CAS: 1575-37-7; 4-Bromobenzene-1,2-Diamine

相似化合物

471239-60-8 875-51-4 5228-61-5

上下游产品

CAS号875-51-4 4-溴-2-硝基苯胺 | CAS号5228-61-5 5-溴-2-硝基苯胺 | CAS号95-54-5 邻苯二胺(OPD) | CAS号36387-84-5 5-溴-2,1,3-苯并恶唑氮氧化物 | CAS号88-74-4 2-硝基苯胺 | CAS号881-50-5 4-溴-2-硝基乙酰苯胺 | CAS号54558-18-8 1,2-二溴-4,5-二硝基苯 | CAS号103-88-8 4'-溴乙酰苯胺 | CAS号106-40-1 对溴苯胺 | CAS号51686-78-3 2,4-二溴硝基苯 | CAS号32046-62-1 5-溴-1H-苯并三氮唑 | CAS号39513-26-3 5-溴-1,3-二氢苯并咪唑-2-酮 | CAS号1753-75-9 5-溴-2,1,3-苯并噻二唑 | CAS号50998-17-9 6-溴喹喔啉 | CAS号4887-88-1 5-溴-1H-苯并咪唑 | CAS号1740-88-1 6-溴-2-氯甲基-1H-苯并咪唑 | CAS号18470-23-0 2,3-二甲基-6-溴喹噁啉 | CAS号95-54-5 邻苯二胺(OPD) | CAS号791595-74-9 5-溴-1H-苯并咪唑-2-胺 | CAS号2379-55-7 2,3-二甲基喹戊啉

2,4-二溴硝基苯置于盐酸,Tin,乙醇,氨体系中,化学反应生成4-溴邻苯二胺
参考文献:Wurster,Chemische Berichte,1873,Vol. 6,P. 1544
标题:Wurster,Chemische Berichte,1873,Vol. 6,P. 1544

专利信息

专利号:US-4336383-A
优先权日:1980-05-07
标题:1-1-Binaphthyl-4,4',5,5',8,8'-hexacarboxylic acid compounds, method of preparation and use thereof for the synthesis of asymmetric derivatives of 3,4,9,10-perylenetetracarboxylic acid, and for dyeing and printing of textile materials
发明人：VOROZHTSOV GEORGY N; MASANOVA NATALIA N; FELDBLJUM NIKOLAI B; ALEXEEV VASILY I; SHIGALEVSKY VADIM A; SOLOMATIN GEORGY G; SHULEPOVA OLGA I; KHAITUN GALINA G; GORDEEVA NADEZHDA V
权利人:VOROZHTSOV GEORGY N; MASANOVA NATALIA N; FELDBLJUM NIKOLAI B; ALEXEEV VASILY I; SHIGALEVSKY VADIM A; SOLOMATIN GEORGY G; SHULEPOVA OLGA I; KHAITUN GALINA G; GORDEEVA NADEZHDA V
摘要:1,1'-Binaphthyl-4,4',5,5',8,8'-hexacarboxylic acid compounds having the following formula: ##STR1## wherein R 1 is hydrogen, halogen, or alkyl; when X is oxygen, Y is hydrogen, alkyl, a cycloalkyl, or an aryl containing at least one substituent from the group including: halogen, alkyl, or alkoxy, when X is nitrogen, Y is ##STR2## wherein R 2 is hydrogen, halogen, or alkyl; Y being linked to X with the formation of a benzimidazole cycle. n The method for preparing the compounds according to the present invention resides in the treatment of that 1,1'-binaphthyl-4,4',5,5',8,8'-hexacarboxylic acid anhydride with an alkali to give a corresponding salt which is condensed with orthophenylenediamines upon heating at reflux at a pH of from 6.3 to 6.8. The resulting benzimidazole-1,1'-binaphthyl-4,4',5,5',8,8'-hexacarboxylic acid anhydride having the formula: ##STR3## wherein R 1 is hydrogen, halogen, or alkyl, is isolated and condensed with an amine or ortho-phenylenediamines in an excess of the amine, in water or an organic solvent, followed by isolation of the desired product. n The compounds according to the present invention are employed for the synthesis of asymmetric compounds of 3,4,9,10-perylenetetracarboxylic acid, as well as for dyeing and printing of textile materials with the formation, on the material, of asymmetric compounds of 3,4,9,10-perylenetetracarboxylic acid having the following formula: ##STR4## wherein R 1 is hydrogen, halogen, or alkyl; when X is oxygen, Y is hydrogen, alkyl, cycloalkyl, or aryl containing at least one substituent from the group including; halogen, alkyl, or alkoxy, when X is nitrogen, Y is ##STR5## where R 2 is hydrogen, halogen, or alkyl; Y being linked with X to form a benzimidazole cycle. n The compounds according to the present invention dye textile materials to various shades of violet color.

专利号:WO-2017021270-A1
优先权日:2015-08-03
标 题 :Process for the synthesis of ravidasvir
发明人：CASTALDI GRAZIANO; BARUTO ALESSANDRO; OLDANI ERMINIO; GABOARDI MAURO
权利人:HC-PHARMA AG
摘要:A process for the synthesis of ravidasvir and intermediates useful in the preparation thereof are disclosed.

专利号:US-2022356182-A1
优先权日:2009-03-27
标题 :Inhibitors of hepatitis c virus replication
发明人：COBURN CRAIG A; LUDMERER STEVEN W; LIU KUN; WU HAO; SOLL RICHARD; ZHONG BIN; ZHU JIAN
权利人:MERCK SHARP & DOHME
摘要:The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

专利号:US-9718807-B2
优先权日:2012-06-05
标 题 :Synthesis of antiviral compound
发明人：SCOTT ROBERT WILLIAM; VITALE JUSTIN PHILIP; MATTHEWS KENNETH STANLEY; TERESK MARTIN GERALD; FORMELLA ALEXANDRA; EVANS JARED WAYNE
权利人:GILEAD PHARMASSET LLC
摘要:The present disclosure provides processes for the preparation of a compound of formula I: n nwhich is useful as an antiviral agent. The disclosure also provides compounds that are synthetic intermediates to compounds of formula I.

专利号:US-11053243-B2
优先权日:2009-03-27
标 题:Inhibitors of hepatitis C virus replication
发明人：COBURN CRAIG A; LUDMERER STEVEN W; LIU KUN; WU HAO; SOIL RICHARD; ZHONG BIN; ZHU JIAN
权利人:MERCK SHARP & DOHME
摘要:The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

专利号:US-9090661-B2
优先权日:2009-03-27
标 题:Inhibitors of hepatitis C virus replication
发明人：COBURN CRAIG A; MCCAULEY JOHN A; LUDMERER STEVEN W; LIU KUN; VACCA JOSEPH P; WU HAO; HU BIN; SOLL RICHARD; SUN FEI; WANG XINGHAI; YAN MAN; ZHANG CHENGREN; ZHENG MINGWEI; ZHONG BIN; ZHU JIAN
权利人:MERCK SHARP & DOHME
摘要:The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.