CAS: 1074-86-8; 1H-Indole-4-Carbaldehyde

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CAS号1074-85-7 1H-吲哚-4-基甲醇 | CAS号114615-82-6 四丙基高钌酸铵 | CAS号16136-52-0 4-氰基吲哚 | CAS号112447-73-1 1-(triisopropyl... | CAS号76499-46-2 3-nitro-2-[2-(1... | CAS号39830-66-5 吲哚-4-羧酸甲酯 | CAS号3468-22-2 (1H-indol-4-yl)... | CAS号59382-59-1 2-甲基-3-硝基苯甲酸甲酯 | CAS号73816-11-2 methyl 2-[(E)-2... | CAS号83-41-0 3-硝基邻二甲苯 | CAS号49839-99-8 4-(2-硝基乙烯基)吲哚 | CAS号3468-18-6 4-(氨甲基)吲哚 | CAS号894852-86-9 1-乙基-1H-吲哚-4-甲醛 | CAS号859850-95-6 (1-甲基-1H-吲哚-4-基)甲醇 | CAS号133994-99-7 1-甲基-1H-吲哚-4-甲醛 | CAS号16096-32-5 4-甲基吲哚 | CAS号16176-73-1 2-(1H-吲哚-4-基)乙胺 | CAS号73625-11-3 1,3,4,5-四氢-N,N-... | CAS号73796-06-2 4-(1H-indol-4-y... | CAS号74059-91-9 3-[(dimethylami...

2-甲基-3-硝基苯甲酸置于palladium On Activated Charcoal Manganese(Iv) Oxide,氢气,二异丁基氢化铝,碳酸氢钠体系中,用 乙醚,二氯甲烷,N,N-二甲基甲酰胺,甲苯,苯 用作溶剂,-70.0~130.0 °C,344.73 Kpa 条件下,反应 79.5H,反应生成4-吲哚甲醛
参考文献:New Synthesis And Some Selected Reactions Of The Potential Ergot Alkaloid Precursor Indole-4-Carboxaldehyde
标题:New Synthesis And Some Selected Reactions Of The Potential Ergot Alkaloid Precursor Indole-4-Carboxaldehyde
摘要:
Doi:10.1021/jo01304A043

专利信息

专利号:US-6156889-A
优先权日:1992-04-15
标 题:Reagent useful for cleaving a protected functional group
发明人：BERNARD JEAN-MARIE; BLART ERROL; GENET JEAN-PIERRE; SAVIGNAC MONIQUE; LEMAIRE-AUDOIRE SANDRINE
权利人:RHODIA CHIMIE SA
摘要:The subject matter of the present invention relates to a reagent and a process useful for cleaving a functional group protected by an alkoxycarbonyl group during an organic synthesis. This reagent comprises: a) an aqueous phase; b) a catalyst comprising at least one group VIII element in the periodic table of elements and at least one water-soluble ligand, wherein the group VIII element in the periodic table is maintained in the aqueous phase by the formation of a complex with at least one water-soluble ligand; and c) a nucleophilic compound soluble in the aqueous phase; and optionally d) an organic phase.

专利号:US-9926293-B2
优先权日:2014-05-30
标题 :Multivalent RAS binding compounds
发明人：STOCKWELL BRENT R; WELSCH MATTHEW
权利人:UNIV COLUMBIA
摘要:The present invention provides, inter alia, compounds having the structure: n nwherein R 7 , R 8 and n are as disclosed herein, that selectively bind a RAS protein at two or more sites and methods for their synthesis. Compositions and kits containing the compounds, as well as methods of using the compounds and compositions for ameliorating or treating the effects of a disease associated with altered RAS signaling, such as a cancer, in a subject and methods for effecting cancer cell death are also provided herein. Methods of identifying a multivalent compound which binds selectively to a target protein also are provided herein.

专利号:RU-2152391-C1
优先权日:1997-01-14
标题:Derivatives of benzofuranone, method of their synthesis, medicinal and therapeutic agent

专利号:CN-116239578-B
优先权日:2022-12-08
标题 :Piperazinedione ring compound and its synthesis method and application in the preparation of anti-tumor drugs

专利号:US-6613942-B1
优先权日:1997-07-01
标题 :Glucagon antagonists/inverse agonists
发明人：LING ANTHONY; GREGOR VLAD; GONZALEZ JAVIER; HONG YUFENG; KIEL DAN; KUKI ATSUO; SHI SHENGHUA; NAERUM LARS; MADSEN PETER; SAMS CHRISTIAN; LAU JESPER; PLEWE MICHAEL BRUNO; FENG JUN; TENG MIN; JOHNSON MICHAEL DAVID; TESTON KIMBERLY ANN; SIDELMANN ULLA GROVE; KNUDSEN LOTTE BJERRE
权利人:NOVO NORDISK AS
摘要:Non-peptide compounds comprising a central hydrazide motif and methods for the synthesis thereof are disclosed. The compounds act to antagonize the action of the glucagon peptide hormone.

专利号:WO-2014016766-A1
优先权日:2012-07-25
标 题:Guanidine derivatives as trpc modulators
发明人：LINGAM V S PRASADA RAO; THOMAS ABRAHAM; DAHALE DNYANESHWAR HARISHCHANDRA; RATHI VIJAY EKNATH; KHAIRATKAR-JOSHI NEELIMA; MUKHOPADHYAY INDRANIL
权利人:GLENMARK PHARMACEUTICALS SA
摘要:The present invention is directed to guanidine derivatives as inhibitors of transient receptor potential canonical channels (TRPC channels), in particular TRPC3 and/or TRPC6 and/or TRPC7 activity, more particularly TRPC6 activity. Also provided herein are processes for preparing compounds described herein, intermediates used in their synthesis, pharmaceutical compositions thereof, and methods for treating or preventing diseases, conditions and/or disorders mediated by TRPC channels (Formula (I)).