CAS: 59113-36-9; Diglycerol

该化合物是一种化学化合物,其结构由两个甘油分子组成,由两个以酯质连接的甘油分子组成;一种无色,无味和粘粘液,具有湿度,可以吸收空气中的湿度;二甘油在水和酒精中溶解,可以多种用途;在化妆品和制药业中通常使用,作为抽取剂,溶解剂和溶剂,因为它能够保持水分,增强配方的质质;此外,狄氏素在食品中具有潜在用途,可以用作甜剂和稳定剂;其毒性低和生物兼容性,因此适合用于皮肤接触的产品;此外,狄氏素可以作为合成其他化学化合物的前体,有助于其在有机化学和工业过程中的重要性;总的来说,由于多种用途的多功能性和安全性,对地甘油具有价值.

结构式图片

欧盟法规

REACH注册ECHA物质C&L通报REACH预注册

合成工艺路线路线简述

    海关参考信息

    专利信息


    专利号:US-5571677-A
    优先权日:1993-07-02
    标题:Convergent synthesis of branched and multiply connected macromomolecular structures
    发明人:GRYAZNOV SERGEI M
    权利人:LYNX THERAPEUTICS INC
    摘要:The invention provides methods and compositons for convergent synthesis of branched polymers useful as molecular probes. The invention also includes several novel branched polymeric structures particularly useful for detecting target polynucleotides. Branched polymers of the invention comprise at least two branches: at least one branch is a target binding moiety capable of specifically binding to a target molecule of interest and one or more branches are signal generation moities capable of directly or indirectly generating a detectable signal. In accordance with the method of the invention branched polymers are assembled from components having phosphorothioate groups and/or haloacyl- or haloalkylamino groups. The phosphorothioate and haloacyl- or haloalkylamino groups react rapidly and efficiently when brought into contact to form thiophosphorylacyl- or thiophosphorylalkylamino bridges which.complete the assembly of a branched polymer. The method of the invention permits thorough purification and isolation of the components prior to final assembly. Incomplete branched polymers are readily separated from the desired product by standard means. The method of the invention permits the synthesis of several novel branched polymer configurations.

    专利号:US-5830658-A
    优先权日:1995-05-31
    标 题 :Convergent synthesis of branched and multiply connected macromolecular structures
    发明人:GRYAZNOV SERGEI M
    权利人:LYNX THERAPEUTICS INC
    摘要:The invention provides methods and compositons for convergent synthesis of branched polymers useful as molecular probes. The invention also includes several novel branched polymeric structures particularly useful for detecting target polynucleotides. Branched polymers of the invention comprise at least two branches: at least one branch is a target binding moiety capable of specifically binding to a target molecule of interest and one or more branches are signal generation moities capable of directly or indirectly generating a detectable signal. In accordance with the method of the invention branched polymers are assembled from components having phosphorothioate groups and/or haloacyl- or haloalkylamino groups. The phosphorothioate and haloacyl- or haloalkylamino groups react rapidly and efficiently when brought into contact to form thiophosphorylacyl- or thiophosphorylalkylamino bridges which complete the assembly of a branched polymer. The method of the invention permits thorough purification and isolation of the components prior to final assembly. Incomplete branched polymers are readily separated from the desired product by standard means. The method of the invention permits the synthesis of several novel branched polymer configurations.

    专利号:US-9950988-B2
    优先权日:2012-12-26
    标题:Method for the synthesis of alpha/alpha-prime-alcoxylated glycerol linear carbonic esters
    发明人:LEISING FRéDéRIC; MOULOUNGUI ZéPHIRIN
    权利人:CHRYSO; INST NAT POLYTECHNIQUE TOULOUSE; INST NAT DE LA RECH AGRONOMIQUE INRA
    摘要:A method for the synthesis of α/α′-alcoxylated glycerol linear carbonic esters, wherein the following are brought into contact at a reaction temperature lower than 220° C.: a quantity of at least one precursor selected from the group consisting of α/α′-alcoxylated glycerol cyclo-carbonates; a quantity of at least one catalyst selected from the group consisting of metal oxides, Lewis acids, organometallic catalysts and mineral bases; and a quantity of at least one organic primer. A composition containing at least one novel α/α′-alkoxylated glycerol linear carbonic ester.

    专利号:WO-2017137818-A1
    优先权日:2016-02-12
    标 题 :Synthesis and application of an antimicrobial active
    发明人:K RAKESH RATNAM; SARVIYA SAMIR
    权利人:SALICYLATES & CHEMICALS
    摘要:The disclosure Synthesis & Application of a Novel Antimicrobial active provides a method of synthesis of organic complex starting from fatty acid with a free base bioactive molecule containing nitrogen atoms. The reaction is usually conducted in refluxing alcohol. The product is synthesized by a acid-base reaction whereby the acid molecule is capable of donating a proton, to the free base molecule resulting in the formation of the desired complex. These complexes are very effective antimicrobial active against a variety of bacteria, fungi, protozoa, helminths and viruses. The process is suitable for large-scale synthesis and involves simple and high-yielding techno feasible chemical transformations using low-cost commercially available raw materials. The complex has wide spread use in human personal care, industries and household applications, as the disclosed chemical has antimicrobial activity against gram positive, gram negative bacteria, yeast, mold, fungi.

    专利号:WO-9617589-A1
    优先权日:1994-12-08
    标 题 :Method of smoothing or removing wrinkles and method of stimulating collagen synthesis
    发明人:FUJIMURA TSUTOMU; OGAWA AYUMI; OHSU HIROYUKI; TAKEMA YOSHINORI; HORI KIMIHIKO; AMANO SHINYA; FUJIMORI TAKETOSHI; OHASHI YUKIHIRO; SUZUKI YASUTO
    权利人:KAO CORP; FUJIMURA TSUTOMU; OGAWA AYUMI; OHSU HIROYUKI; TAKEMA YOSHINORI; HORI KIMIHIKO; AMANO SHINYA; FUJIMORI TAKETOSHI; OHASHI YUKIHIRO; SUZUKI YASUTO
    摘要:The present invention relates to methods of stimulating collagen synthesis and of smoothing or removing wrinkles, which comprise administering an effective amount of a benzoic acid derivative of formula (1) or a salt thereof, wherein X is -O- or -N(R4)- (R4 is H or the like), R1 is a C¿4-25?-alkyl or C4-25-alkenyl group, R?2¿ is H, OH, or a C¿1-6?-alkoxyl or C1-6-alkanoyloxy group, and R?3 is -OR5¿ or -N(R?6)R7 (R5? is H, or a C1-25-alkyl or C1-25-alkenyl group), and R?6 and R7¿ are individually H, or a C¿1-3?-alkyl or C1-3-alkenyl group, and use of this compound for agents for stimulating synthesis of collagen, and smoothing or removing wrinkles. This compound (1) stimulates collagen synthesis in human dermal fibroblasts and consequently smooths or removes wrinkles caused by aging and/or photoaging.

    专利号:WO-9531425-A1
    优先权日:1994-05-16
    标 题 :Novel co-ordinated metal/boron compounds as biocides, their methods of synthesis, their use and their formulation
    发明人:MAYNARD NIGEL PAUL
    权利人:MAYNARD NIGEL PAUL
    摘要:The invention includes the synthesis of multivalent metal complexes with boron containing complex organic anions. The complexes include or may include ligands. Complexes capable of being so synthesised are also disclosed as is their use as biocides which fix owing to low aqueous solubility. Intermediates of the process or complexes of the process (after heating or when provided with ligands low on the series) are also useful to strip multivalent metal cations or ligand forming compounds from an aqueous phase (usually by the movement of the complex with the attached multivalent metal cations or ligands into an organic solvent phase), thereby completing the synthesis.
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    合成参考文献


    摘要:S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118
    摘要:Final Report is Available from CIR 09/23
    参考文献:10.1007/bf02540966
    摘要:Herrmann H, Gercken G. Incorporation of [1‐14C]octadecanol into the lipids ofLeishmania donovani. Lipids. 1980 Mar;15(3):179–85. doi: 10.1007/bf02540966.
    参考文献:10.1023/b:jobb.0000019594.43450.c5
    摘要:Pflüger K, Müller V. Transport of Compatible Solutes in Extremophiles. Journal of Bioenergetics and Biomembranes. 2004 Feb;36(1):17–24. doi: 10.1023/b:jobb.0000019594.43450.c5.
    参考文献:10.1007/s00449-012-0874-2
    摘要:Ortega S, Máximo MF, Montiel MC, Murcia MD, Arnold G, Bastida J. Esterification of polyglycerol with polycondensed ricinoleic acid catalysed by immobilised Rhizopus oryzae lipase. Bioprocess and Biosystems Engineering. 2012 Dec 23;36(9):1291–302. doi: 10.1007/s00449-012-0874-2.
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