CAS: 626-03-9; 4-Hydroxypyridin-2(1H)-One

上下游产品

CAS号18677-43-5 2,4-二甲氧基吡啶 | CAS号626-64-2 4-羟基吡啶 | CAS号5657-64-7 3-氰基-4-羟基-2(1H)-吡啶酮 | CAS号19867-18-6 6-chloro-2-hydr... | CAS号106689-41-2 4-肼基吡啶-2(1H)-酮 | CAS号38767-72-5 4-氨基-2-羟基吡啶 | CAS号58530-53-3 2,4-二溴吡啶 | CAS号2402-91-7 2,3,4-三溴吡啶 | CAS号219735-84-9 2-苄氧基-4-氯-3-硝基-吡啶 | CAS号219735-85-0 4-(2,4-dichloro... | CAS号191090-84-3 4-[(4-chlorophe... | CAS号343781-36-2 2,4-二氯-3-碘吡啶 | CAS号24501-21-1 3-硝基吡啶-2,4-二胺 | CAS号28443-69-8 2,3,5-三氯-4-氨基吡啶

6-氯-1,2-二氢-4-羟基-2-氧代-3-吡啶甲腈置于盐酸,硫酸,锌体系中,化学反应生成 2,4-二羟基吡啶
参考文献:Schroeter Et Al.,Chemische Berichte,1932,Vol. 65,P. 432,441
标题:Schroeter Et Al.,Chemische Berichte,1932,Vol. 65,P. 432,441

专利信息

专利号:EP-0948511-B1
优先权日:1996-12-24
标 题:Chemical synthesis of nucleosides analogs and their incorporation into polynucleotides
发明人：KARPEISKY ALEXANDER; BEIGELMAN LEONID; MATULIC-ADAMIC JASENKA
权利人:SIRNA THERAPEUTICS INC
摘要:Novel nucleosides, process for chemical synthesis of nucleosides and incorporation of the nucleosides into polynucleotides are disclosed. Also described are polynucleotides, such as antisense, TFO and nucleic acid catalysts with one or more modifications, such as 2'-O-amino, L-nucleotides and the others.

专利号:US-4849513-A
优先权日:1983-12-20
标 题 :Deoxyribonucleoside phosphoramidites in which an aliphatic amino group is attached to the sugar ring and their use for the preparation of oligonucleotides containing aliphatic amino groups
发明人：SMITH LLOYD M; FUNG STEVEN; KAISER ROBERT J
权利人:CALIFORNIA INST OF TECHN
摘要:The invention consists of compounds and methods for the synthesis of oligonucleotides which contain one or more free aliphatic amino groups attached to the sugar moieties of the nucleoside subunits. The synthetic method is versatile and general, permitting amino groups to be selectively placed at any position on oligonucleotides of any composition or length which is attainable by current DNA synthetic methods. Fluorescent dyes or other detectable moieties may be covalently attached to the amino groups to yield the corresponding modified oligonucleotide.

专利号:US-5118802-A
优先权日:1983-12-20
标 题:DNA-reporter conjugates linked via the 2' or 5'-primary amino group of the 5'-terminal nucleoside
发明人：SMITH LLOYD M; FUNG STEVEN; KAISER JR ROBERT J
权利人:CALIFORNIA INST OF TECHN
摘要:The invention consists of compounds and methods for the synthesis of oligonucleotides which contain one or more free aliphatic amino groups attached to the sugar moieties of the nucleoside subunits. The synthetic method is versatile and general, permitting amino groups to be selectively placed at any position on oligonucleotides of any composition or length which is attainable by current DNA synthetic methods. Fluorescent dyes or other detectable moieties may be covalently attached to the amino groups to yield the corresponding modified oligonucleotide.

专利号:US-5118800-A
优先权日:1983-12-20
标 题 :Oligonucleotides possessing a primary amino group in the terminal nucleotide
发明人：SMITH LLOYD M; FUNG STEVEN; KAISER JR ROBERT J
权利人:CALIFORNIA INST OF TECHN
摘要:The invention consists of compounds and methods for the synthesis of oligonucleotides which contain one or more free aliphatic amino groups attached to the sugar moieties of the nucleoside subunits. The synthetic method is versatile and general, permitting amino groups to be selectively placed at any position on oligonucleotides of any composition or length which is attainable by current DNA synthetic methods. Fluorescent dyes or other detectable moieties may be covalently attached to the amino groups to yield the corresponding modified oligonucleotide.

专利号:US-4476326-A
优先权日:1983-02-03
标题 :Process for the synthesis of ethanol and acetaldehyde using cobalt compounds with novel promoters
发明人：LIN JIANG-JEN; KNIFTON JOHN F
权利人:TEXACO INC
摘要:Ethanol and/or acetaldehyde are prepared in good yield by contacting methanol, hydrogen and carbon monoxide with a catalyst system comprising a cobalt-containing compound and a promoter in the presence of an inert oxygenated solvent at a temperature of from about 50 DEG C. to about 350 DEG C. and a pressure of at least 500 psig or greater. The combination of cobalt-containing compound and promoter may be (a) a cobalt-containing compound with an organo-sulphur compound, (b) an iodide-containing cobalt compound with a nitrogen-containing compound as promoter, and (c) a cobalt-containing compound with 1,1'-bis(diphenylphosphino)ferrocene.

专利号:EP-0609960-B1
优先权日:1989-09-15
标 题 :New N-heteroarylamide derivatives as inhibitors of acyl coenzyme A: cholestrol acyl transferase
发明人：MCCARTHY PETER A; HAMANAKA ERNEST S; WALKER FREDERICK J; CHANG GEORGE; TRUONG THIEN
权利人:PFIZER
摘要:Compounds of the formula the pharmaceutically acceptable salts thereof, wherein Q and R<1> are as defined below, and novel carboxylic acid and acid halide intermediates used in the synthesis of such compounds. The compounds of formula I are inhibitors of acyl coenzyme A: cholesterol acyltransferase (ACAT) and are useful as hypolipidemic and antiatherosclerosis agents.