CAS: 446-35-5; 2,4-Difluoro-1-Nitrobenzene

上下游产品

CAS号611-06-3 2,4-二氯硝基苯 | CAS号367-25-9 2,4-二氟苯胺 | CAS号56022-38-9 triethyl(hexade... | CAS号126-33-0 环丁砜 | CAS号2751-90-8 四苯基溴化磷 | CAS号148854-10-8 (2,4-二氟苯基)三甲基硅烷 | CAS号2369-13-3 3-氟-4-硝基苯胺 | CAS号372-18-9 1,3-二氟苯 | CAS号55687-23-5 6-氟喹喔啉-2-(1H)-酮 | CAS号4920-84-7 2,4-二甲氧基硝基苯 | CAS号446-38-8 3-氟-4-硝基苯甲醚 | CAS号448-19-1 5-氟-2-硝基苯甲醚 | CAS号52807-12-2 4-羟基氟吡洛芬 | CAS号315228-19-4 2-氟-4-硝基苯乙酸 | CAS号55687-33-7 2-氯-6-氟喹喔啉 | CAS号367-25-9 2,4-二氟苯胺 | CAS号367-27-1 2,4-二氟苯酚 | CAS号345-24-4 2,4-二氟-5-溴硝基苯

2-氟-4-溴硝基苯置于15-冠醚-5,Sodium Fluoride体系中,用 Neat (No Solvent) 作为反应溶剂,以90%的收率获得产物2,4-二氟硝基苯
参考文献:一种含氟芳基化合物的制备方法
标题:一种含氟芳基化合物的制备方法
摘要:本发明涉及有机合成领域,特别是涉及一种含氟芳基化合物的制备方法.本发明提供一种式1化合物的制备方法,包括:氟化反应:将式2化合物在相转移催化剂存在的条件下与碱金属氟化物反应制备获得式1化合物.本发明所提供的含氟芳基化合物的制备方法,反应体系中不包括溶剂,且相转移催化剂沸点较高,反应结束后精馏或短蒸时无溶剂干扰,蒸馏收率高,产品纯度好.

专利信息

专利号:US-5354439-A
优先权日:1990-07-16
标 题 :Process for the synthesis of fluorinated derivatives
发明人：FORAT GERARD; GILBERT LAURENT; LANGLOIS BERNARD
权利人:RHONE POULENC CHIMIE
摘要:A process for the synthesis of fluorinated organic compounds and a reagent suitable for use in the process. The process is carried out by exchange with fluorides, while preferably agitating the reaction medium with ultrasonic sound.

专利号:US-2023399302-A1
优先权日:2020-10-29
标题:Process for the preparation of heteroaryl-substituted sulfur(vi) compounds
发明人：LOPCHUK JUSTIN M; SHULTZ ZACHARY P; SCATTOLIN THOMAS
权利人:H LEE MOFFITT CANCER CT & RES
摘要:The present disclosure provides processes for the synthesis of organic compounds, in particular processes for the synthesis of heteroaryl-substituted sulfur(VI) compounds by nucleophilic aromatic substitution.

专利号:US-7217842-B2
优先权日:2001-04-12
标题:Catalysts for nucleophilic substitution, synthesis thereof, composition containing them and use thereof
发明人：SCHANEN VINCENT; CRISTAU HENRI-JEAN; TAILLEFER MARC
权利人:RHONE POULENC CHIMIE
摘要:The invention concerns novel catalysts for aromatic nucleophilic substitution. Said catalysts are compounds of the general formula (I), wherein: R 1 , R 2 , R 3 , R 4 , R 5 , and R 6 , identical or different, are selected among hydrocarbon radicals; the Pn's, advantageously the same, are selected among metalloid elements of column V of a period higher than nitrogen; Z is a metalloid element of column V, advantageously distinct from Pn; preferably a nitrogen (N, P, As, Sb). The invention is applicable to organic synthesis

专利号:CN-110627738-A
优先权日:2019-10-23
标题 :A kind of synthetic method that is used for the synthesis of the pesticide intermediate of flurafen

专利号:CN-114031503-A
优先权日:2021-12-15
标 题:Method for the simultaneous synthesis of 5-fluoro-2-nitrophenol and 3-fluoro-4-nitrophenol

专利号:CN-111848695-B
优先权日:2019-04-29
标题:A catalyst and its application in the synthesis of aromatic fluorine compounds