CAS: 31106-82-8; 2-(Bromomethyl)Pyridine Hydrobromide

相似化合物

68470-59-7 7703-74-4 2089315-69-3

上下游产品

CAS号100-55-0 3-吡啶甲醇 | CAS号10035-10-6 氢溴酸 | CAS号55401-97-3 2-溴甲基吡啶 | CAS号1314118-94-9 MK2-IN-1盐酸盐 | CAS号1539-42-0 2,2'-二吡啶甲基胺 | CAS号16858-01-8 三(2-吡啶甲基)胺 | CAS号170364-57-5 恩扎妥林 | CAS号1620-50-4 2-[(Phenylsulfo...

2-吡啶甲醇置于氢溴酸,溶剂黄146体系中,化学反应 20.0H,以74%的收率获得2-(溴甲基)吡啶氢溴酸盐
参考文献:フェノール系化合物の製造方法
标题:フェノール系化合物の製造方法
摘要:提供一种直接氧化芳香族化合物以高效制备酚类化合物的方法.在二核镍配合物存在下,通过氧化剂氧化芳香族化合物以制备酚类化合物,所述化合物由以下式(i)或(II)表示.[选择图]无

专利信息

专利号:US-2024335827-A1
优先权日:2021-06-25
标题 :Iron-based complexes for use in the catalysis of hydrosilylation reactions
发明人：Song datong; LIANG QIUMING; JIMENEZ SANTIAGO JOSÉ LUIS
权利人:GOVERNING COUNCIL UNIV TORONTO
摘要:There is provided an iron-based complex of formula (IA) or (IB) or a solvate thereof (IA) (IB). The iron-based complex can be used for catalyzing a hydrosillation reaction, such as the hydrosilylation of a ketone or an aldehyde. Also provided is a method for preparing a silyl ether from a ketone or an aldehyde comprising the hydrosilylation of the ketone or aldehyde in the presence of the iron-based complex. Another method is provided for the synthesis of an alcohol from a ketone or an aldehyde comprising the hydrosilylation of the ketone or aldehyde in the presence of the iron-based complex to form a silyl ether, and then hydrolyzing the silyl ether to obtain the alcohol. A process for preparing the iron-based complex is further disclosed.

专利号:US-8476313-B2
优先权日:2004-08-26
标 题:Heteroaryl-containing isoflavones as aromatase inhibitors
发明人：BRUEGGEMEIER ROBERT W; KIM YOUNG-WOO; HACKETT JOHN C
权利人:BRUEGGEMEIER ROBERT W; KIM YOUNG-WOO; HACKETT JOHN C; UNIV OHIO STATE RES FOUND
摘要:Compounds and methods useful for treating and prevention of cancer, particularly hormone-dependent breast cancer. Provided are compounds of formula I: n nwherein X is selected from O, N, S, SO, SO 2 , and S(CH 2 ) n , wherein n=1-10; R 1 and R 2 may be the same or different and are selected from H, OH, OCH 3 , OCH 2 CH 3 , OCH 2 C 6 H 5 , NH 2 , NHCH 3 , N(CH 3 ) 2 , CH 3 , CH 2 CH 3 , CH 2 CH 2 CH 3 , CH(CH 3 ) 2 , C(CH 3 ) 3 , NO 2 , F, Cl, Br, CF 3 , SH, SCH 3 , SCH 2 CH 3 , OCOCH 3 , OCOC(CH 3 ) 3 , OCOCH 2 COOH, and CN; and R 3 is a nitrogen-containing heterocyclic ring. Also provided are method for treating or preventing cancer in a subject by administering a therapeutically effective amount of a heteroaryl-containing isoflavone, or a pharmaceutically acceptable salt or prodrug thereof, to a subject in need of treatment. Also provided is a method for the synthesis of 2-substituted isoflavones by first reacting deoxybenzoins with a phase transfer catalyst to provide a 2-(alkylthio)isoflavone; second deprotecting the 2-(alkylthio)isoflavone; and third applying selective debenzylation to form the final compound.

专利号:EP-2300484-B1
优先权日:2008-05-05
标题:Novel class of spiro piperidines for the treatment of neurodegenerative diseases
发明人：BRODNEY MICHAEL AARON; HELAL CHRISTOPHER JOHN; O'NEILL BRIAN THOMAS
权利人:PFIZER
摘要:Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula (I) as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

专利号:WO-2010096722-A1
优先权日:2009-02-20
标 题 :3-oxo-2, 3-dihydro- [1,2, 4] triazolo [4, 3-a]pyridines as soluble epoxide hydrolase (seh) inhibitors
发明人：FENG JUN; KEUNG WALTER; NOTZ WOLFGANG REINHARD LUDWIG
权利人:TAKEDA PHARMACEUTICAL; FENG JUN; KEUNG WALTER; NOTZ WOLFGANG REINHARD LUDWIG
摘要:Claimed are intermediates in the synthesis of N-Arylmethyl-3-Oxo-2,3-dihydro- [1,2,4]triazolo[4,3-a]pyridine-6-carboxamides as well as a process (A) to arrive at 3-Oxo-2, 3-dihydro-[1,2,4]triazolo[4,3-a]pyridine-6-carboxylic acid. The triazolo[4,3-a]pyridine-6-carboxamides of formula (I) are used as soluble epoxide hydrolase inhibitors (sEH) having therapeutic effect in pathologic conditions such as hypertension, stroke, inflammatory processes, diabetes and a variety of cardiovascular diseases.

专利号:DE-102016012162-A1
优先权日:2016-10-11
标题:Synthesis and structure of chemically switchable fluorescence probes based on amino acids

专利号:US-12421206-B2
优先权日:2018-07-09
标 题 :Aryl-n-aryl derivatives for treating a RNA virus infection
发明人：SCHERRER DIDIER; TAZI JAMAL; MAHUTEAU-BETZER FLORENCE; NAJMAN ROMAIN; SANTO JULIEN; APOLIT CÉCILE
权利人:ABIVAX; CENTRE NAT RECH SCIENT; UNIV MONTPELLIER; INST CURIE
摘要:A compound of formula (Ie):wherein Y1 represents an aryl group, X2 represents a —O— group, a —NH— group, a —S— group, a —CO—NH— group, a —NH—CO—NH— group, a —NH—CO— group, a —CH(OH)— group, a —CH(COOH)NH— group, a —CH(COOCH3)NH— group, a —C(OH)(CH2OH)—, agroup, a divalent 5-membered heteroaromatic ring comprising 1, 2, 3 or heteroatoms, a —SO2— group, or a —SO2—NH— group, Y2 represents a hydrogen atom, a hydroxyl group, a (C1-C4)alkoxy group, a —CHC(OH)2, a COORf, wherein Rf represents a hydrogen atom or a (C1-C4)alkyl group, a morpholinyl group, a dihydropyranyl group, agroup, agroup, a —PO(ORf)(OR′f) group, wherein Rf and R′f independently represents a hydrogen atom or a (C1-C4)alkyl group, an oxetanyl group, a —Si(CH3)3 group, a —NHCOO—(C1-C4)alkyl group, or a —CR1R2R3 group, or any of its pharmaceutically acceptable salt and pharmaceutical compositions containing them and to synthesis process for manufacturing them.