CAS: 198206-33-6; 1-Iodo-3-(Trifluoromethoxy)Benzene

该化合物是有机碘化合物,其特点是存在一个碘原子和三氟甲基苯氧组(O-CF3),并附于苯环;该化合物通常显示一种分子结构,碘原子与与与三氟甲基苯氧基替代结构相对的元体位置的芳香环结合在一起;三氟甲基苯基组因其电镀性能而闻名,可影响化合物的再活性和稳定性;3-(三氟甲基苯氧)二苯基经常用于有机合成和药用化学,特别是制药和农用化学的开发;其独特的特性,如氟原子产生的高电能性能,可增强化合物在核聚苯乙烯替代反应中的再活性;此外,碘的存在可促进各种联动反应,使其成为合成途径中有价值的中间体.与许多有机碘化合物一样,处理应注意与含氟化合物和含氟化合物相关的化合物.

英文名称1-Iodo-3-(Trifluoromethoxy)Benzene
中文名称1-碘-3-(三氟甲氧基)苯
IUPAC名称1-iodo-3-(trifluoromethoxy)benzene
其它别名3-(Trifluoromethoxy)Iodobenzene; 3-Iodo-1-(Trifluoromethoxy)Benzene; 3-Trifluoromethoxyiodobenzene; 1-Iodo-3-(Trifluoromethoxy)Benzene; 1-Iodo-3-Trifluoromethoxy-Benzene
CAS编号198206-33-6
MFCD编号:MFCD01090992
EINECS号:672-153-7
分子式:C7H4F3IO
分子量:288.01
产品CID: 1008714
产品分类有机原料→分子砌块→芳环类化合物→苯类化合物

相似结构搜索
InChIKey: UQZXQSQWKJZHCD-UHFFFAOYSA-N
InChI=1S/C7H4F3IO/c8-7(9,10)12-6-3-1-2-5(11)4-6/h1-4H…
计算化学: 氢键受体数1.0氢键供体数0.0可旋转键数1.0

MSDS等安全信息

GHS象形图
GHS符号GHS07;
注释: Exclamation mark
危险类别特定目标器官毒性 - 单次接触类别3
皮肤腐蚀/刺激类别2
严重眼刺激类别2
警示词Warning(警告)
危险描述H335 |可能引起呼吸道刺激.
H315 |造成皮肤刺激.
H319 |造成严重眼刺激.
防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
UN编号UN 1993 3/PG 3
危险品标志Xi
风险等级Irritant
安全声明26-36-37
危险类别码36/37/38
WGK Germany3

欧盟法规

ECHA物质C&L通报

上下游产品

CAS号1535-73-5 3-三氟甲氧基苯胺 | CAS号2252-44-0 1-溴-3-(三氟甲氧基)苯

合成工艺路线路线简述

3-三氟甲氧基苯胺置于硫酸,Sodium Nitrite,Potassium Iodide体系中,用水用作溶剂,化学反应 0.25H,以14%的收率获得3-(三氟甲氧基)碘苯
参考文献:Wo2006/55187
标题:Wo2006/55187

海关参考信息

2905110000-甲醇
2908199090-其他酚的卤化衍生物
2908999090-其他酚的硝化衍生物
2918290000-其他含酚基羧酸
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

专利号:US-7884125-B2
优先权日:2008-04-30
标题:Straightforward entry to 7-azabicyclo[2.2.1]heptane-1-carbonitriles and subsequent synthesis of epibatidine analogues
发明人：STEVENS CHRISTIAN; HEUGEBAERT THOMAS
权利人:UNIV GENT
摘要:The present invention relates to a group of substituted-7-azabicyclo-[2.2.1]heptyl derivatives with biological activity. The present invention also relates to synthetic methods for producing said substituted-7-azabicyclo-[2.2.1]heptyl derivatives. The present invention also relates to certain intermediates for producing such substituted-7-azabicyclo-[2.2.1]heptyl derivatives, as well as a synthetic method for producing such intermediates. The present invention also relates to pharmaceutical compositions comprising such substituted-7-azabicyclo-[2.2.1]heptyl derivatives, as well as their use as medicaments for the treatment of diseases mediated by a Nicotinic Acetylcholine Receptor or a receptor being a member of the Neurotransmitter-gated Ion Channel Superfamily, such as pain, Alzheimer's disease, Parkinson's disease, schizophrenia, epilepsy and nicotine addiction.

专利号:US-12227528-B2
优先权日:2017-11-09
标题:Glucose-sensitive albumin-binding derivatives
发明人：KRUSE THOMAS; KOFOD-HANSEN MIKAEL; MUENZEL MARTIN WERNER BORCHSENIUS; THOEGERSEN HENNING; SAUERBERG PER; EWALD JAKOB; BEHRENS CARSTEN; HOEG-JENSEN THOMAS; BALSANEK VOJTECH; DROBNAKOVA ZUZANA; DROZ LADISLAV; HAVRANEK MIROSLAV; KOTEK VLADISLAV; STENGL MILAN; SNAJDR IVAN; DRUSANOVA HANA
权利人:NOVO NORDISK AS
摘要:This invention relates to glucose-sensitive albumin-binding diboron conjugates. More particularly the invention provides novel diboron compounds, and in particular diboronate or diboroxole compounds, useful as intermediate compounds for the synthesis of diboron conjugates.

专利号:US-2009275616-A1
优先权日:2008-04-30
标题 :Straightforward entry to 7-azabicyclo[2.2.1]heptane-1-carbonitriles and subsequent synthesis of epibatidine analogues

专利号:CN-118290284-A
优先权日:2024-04-02
标题 :Synthesis method and application of alpha-carbonyl amide compound