CAS: 608-08-2; 3-Indolyl Acetate

上下游产品

CAS号26340-47-6 3-碘代-1H-吲哚 | CAS号563-63-3 乙酸银 | CAS号120-72-9 吲哚 | CAS号3240-34-4 碘苯二乙酸 | CAS号480-93-3 3-羟基吲哚 | CAS号108-24-7 乙酸酐 | CAS号2570-63-0 乙酸铊 | CAS号67790-18-5 3-methoxycarbon... | CAS号100063-39-6 2-Acetyl-1H-ind... | CAS号6245-93-8 3-羟基-1H-吲哚-2-羧酸 | CAS号479-41-4 靛玉红 | CAS号91-56-5 靛红 | CAS号482-89-3 靛蓝 | CAS号248243-85-8 2-(1H-pyrrol-2-... | CAS号139582-54-0 6-MONOBROMOINDIGO | CAS号16800-67-2 N,O-1,3-二乙酰基吲哚 | CAS号16800-68-3 N-乙酰基-3-吲哚啉酮

3-羟基-1H-吲哚-2-羧酸置于水体系中,化学反应生成 吲哚乙酸酯
参考文献:Vorlaender; Drescher,Chemische Berichte,1901,Vol. 34,P. 1856
标题:Vorlaender; Drescher,Chemische Berichte,1901,Vol. 34,P. 1856

专利信息

专利号:US-11274081-B2
优先权日:2016-05-30
标 题:Process for the synthesis of ivacaftor
发明人：REDDY DUMBALA SRINIVASA; KULKARNI AMOL ARVIND; NATARAJAN VASUDEVAN; SHARMA MRITYUNJAY KESHAVPRASAD
权利人:COUNCIL SCIENT IND RES
摘要:The present disclosed an improved process for the synthesis of ivacaftor starting from indole acetic acid ester which can be performed in batch as well as continuous flow synthesis. The present invention further disclosed to a continuous process for the synthesis of compound of formula (II) or formula (III) from compound of formula (I) in continuous flow reactor.

专利号:US-7241900-B2
优先权日:2002-02-12
标题 :Synthesis of indole thiazole compounds as ligands for the Ah receptor
发明人：DELUCA HECTOR F; GRZYWACZ PAWEL K; SICINSKI RAFAL R
权利人:WISCONSIN ALUMNI RES FOUND
摘要:A method of synthesizing aromatic ketone compositions of formula I comprising the step of introducing a double bond into the 5 membered ring of the 4,5-dihydro-1,3-azoles moiety of formula II is disclosed. A method of synthesizing aromatic ketone compositions of formula I comprising the step of ring synthesis of the tetrahydro-1,3-azoles of formula XI is also disclosed.

专利号:US-10336703-B2
优先权日:2015-05-12
标题 :Process for the synthesis of ivacaftor and related compounds
发明人：REDDY DUMBALA SRINIVASA; NATARAJAN VASUDEVAN; JACHAK GORAKHNATH RAJARAM
权利人:COUNCIL SCIENT IND RES
摘要:The present patent discloses a novel one pot two-step process for the synthesis of ivacaftor and related compounds of [Formula (I)], wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 and Ar 1 are as described above; its tautomers or pharmaceutically acceptable salts thereof starting from indole acetic acid amides.

专利号:WO-2023284262-A1
优先权日:2021-07-13
标 题 :3,4-fused seven-membered heterocyclic oxindole, synthesis method therefor and application thereof
发明人：Li shuai-shuai; HU FANGZHI; Ding Zhanshuai; LI XINYAO
权利人:UNIV QINGDAO AGRICULTURAL
摘要:Disclosed is a 3,4-fused seven-membered heterocyclic oxindole, a synthesis method therefor and an application thereof. A structure of a 3,4-fused seven-membered nitrogen heterocyclic oxindole is provided in the present invention. A method for synthesizing same is also provided, comprising the following steps: reacting propargyl alcohol containing an isatin framework with a nucleophile under specific conditions to prepare a 3,4-fused seven-membered nitrogen heterocyclic oxindole. A pharmaceutical composition is provided in the present invention. Also provided in the present invention is an application of a 3,4-fused seven-membered nitrogen heterocyclic oxindole in the preparation of a drug for treating cancer. Provided in the present invention is a method for efficiently synthesizing 3,4-fused seven-membered nitrogen heterocyclic oxindoles having different structures. This is the first time achieving efficient synthesis of bioactive molecules containing both benzazepine and 3,4-fused heterooxidized oxindole structures on the basis of a hydrogen migration strategy.

专利号:US-4868304-A
优先权日:1988-05-27
标题 :Synthesis of nitrogen heterocycles
发明人：LAROK RICHARD C; BABU SRINIVASAN
权利人:UNIV IOWA STATE RES FOUND INC
摘要:A method of synthesizing nitrogen heterocycles such as indoles, indolines, oxindoles, quinolines, isoquinolines, and isoquinolones, all of which are pharmacologically active. The method involves cyclizing a haloaryl alkene in the presence of a catalytically effective amount of a palladium(II) ion source and in the presence of a cyclizing promoting base such as an alkali metal salt.

专利号:US-8816106-B2
优先权日:2006-08-29
标 题:Synthesis of fatty acids
发明人：DAMCEVSKI KATHERINE; GLOVER KAREN; GREEN ALLAN; HARITOS VICTORIA S; HORNE IRENE; SINGH SURINDER PAL; WOOD CRAIG C; ZHOU XUE-RONG
权利人:DAMCEVSKI KATHERINE; GLOVER KAREN; GREEN ALLAN; HARITOS VICTORIA S; HORNE IRENE; SINGH SURINDER PAL; WOOD CRAIG C; ZHOU XUE-RONG; COMMW SCIENT IND RES ORG; GRAINS RES & DEV CORP
摘要:The present invention relates to enzymes which possess desaturase, conjugase, epoxidase and/or hydroxylase activity that can be used in methods of synthesizing fatty acids.