CAS: 18729-48-1; 3-Methylcyclopentan-1-Ol

该化合物是一种多用途循环酒精,其第三位位置为甲基替代成分,在有机溶剂中表现出极佳的溶解性,使它在广泛的合成应用中成为理想. 甲基组的存在增强了其反应性,促进了各种变异. 其循环结构有助于其稳定性,确保化学反应的可靠性能.

结构式图片

相似化合物

1462-03-9 1402842-91-4 1757-42-2

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

(R)-3-methylcyclopentanone 3-methyl-cyclopentanone 1-acetoxy-3-iodomethyl-cyclopentane 1,2-epoxy-5-hexene 3-methyl-1-cyclopentene methyl-cyclopentane 1-methylcyclopent-1-ene 1-chloro-3-methyl-cyclopentane

合成工艺路线路线简述

    1-Acetoxy-3-Iodomethyl-Cyclopentane置于lithium Aluminium Tetrahydride体系中,用 四氢呋喃 用作溶剂,化学反应生成3-甲基环戊醇
    参考文献:Julia,M.; Colomer,E.,Comptes Rendus Des Seances De L'Academie Des Sciences,Serie C: Sciences Chimiques,1970,Vol. 270,P. 1305-1307
    标题:Julia,M.; Colomer,E.,Comptes Rendus Des Seances De L'Academie Des Sciences,Serie C: Sciences Chimiques,1970,Vol. 270,P. 1305-1307

    海关参考信息

    专利信息


    专利号:US-5041637-A
    优先权日:1988-07-12
    标题:Process for the synthesis of optically active aminoacids
    发明人:CANNATA VINCENZO; TAMERLANI GIANCARLO; CALZOLARI CLAUDIO
    权利人:PRESIDENZA DEL CONSIGLIO DEL M
    摘要:New process for the synthesis of optically active aminoacids of formula ##STR1## by treating compounds of formula ##STR2## which an optically active alcohol of formula n n R.sub.4 --OH (III) n n n d or 1 n n To obtain a pair of diastereoiosmer esters of formula ##STR3## which is resolved in basic medium into the single diastereoisomer esters of formula ##STR4## from which the desired optically active aminoacid of formula (I) is obtained by treatment in acid medium.

    专利号:US-10975096-B2
    优先权日:2014-06-20
    标题 :Synthesis of polycyclic-carbamoylpyridone compounds
    发明人:CHIU ANNA; ENQUIST JR JOHN; GRIGGS NOLAN; HALE CHRISTOPHER; IKEMOTO NORIHIRO; KEATON KATIE ANN; KRAFT MATT; LAZERWITH SCOTT E; LEEMAN MICHEL; PENG ZHIHUI; SCHRIER KATE; TRINIDAD JONATHAN; VAN HERPT JOCHEM; WALTMAN ANDREW W
    权利人:GILEAD SCIENCES INC
    摘要:Methods of making compounds of Formula I are disclosed:

    专利号:US-9802952-B2
    优先权日:2013-07-15
    标 题:Method and apparatus for the synthesis of dihydroartemisinin and artemisinin derivatives
    发明人:KOPETZKI DANIEL; MCQUADE DAVID TYLER; SEEBERGER PETER H; GILMORE KERRY
    权利人:MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WSS E V; MAX-PLANK-GESELLSCHAFT ZUR FÖRDERUNG DER WSS E V
    摘要:The present invention is directed to a method for continuous production of dihydroartemisinin and also artemisinin derivatives derived from dihydroartemisinin by using artemisinin or dihydroartemisinic acid (DHAA) as starting material as well as to a continuous flow reactor for producing dihydroartemisinin as well as the artemisinin derivatives. It was found that the reduction of artemisinin to dihydroartemisinin in a continuous process requires a special kind of reactor and a special combination of reagents comprising a hydride reducing agent, at least one activator such as an inorganic activator, at least one solid base, at least one aprotic solvent and at least one C 1 -C 5 alcohol.

    专利号:US-5637757-A
    优先权日:1995-04-11
    标 题 :One-pot synthesis of ring-brominated benzoate compounds
    发明人:HILL JOHN E; FAVSTRITSKY NICOLAI A; MAMUZIC RASTKO I; BHATTACHARYA BHABATOSH
    权利人:GREAT LAKES CHEMICAL CORP
    摘要:A method of preparing tetrabromobenzoate compounds from tetrabromophthalic anhydride by reacting tetrabromophthalic anhydride with alcohol in the presence of a decarboxylation catalyst. The reaction may be carried out in an excess of alcohol, or with a near stoichiometric amount of alcohol by performing the reaction in an inert solvent.

    专利号:US-11292757-B2
    优先权日:2018-09-28
    标题:Synthesis of cyclopentenones
    发明人:PADILLA-ACEVEDO ANGELA I
    权利人:DOW GLOBAL TECHNOLOGIES LLC
    摘要:A method comprising synthesizing a substituted cyclopentenone compound via reaction of a substituted cycloalkyl acrylate ester in the presence of phosphorous pentoxide/methanesulfonic acid reagent to make the substituted cyclopentenone compound.

    专利号:US-9676783-B2
    优先权日:2008-10-22
    标 题:Method of treatment using substituted pyrazolo[1,5-A] pyrimidine compounds
    发明人:HAAS JULIA; ANDREWS STEVEN W; JIANG YUTONG; ZHANG GAN
    权利人:ARRAY BIOPHARMA INC
    摘要:Compounds useful in the synthesis of compounds for treating pain, cancer, inflammation, neurodegenerative disease or Typanosoma cruzi infection in a mammal.
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    主要参考文献

    [参考文献]: Mireia Oromí-Farrús, Et Al. Acylation Of Chiral Alcohols: A Simple Procedure For Chiral Gc Analysis. J Anal Methods Chem. 2012:2012:452949.

    合成参考文献


    摘要:von Angerer, S., Science of Synthesis, (2005) 26, 83.
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