CAS: 619-44-3; Methyl 4-Iodobenzoate

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CAS号99768-12-4 4-甲酯基苯硼酸 | CAS号67-56-1 甲醇 | CAS号619-58-9 对碘苯甲酸 | CAS号75-18-3 二甲基硫 | CAS号1711-02-0 4-碘苯甲酰氯 | CAS号3240-34-4 碘苯二乙酸 | CAS号201230-82-2 carbon monoxide | CAS号88016-29-9 Zefirov’s reagent | CAS号4072-48-4 Iodonium, (4-ni... | CAS号115298-63-0 (4-METHOXYPHENY... | CAS号108478-29-1 4-(4-methoxy-2-... | CAS号109636-19-3 methyl 4-(11-me... | CAS号105417-32-1 methyl 4-phenyl... | CAS号53355-29-6 4-(5-甲酰基-2-呋喃基)苯甲酸甲酯 | CAS号49742-56-5 4’-甲基[1,1’-联苯]-... | CAS号33577-98-9 4-(3-羟基-3-甲基-1-... | CAS号36151-44-7 4-(2-氧代-1-吡咯烷)-苯甲酸 | CAS号5905-00-0 2,2'-Bifuran | CAS号53355-25-2 4-呋喃-2-苯甲酸甲酯 | CAS号39115-95-2 4-碘苯甲酰肼

对苯二甲酸单甲酯置于tris-(Dibenzylideneacetone)Dipalladium(0),1-碘丁烷,1,8-双二甲氨基萘,Chloro-N,N,N',N'-Bis(Tetramethylene)Formamidinium Hexafluorophosphate,4,5-双二苯基膦-9,9-二甲基氧杂蒽体系中,用 甲苯 作为反应溶剂,化学反应 16.0H,以63%的收率获得产物4-碘苯甲酸甲酯
参考文献:通过配体辅助卤化物交换实现芳基羧酸的钯催化脱羰碘化
标题:通过配体辅助卤化物交换实现芳基羧酸的钯催化脱羰碘化
摘要:我们报道了一种高效且广泛适用的钯催化碘化方法,通过原位活化酰基氯并形成鏻盐,对廉价且丰富的芳基和乙烯基羧酸进行碘化.使用 1-碘丁烷作为碘化物源,与碱和脱氧氯化试剂结合使用,可以在 Pd/xantphos 催化下获得各种芳基和乙烯基碘化物,包括复杂的药物样支架.化学计量实验和动力学分析表明了一种独特的机制,涉及 C−p 还原消除以形成 Xantphos 氯化鏻,随后通过外球亲核取代引发不寻常的卤素交换.
DOI:10.1002/anie.202103269

专利信息

专利号:US-10793495-B2
优先权日:2015-08-14
标 题:Synthesis of polyaryl substituted aryl compounds
发明人：BOULOS RAMIZ; FEUTRILL JOHN
权利人:BOULOS & COOPER PHARMACEUTICALS PTY LTD
摘要:A method for the synthesis of a aryl compound of Formula (1).n nU T-W—R 1 ) n    (1)

专利号:US-2015239796-A1
优先权日:2014-02-19
标题:One pot synthesis of 18f labeledtrifluoromethylated compounds with difluoro(iodo)methane
发明人：RüHL THOMAS; RISS PATRICK; RAFIQUE WAQAS
权利人:UNIV OSLO
摘要:The present invention relates to compositions and methods for the synthesis of 18 F labeled compounds. In particular, the present invention relates to a copper (I) mediated one pot method for 18 F-trifluoromethylation of aromatic- or heteroaromatic halides with difluoro(iodo)methane (e.g., for use at PET imaging agents).

专利号:US-9845282-B1
优先权日:2016-08-12
标题 :Palladium catalyzed synthesis of ester compounds
发明人：EL ALI BASSAM M; IBRAHIM MANSUR B; SULEIMAN RAMI K
权利人:UNIV KING FAHD PET & MINERALS
摘要:A catalytic process for synthesizing an ester compound, and a catalytic process for synthesizing an amide compound, wherein a solid-supported palladium catalyst is used to catalyze an alkoxycarbonylation reaction of an aryl halide to form the ester compound, or to catalyze an aminocarbonylation reaction of an aryl halide to form the amide compound. Various embodiments of each of the processes are also provided.

专利号:US-7579294-B2
优先权日:2004-12-29
标题:Synthesis of supported transition metal catalysts
发明人：PARK JAIWOOK; KIM NAMDU; KWON MIN SERK; PARK CHEON MIN
权利人:POSTECH FOUNDATION
摘要:A highly active and recyclable supported transition metal catalyst can be prepared by a simple process comprising mixing with heating a transition metal complex, a metal-chelating agent and an alkoxide of Ti, Al or Si, followed by treatment with water to induce a sol-gel reaction among the reactants.

专利号:US-8013157-B2
优先权日:2006-12-20
标题:Synthesis of unsaturated piperidines from piperidones with a silyl reagent
发明人：MANI NEELAKANDHA S; MORRILL CHRISTIE
权利人:JANSSEN PHARMACEUTICA NV
摘要:Syntheses of unsaturated piperidines from piperidones through a silyl piperidine reagent via the Shapiro reaction and palladium-catalyzed cross-coupling reactions with organo halides.

专利号:US-7342119-B2
优先权日:2003-09-30
标题 :Process for the synthesis of a CPLA2 inhibitor
发明人：DEHNHARDT CHRISTOPH M; MEGATI SREENIVASULU; MICHALAK RONALD S; RAVEENDRANATH PANOLIL
权利人:WYETH CORP
摘要:A process for making a substituted indole compound, including the steps of: reacting the compounds n nin a non-protic polar solvent in the presence of a catalyst to form the intermediate compoundn n nwherein Ph and X are as defined herein; and then,n nheating this intermediate compound in the solvent in the presence of the catalyst to form the substituted indole compoundn n nThe invention also includes compounds formed by this process.