CAS: 10300-27-3; 2-Amino-9-((2R,3R,4S,5R)-3-Hydroxy-5-(Hydroxymethyl)-4-Methoxytetrahydrofuran-2-yl)-1,9-Dihydro-6H-Purin-6-One

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118-00-3 6979-94-8 38819-10-2

上下游产品

CAS号17287-03-5 三甲基氢氧化硫,甲醇溶液 | CAS号118-00-3 鸟苷 | CAS号80791-88-4 3'-OMe-2-NH2-A | CAS号186581-53-3 重氮甲烷 | CAS号2096-10-8 2-氨基腺苷 | CAS号125132-18-5 9-((2R,3R,4S,5R...

2-氨基腺嘌呤核苷置于tin(Ll) Chloride,Adenosine Deaminase体系中,用 乙二醇二甲醚,水,二甲基亚砜,N,N-二甲基甲酰胺 用作溶剂,化学反应 74.0H,反应生成3'-甲氧基鸟苷
参考文献:Robins,Morris J.; Hansske,Fritz; Bernier,Salwa E.,Canadian Journal Of Chemistry,1981,Vol. 59,P. 3360-3364
标题:Robins,Morris J.; Hansske,Fritz; Bernier,Salwa E.,Canadian Journal Of Chemistry,1981,Vol. 59,P. 3360-3364

专利信息

专利号:WO-2025037891-A1
优先权日:2023-08-14
标题:Oligonucleotide for 5'-capped rna synthesis
发明人：KIM KYUNGJIN; KIM UK-IL; KIM DAYOUNG; CHOI KANG HYUN; KIM JI SU
权利人:ST PHARM CO LTD
摘要:The present invention relates to a novel oligonucleotide primer used for the synthesis of 5'-capped RNA. The novel oligonucleotide primer for RNA capping, represented by chemical formula 1 in the present invention, can be usefully utilized in the fields of nucleic acid therapeutic agents or vaccines.

专利号:US-7074596-B2
优先权日:2002-03-25
标 题 :Synthesis and use of anti-reverse mRNA cap analogues
发明人：DARZYNKIEWICZ EDWARD; RHOADS ROBERT E; STEPINSKI JANUSZ
权利人:UNIV LOUISIANA STATE
摘要:The ability to synthesize capped RNA transcripts in vitro has been of considerable value in a variety of applications. However, one-third to one-half of the caps have, until now, been incorporated in the reverse orientation. Such reverse caps impair the translation of in vitro-synthesized mRNAs. Novel cap analogues, such as P 1 -3′-deoxy-7-methylguanosine-5′P 3 -guanosine-5′triphosphate and P 1 -3′-O,7-dimethylguanosine-5′P 3 -guanosine-5′triphosphate, have been designed that are incapable of being incorporated into RNA in the reverse orientation. Transcripts produced with SP6 polymerase using “anti-reverseâ€? cap analogues were of the predicted length. Analysis of the transcripts indicated that reverse caps were not formed. The in vitro translational efficiency of transcripts with the novel “anti-reverseâ€? cap analogues was significantly higher than that of transcripts formed with conventional caps.

专利号:US-2006252115-A1
优先权日:2002-03-25
标题 :Synthesis and use of anti-reverse mRNA cap analogues

专利号:US-2003194759-A1
优先权日:2002-03-25
标 题 :Synthesis and use of anti-reverse mRBA cap analogues