amine or hydroxyl group to which the C-terminal residue of the peptide portion of the glycopeptide chain is bonded. The chain of atoms connecting the desired glycopeptide to the solid phase matrix also includes a moiety having a selectively severable bond which on cleavage of that bond separates the matrix from whatever else is bonded to that moiety.

专利号:US-5968736-A
优先权日:1992-10-01
标 题 :Methods for recording the reaction history of a solid support
发明人：STILL W CLARK; WIGLER MICHAEL H; OHLMEYER MICHAEL H J; DILLARD LAWRENCE W; READER JOHN C
权利人:COLD SPRING HARBOR LAB; UNIV COLUMBIA
摘要:Encoded combinatorial chemistry is provided, where sequential synthetic schemes are recorded using organic molecules, which define choice of reactant, and stage, as the same or different bit of information. Various products can be produced in the multi-stage synthesis, such as oligomers and synthetic non-repetitive organic molecules. Conveniently, nested families of compounds can be employed as identifiers, where number and/or position of a substituent define the choice. Alternatively, detectable functionalities may be employed, such as radioisotopes, fluorescers, halogens, and the like, where presence and ratios of two different groups can be used to define stage or choice. Particularly, pluralities of identifiers may be used to provide a binary or higher code, so as to define a plurality of choices with only a few detachable tags. The particles may be screened for a characteristic of interest, particularly binding affinity, where the products may be detached from the particle or retained on the particle. The reaction history of the particles which are positive for the characteristic can be determined by the release of the tags and analysis to define the reaction history of the particle.

专利号:US-9850345-B2
优先权日:2012-05-24
标题:Polycarbonate polyol compositions and methods
发明人：FARMER JAY J
权利人:SAUDI ARAMCO TECH CO
摘要:In one aspect, the present disclosure encompasses polymerization systems for the copolymerization of CO 2 and epoxides comprising 1) a catalyst including a metal coordination compound having a permanent ligand set and at least one ligand that is a polymerization initiator, and 2) a chain transfer agent having one or more sites capable of initiating copolymerization of epoxides and CO 2 , wherein the chain transfer agent contains one or more masked hydroxyl groups. In a second aspect, the present disclosure encompasses methods for the synthesis of polycarbonate polyols using the inventive polymerization systems. In a third aspect, the present disclosure encompasses polycarbonate polyol compositions characterized in that the polymer chains have a high percentage of —OH end groups, a high percentage of carbonate linkages, and substantially all polycarbonate chains having hydroxyl end groups have no embedded chain transfer agent.

专利号:US-9217012-B2
优先权日:2009-04-08
标题 :Inhibitors of protein tyrosine phosphatases
发明人：ZHANG ZHONG-YIN; ZHANG SHENG
权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP
摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.

专利号:US-6503759-B1
优先权日:1992-10-01
标题 :Complex combinatorial chemical libraries encoded with tags
发明人：STILL W CLARK; OHLMEYER MICHAEL H J; DILLARD LAWRENCE W; READER JOHN C; WIGLER MICHAEL H
权利人:UNIV COLUMBIA; COLD SPRING HARBOR LAB
摘要:Encoded combinatorial chemistry is provided, where sequential synthetic schemes are recorded using organic molecules, which define choice of reactant, and stage, as the same or different bit of information. Various products can be produced in the multi-stage synthesis, such as oligomers and synthetic non-repetitive organic molecules. Conveniently, nested families of compounds can be employed as identifiers, where number and/or position of a substituent define the choice. Alternatively, detectable functionalities may be employed, such as radioisotopes, fluorescers, halogens, and the like, where presence and ratios of two different groups can be used to define stage or choice. Particularly, pluralities of identifiers may be used to provide a binary or higher code, so as to define a plurality of choices with only a few detachable tags. The particles may be screened for a characteristic of interest, particularly binding affinity, where the products may be detached from the particle or retained on the particle. The reaction history of the particles which are positive for the characteristic can be determined by the release of the tags and analysis to define the reaction history of the particle.

专利号:US-5721099-A
优先权日:1992-10-01
标 题 :Complex combinatorial chemical libraries encoded with tags
发明人：STILL W CLARK; WIGLER MICHAEL H; OHLMEYER MICHAEL H J; DILLARD LAWRENCE W; READER JOHN C
权利人:UNIV COLUMBIA; COLD SPRING HARBOR LAB
摘要:Encoded combinatorial chemistry is provided, where sequential synthetic schemes are recorded using organic molecules, which define choice of reactant, and stage, as the same or different bit of information. Various products can be produced in the multi-stage synthesis, such as oligomers and synthetic non-repetitive organic molecules. Conveniently, nested families of compounds can be employed as identifiers, where number and/or position of a substituent define the choice. Alternatively, detectable functionalities may be employed, such as radioisotopes, fluorescers, halogens, and the like, where presence and ratios of two different groups can be used to define stage or choice. Particularly, pluralities of identifiers may be used to provide a binary or higher code, so as to define a plurality of choices with only a few detachable tags. The particles may be screened for a characteristic of interest, particularly binding affinity, where the products may be detached from the particle or retained on the particle. The reaction history of the particles which are positive for the characteristic can be determined by the release of the tags and analysis to define the reaction history of the particle.