CAS: 3042-81-7; Methyl Alpha-Bromophenylacetate

上下游产品

methanol bromo(phenyl)acetyl chloride phenylacetic acid 1,1-dimethoxy-2-phenylethene(2,5-dimethyl-4-oxo-piperidino)-phenyl-acetic acid methyl ester (2-methoxycarbonyl-ethylsulfanyl)-phenyl-acetic acid methyl ester 4-methyl-3-phenylmorpholin-2-one R)-7-oxo-3-phenoxymethyl-(1rH,5cH)-4-thia-2,6-diaza-bicyclo[3.2.0]hept-2-en-6-yl)-phenyl-acetic acid methyl ester(Ξ)-((1R)-7-oxo-3-phenoxymethyl-(1rH,5cH)-4-thia-2,6-diaza-bicyclo[3.2.0]hept-2-en-6-yl)-phenyl-acetic acid methyl ester

苯乙酸甲酯置于n-溴代丁二酰亚胺(Nbs),过氧化苯甲酰体系中,用 四氯化碳 作为反应溶剂,化学反应 4.0H,以84%的收率获得产物α-溴苯乙酸甲酯
参考文献:新型 4,5-二氢-3(2H)-哒嗪酮衍生物的合成
标题:新型 4,5-二氢-3(2H)-哒嗪酮衍生物的合成
摘要:摘要 已经制备了一系列结构上与衍生自 4,5-二氢-3(2H)-哒嗪酮的非肽类血管紧张素 Ii (Aii) 受体拮抗剂相关的新型化合物.在这些化合物中,间隔基与杂环的 C4 相连.
DOI:10.1081/scc-120028351

专利信息

专利号:US-6495693-B2
优先权日:1996-11-22
标题:N-(aryl/heteroaryl) amino acid derivatives, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
发明人：AUDIA JAMES E; FOLMER BEVERLY K; JOHN VARGHESE; LATIMER LEE H; NISSEN JEFFREY S; PORTER WARREN J; THORSETT EUGENE D; WU JING
权利人:ATHENA NEUROSCIENCES INC; LILLY CO ELI
摘要:Disclosed are compounds which inhibit beta-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits beta-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

专利号:US-9156840-B2
优先权日:2010-06-18
标题:D2 antagonists, methods of synthesis and methods of use
发明人：LUEHR GARY W; SUNDARAM ARATHI; JAISHANKAR PRIYADARSHINI; PAYNE PHILIP W; DRUZGALA PASCAL
权利人:ALTOS THERAPEUTICS LLC
摘要:Provided are D 2 or D 3 antagonist compounds and pharmaceutical compositions of formula I n nand pharmaceutically acceptable salts thereof, or isomers thereof, wherein R 1 , R 2 and R 3 are as defined herein. The invention further comprises methods for making the compounds of the invention and methods for the treatment of conditions mediated by the dopamine D 2 or D 3 receptor from the compounds of the invention.

专利号:US-8445610-B2
优先权日:2008-03-07
标题:Controlled radical polymerization processes
发明人：KWAK YUNGWAN; NICOLAY RENAUD; MATYJASZEWSKI KRZYSZTOF
权利人:KWAK YUNGWAN; NICOLAY RENAUD; MATYJASZEWSKI KRZYSZTOF; UNIV CARNEGIE MELLON
摘要:A transition metal mediated chain transfer agent controlled polymerization process is described. The process combines the advantages of atom transfer radical polymerization (ATRP) and reversible addition fragmentation transfer (RAFT) polymerization. Synthesis of chain transfer agents useful in the disclosed processes is also disclosed. Other improvements on ATRP RAFT processes are also described.

专利号:EA-002100-B1
优先权日:1996-12-23
标题:CYCLOALCYL COMPOUNDS, LACTAMS, LACTONES AND RELATED COMPOUNDS CONTAINING THEIR PHARMACEUTICAL COMPOSITIONS AND METHODS OF INHIBITING THE SURVIVAL AND / OR SYNTHESIS OF β-AMYLOUS PEPTIDE SOFTWARE AGREED SOFTWARE, SOFTWARE, SOFTWARE, SOFTWARE, SOFTWARE, SOFTWARE, SOFTWARE, SOFTWARE, SOFTWARE, SOFTWARE, SOFTWARE AND SOFTWORK

专利号:CN-119819362-A
优先权日:2025-01-03
标题 :A photocatalyst for the efficient catalytic synthesis of halogenated aromatic hydrocarbons and its preparation method and application

专利号:US-2014350005-A1
优先权日:2010-06-18
标题 :D2 antagonists, methods of synthesis and methods of use