CAS: 7579-36-4; Dibenzyl Oxalate

上下游产品

CAS号79-37-8 草酰氯 | CAS号100-51-6 苯甲醇 | CAS号553-90-2 草酸二甲酯 | CAS号100-44-7 氯化苄 | CAS号144-62-7 草酸 | CAS号95-92-1 草酸二乙酯 | CAS号583-52-8 草酸二钾 | CAS号3155-16-6 草酸二苯酯 | CAS号14370-71-9 Acetic acid,2-(... | CAS号538-39-6 1,2-二对甲苯基乙烷 | CAS号14310-20-4 Benzene, 1-meth... | CAS号103-29-7 1, 2-二苯乙烷 | CAS号3377-71-7 1-苄基吲哚 | CAS号35454-01-4 benzyl carbamoy... | CAS号19402-87-0 N-苄基咔唑 | CAS号100-51-6 苯甲醇

草酸,苄基二甲基(2-羟乙基)氯化铵置于尿素体系中,化学反应 2.0H,以79%的收率获得产物草酸二苄酯
参考文献:在低共熔溶剂中高效绿色酯化羧酸,无需任何其他添加剂
标题:在低共熔溶剂中高效绿色酯化羧酸,无需任何其他添加剂
摘要:摘要提出了一种羧酸与深共熔溶剂 (Des) 的季铵盐进行酯化的协议,它开辟了使用 Des 作为烷化剂,溶剂和催化剂获得酯的新途径.反应在 Des 中顺利进行,无需任何其他添加剂.取代的肉桂酸,芳香酸和脂肪酸可以以中等至非常好的收率进行酯化.该反应的优点是官能团相容性好,反应过程简单.图形概要
DOI:10.1080/00397911.2017.1390138

专利信息

专利号:US-9115128-B2
优先权日:2013-06-06
标 题 :Compounds of 3-(5-substituted Oxy-2, 4-dinitrophenyl)-2-oxo-propionic acid ester, synthesis and applications thereof
发明人：PUTHIAPARAMPIL TOM THOMAS; SAMBASIVAM GANESH; GOVINDA RAJULU GAVARA; KORAMANGALA RAVINDRA CHANDRAPPA
权利人:ANTHEM BIOSCIENCES PVT LTD; ANTHEM BIOSCIENCES PVT LTD
摘要:Synthesis of the novel compound 3 (3-(5-substituted Oxy-2,4-dinitro-phenyl)-2-oxo-propionic acid ester) to make Pyrroloquinoline quinone (PQQ) and using it for pharmaceutical purposes is described. More specifically, this disclosure relates to synthesizing the PQQ in an efficient method by using a novel intermediate Formula 1 resulting in a shorter process and higher yield of PQQ. A unique process to make sodium compound of PQQ using either sodium hydroxide and/or sodium carbonate is also shown.

专利号:US-2025115551-A1
优先权日:2023-10-03
标 题:Synthesis of ras inhibitors
发明人：LI YI; MENDOZA BENJAMIN; NAGANATHAN SRIRAM; WANG ROSS; YI YI; BALLMER STEVEN G; DAVIDSON JAMES; HUANG XIAOJUN
权利人:REVOLUTION MEDICINES INC
摘要:The present invention relates to Ras inhibitors, intermediates in the synthesis thereto, and methods for preparing the Ras inhibitors and the intermediates.

专利号:US-10266467-B2
优先权日:2017-08-02
标 题:Synthesis of glycols via transfer hydrogenation of alpha-functional esters with alcohols
发明人：CHAKRABORTY SUMIT; HEMBRE ROBERT THOMAS
权利人:EASTMAN CHEM CO
摘要:A transfer hydrogenation process for forming vicinal diols by hydrogenating 1,2-dioxygenated organic compounds using alcohols as the reducing agent instead of the traditional H 2 gas. The transfer hydrogenation is carried out under milder conditions of temperature and pressure than is typical for ester hydrogenation with H 2 . The milder conditions of operation provide benefits, such as lower operating and capital costs for industrial scale production as well as savings in product purification due to the avoidance of by-products from exposure of reaction mixtures and products to high temperatures.

专利号:US-3708477-A
优先权日:1968-06-27
标 题:Process of total synthesis of cephalosporin derivatives and intermediates
发明人：MARTEL J; HEYMES R
权利人:ROUSSEL UCLAF
摘要:PROCESS FOR THE PREPARATION OF RACEMIC OR OPTICALLYACTIVE CEPHALOSPORINE DERIVATIVES OF THE FORMULA 2,3-(-CO-N(-R1)-CH2-),7-NH2-2-CEPHEM WHEREIN R1 IS A MEMBER SELECTED FROM THE GROUP CONSISTING OF HYDROGEN, ALKYL, SUBSTITUTED AKYL, ARYL AND SUBSTITUTED ARYL, WHICH COMPRISES THE STEPS OF REACTING AN AMINO ACID OF THE FORMULA R1-NH-CH2-CH2-COOH WITH BENZYL ALCOHOL, CONDENSING THE BENZYL ESTER THUS OBTAINED WITH AN OXALATE, CONVERTING THE BENZYL ESTER OF 2,3DIOXI-4-CARBOXY-PYRROLIDINE INTO THE CORRESPONDING ACID, SUBJECTING SAID ACID TO AMINOMETHYLATION, THUS YIELDING A COMPOUND OF THE FORMULA 1-R1,3-OH,4-(R'-N(-R'')-CH2-)PYRROL-3-IN-2-ONE CONVERTING SAID COMPOUND INTO THE CORRESPONDING 4-ACYLTHIOMETHYL DERIVATIVE, CONVERTING SAID DERIVATIVE INTO THE CORRESPONDING 4-THIOMETHYL DERIVATIVE, CONDENSING SAID DERIVATIVE WITH AN ENAMINE OF THE FORMULA R-OOC-C(-Y)=CH-NH2 TO OBTAIN A THIAZINE DERIVATIVE OF THE FORMULA 2-(Y-CH(-COO-R)-),5-R1-2,3,4,5,6,7-HEXAHYDRO-PYRROLO (3,4-D)-1,3-THIAZIN-4-ONE CONVERTING SAID THIAZINE DERIVATIVE INTO A COMPOUND OF THE FORMULA 2-(H2N-CH(-COOH)-),5-R1-2,3,4,5,6,7-HEXAHYDRO-PYRROLO (3,4-)-1,3-THIAZIN-4-ONE SUBJECTING SAID COMPOUND TO THE ACTION OF A TRITYLATION AGENT, RECOVERING THE THREO ISOMER OF THE TRITYLATED DERIVATIVE, LACTAMIZING SAID THREO ISOMER TO OBTAIN THE Y-LACTAM OF DL-6H,7H-CIS-7-TRITYLAMINO-3-AMINOALKYL-CEPH 3-EME-4-CARBOXYLIC ACID, DETRITYLATING SAID Y-LACTAM AND RECOVERING SAID RACEMIC OF OPTICALLY ACTIVE CEPHALOSPORIN DERIVATIVES. THESE COMPOUNDS ARE USEFUL AS INTERMEDIATES IN THE PREPARATION OF THE CORRESPONDING 7ACYLAMINO DERIVATIVES OF THE FORMULA 2,3-(-CO-N(-R1)-CH2-),7-(R2-NH-)-2-CEPHEM WHEREIN R1 HAS THE ABOVE DEFINITION AND R2 IS THE ACYL OF AN ORGANIC CARBOXYLIC ACID WHICH COMPOUNDS ARE ALSO PART OF THE INVENTION AND ARE USEFUL AS ANTIBIOTICS.

专利号:US-2019039978-A1
优先权日:2017-08-02
标 题:Synthesis of glycols via transfer hydrogenation of alpha-functional esters with alcohols

专利号:EP-3661901-B1
优先权日:2017-08-02
标 题:Synthesis of glycols via transfer hydrogenation of alpha-functional esters with alcohols