CAS: 22398-14-7; Dimethyl Methoxymethylenemalonate

相似化合物

17041-60-0 87-13-8 41530-32-9

上下游产品

CAS号27931-91-5 dimethyl (hydro... | CAS号108-59-8 丙二酸二甲酯 | CAS号149-73-5 原甲酸三甲酯 | CAS号104286-69-3 dimethyl 4-meth... | CAS号18856-69-4 dimethyl 2-(dim... | CAS号27931-91-5 dimethyl (hydro... | CAS号108-59-8 丙二酸二甲酯 | CAS号104286-70-6 dimethyl 2-meth... | CAS号85531-80-2 2-氧代-5,6,7,8-四氢... | CAS号88456-30-8 dimethyl 2-(ace... | CAS号942227-34-1 1,4-二氢-6-甲氧基-4-... | CAS号51534-81-7 dimethyl 2-(2,2...

Dimethyl (Hydroxymethylene)Malonate置于盐酸体系中,用 甲醇,二氯甲烷,乙腈 用作溶剂,化学反应生成甲氧基亚甲基马来酸二甲酯
参考文献:Method For The Preparation Of Alkoxymethylene Compounds Of Acetic Esters
标题:Method For The Preparation Of Alkoxymethylene Compounds Of Acetic Esters
摘要:公开了一种制备烷氧甲基化合物的方法,特别是从取代或未取代的乙酸烷基酯,特别是甲酯,制备甲氧甲基化合物,从相应的羟甲基化合物或其碱盐,通过与过量的烷醇,特别是甲醇,在hcl和水结合剂的存在下反应.首选与水形成稳定反应产物的水结合剂.

专利信息

专利号:US-5254558-A
优先权日:1991-08-15
标 题:Substituted 1,3-diazines as leukocyte elastase inhibitors
发明人：BERNSTEIN PETER R; EDWARDS PHILIP D; THOMAS ROYSTON M; VEALE CHRIS A; WARNER PETER; WOLANIN DONALD J
权利人:ICI PLC
摘要:The present invention relates to certain novel substituted heterocycles which are 1-pyrimidinylacetamide compounds of formula I, set out herein, which are inhibitors of human leukocyte elastase (HLE), also known as human neutrophil elastase (HNE), making them useful whenever such inhibition is desired, such as for research tools in pharmacological, diagnostic and related studies and in the treatment of diseases in mammals in which HLE is implicated. The invention also includes intermediates useful in the synthesis of these substituted heterocycles, processes for preparing the substituted heterocycles, pharmaceutical compositions containing such substituted heterocycles and methods for their use.

专利号:WO-9321213-A1
优先权日:1992-04-16
标题 :Alpha-aminoboronic acid peptides and their use as elastase inhibitors
发明人：BERNSTEIN PETER ROBERT; SHAW ANDREW; SHENVI ASHOKKUMAR BHIKKAPPA; THOMAS ROYSTON MARTIN; WARNER PETER; WOLANIN DONALD JOHN
权利人:ZENECA LTD
摘要:The present invention relates to certain novel heterocyclic derivatives which are 1-pyridylacetamide derivatives of formula (I), set out herein, which are inhibitors of human leukocyte elastase (HLE), also known as human neutrophil elastase (HNE), making them useful whenever such inhibition is desired, such as for research tools in pharmacological, diagnostic and related studies and in the treatment of diseases on mammals in which (HLE) is implicated. The invention also includes intermediates useful in the synthesis of these heterocyclic derivatives, processes for preparing the heterocyclic derivatives, pharmaceutical compositions containing such heterocyclic derivatives and methods for their use.

专利号:US-5721222-A
优先权日:1992-04-16
标 题 :Heterocyclic ketones
发明人：BERNSTEIN PETER ROBERT; SHAW ANDREW; THOMAS ROYSTON MARTIN; VEALE CHRIS ALLAN; WARNER PETER; WOLANIN DONALD JOHN
权利人:ZENECA LTD
摘要:The present invention relates to certain novel heterocyclic ketones which are 1-pyridylacetamide ketones of formula I, set out herein, which are inhibitors of human leukocyte elastase (HLE), also known as human neutrophil elastase (HNE), making them useful whenever such inhibition is desired, such as for research tools in pharmacological, diagnostic and related studies and in the treatment of diseases in mammals in which HLE is implicated. The invention also includes intermediates useful in the synthesis of these heterocyclic ketones, processes for preparing the heterocyclic ketones, pharmaceutical compositions containing such heterocyclic ketones and methods for their use.

专利号:US-5521179-A
优先权日:1991-04-18
标题 :Heterocyclic amides
发明人：BERNSTEIN PETER R; SHAW ANDREW; THOMAS ROYSTON M; WARNER PETER; WOLANIN DONALD J
权利人:ZENECA LTD
摘要:The present invention relates to certain novel heterocyclic amides which are 1-pyridylacetamide compounds of formula I, set out herein, which are inhibitors of human leukocyte elastase (HLE), also known as human neutrophil elastase (HNE), making them useful whenever such inhibition is desired, such as for research tools in pharmacological, diagnostic and related studies and in the treatment of diseases in mammals in which HLE is implicated. The invention also includes intermediates useful in the synthesis of these heterocyclic amides, processes for preparing the heterocyclic amides, pharmaceutical compositions containing such heterocyclic amides and methods for their use.

专利号:US-3515745-A
优先权日:1967-10-05
标 题:Synthesis of arylamino methylenemalonates
发明人：TULL ROGER J; WEINSTOCK LEONARD M; MULVEY DENNIS M
权利人:MERCK & CO INC

专利号:CN-111116310-B
优先权日:2018-10-30
标题:Asymmetric synthesis method of Vinigrol