CAS: 55611-39-7; N-Allylcyclopentanamine

相似化合物

45592-46-9 1394041-84-9 1176911-28-6

上下游产品

CAS号30533-03-0 N-Allylcyclopen... | CAS号120-92-3 环戊酮 | CAS号107-11-9 丙烯胺 | CAS号1003-03-8 环戊胺

N-Allylcyclopentylideneamine置于lithium Aluminium Tetrahydride体系中,用 乙醚 作为反应溶剂,化学反应 4.0H,以87%的收率获得产物n-烯丙基环戊基胺
参考文献:Lewis Acid-Promoted 3-Aza-Cope Rearrangement Of N-Alkyl-N-Allyl Enamines
标题:Lewis Acid-Promoted 3-Aza-Cope Rearrangement Of N-Alkyl-N-Allyl Enamines
摘要:The 3-Aza-Cope Rearrangement Of The N-Alkyl-N-Allylenamines Derived From Isobutyraldehyde,Which Proceeds Thermally At 250-Degrees-C,Has Been Accelerated By A Variety Of Electrophilic Reagents To Give Gamma,Delta-Unsaturated Imines. Protic Acids,Such As Hcl (0.5 Equiv),And The Lewis Acidic Reagents Ticl4 (0.1-0.2 Equiv),Et2O.Bf3 (0.5 Equiv),And Alme3 (1.0 Equiv) Produced Complete [3,3] Rearrangement Of Substrates At 111-Degrees-C. By Increasing The Lewis Acidity Of The Aluminum Reagents,This Transformation Was Achieved At 50-Degrees-C With Clalme2,Cl2Alme,And Methylaluminum Bis(2,6-Diphenylphenoxide). Reaction Conditions Were Studied Initially By Glc Analysis Of The N-Isobutyl Derivative. These Optimum Conditions Were Then Used To Obtain Isolated Yields Of 59-99% For Rearrangement And In Situ Lialh4 Reduction Of The Analogous N-Methylcyclohexyl Substrate To The Corresponding Delta,Epsilon-Unsaturated Amine. Substrates Derived From 2-Phenylpropanal,N-Butanal,Cyclohexanone,And Cyclopentanone Were Used To Examine The General Effectiveness Of Hcl,Ticl4,And Alme3 As Reagents For Acceleration Of The [3,3] Rearrangement. The Most Versatile And Efficient Reagent For Promoting This Reaction,Alme3,Produced Overall Yields Of 83-96% For The Two-Step Rearrangement And Reduction Of These Substrates.
DOI:10.1021/jo00028A016

专利信息

专利号:US-6384216-B1
优先权日:2000-08-09
标 题 :Purification of alkenyl compounds
发明人：LORENZ RUDOLF ERICH; BOETTCHER ARND; PINKOS ROLF
权利人:BASF AG
摘要:A process for purifying alkenyl compounds having a divalent or trivalent heteroatom in the alpha-position relative to the double bond by distillation comprises carrying out at least two distillations in which the purified alkenyl compounds are obtained from the gas phase by condensation, where the time between the first distillation after the synthesis of the alkenyl compounds and at least one further distillation is at least one day and the purified alkenyl compounds have an APHA color number of <30.

专利号:CN-117003926-A
优先权日:2023-08-03
标题 :Synthesis of a lubrication inhibitor and preparation of high-density solid-free low-friction drilling fluid