CAS: 13139-15-6; Boc-L-Leucine

相似化合物

200936-87-4 16937-99-8 64727-35-1

上下游产品

CAS号61-90-5 L-亮氨酸 | CAS号24424-99-5 二碳酸二叔丁酯 | CAS号82010-31-9 N-B°C-L-亮氨醇 | CAS号98015-52-2 tert-butyl 1,2,... | CAS号77163-64-5 B°C-Leu-ONbn | CAS号2033-24-1 丙二酸环(亚)异丙酯 | CAS号57933-83-2 异丙烯基氯甲酸酯 | CAS号91287-28-4 L-Leucine, N-[(... | CAS号4399-40-0 苯基硫代乙内酰脲-亮氨酸 | CAS号53363-89-6 B°C-N-甲基-L-亮氨酸 | CAS号59880-97-6 酪胺盐酸盐 | CAS号33507-63-0 P物质 | CAS号57462-42-7 [Nle11]-物质P. | CAS号3350-19-4 B°C-L-亮氨酸对硝基苯酯 | CAS号32991-17-6 (S)-2-(2-((叔丁氧基... | CAS号2280-69-5 b°C-leu-met-ome | CAS号58822-25-6 [Leu5]-脑啡肽 | CAS号61-90-5 L-亮氨酸

N-叔丁氧羰基-L-亮氨醇置于sodium Bromide 2,2,6,6-Tetramethyl-Piperidine-N-Oxyl,三氯异氰尿酸,碳酸氢钠体系中,用 水,丙酮 用作溶剂,化学反应 6.0H,以92%的收率获得boc-L-亮氨酸
参考文献:Trichloroisocyanuric/tempo Oxidation Of Alcohols Under Mild Conditions: A Close Investigation
标题:Trichloroisocyanuric/tempo Oxidation Of Alcohols Under Mild Conditions: A Close Investigation
摘要:Efficient Oxidation Of Primary Alcohols To The Corresponding Carboxylic Acids Can Be Carried Out At Room Temperature And In Acetone/water,Using Trichloroisocyanuric Acid (Tcca) In The Presence Of Catalytic Tempo. The Mild Conditions Of This Procedure And The Total Absence Of Any Transition Metal Make This Reaction Suitable For Safe Laboratory Use. A Possible Mechanism Is Presented And Discussed.
Doi:10.1021/jo034276B

专利信息

专利号:WO-2024151344-A9
优先权日:2022-11-18
标题:A device that enables the combinatorial synthesis of small molecule libraries
发明人：COPELAND Gregory; LIU JANE
权利人:BRT BIOTECHNOLOGIES INC
摘要:A device for the synthesis of small molecules on a substrate is provided. The device includes a synthesis plate with vias, and a microfluidic patterning plate with a series ot open-faced channels that can be aligned with the vias on the synthesis plate. The device may be used to synthesize combinatorial libraries of small molecules.

专利号:US-5817751-A
优先权日:1994-06-23
标 题 :Method for synthesis of diketopiperazine and diketomorpholine derivatives
发明人：SZARDENINGS ANNA KATRIN; CAMPBELL DAVID
权利人:AFFYMAX TECH NV
摘要:The present invention relates to the areas of organic and medicinal chemistry. More specifically, the present invention is concerned with combinatorial and solid phase methods for the synthesis of diverse diketopiperazine derivatives, and the use of such methods to create libraries of diverse diketopiperazine derivatives. The present invention has application in the areas of chemical synthesis, the screening for new diketopiperazine derivatives having beneficial medical properties and the use of such screening to provide compositions and methods including diketopiperazine derivatives for treating disease.

专利号:US-2002019013-A1
优先权日:1999-03-08
标 题:Combined resin method for high-speed synthesis of combinatorial libraries
发明人：LOU BOLIANG; GHARBAOUI TAWFIK
摘要:A method for high-speed parallel synthesis of combinatorial libraries is disclosed where two or more resins of dissimilar functionality are combined in the same reaction vessel in which a plurality of chemical reactions are carried out to create multiple compounds which are then sequentially and individually cleaved from the different resins under the appropriate cleavage conditions for each resin. As used herein resins are considered different when they exhibit different chemical activity in the presence of cleaving or releasing agents. The resins are different when the individual resins have either dissimilar polymeric backbones or dissimilar linkers or both and thus have a different chemical activity in the presence of a release or cleaving agent from the other resins in the reaction vessel.

专利号:US-2018265547-A1
优先权日:2014-07-18
标 题 :Z-selective olefin metathesis of peptides
发明人：MANGOLD SHANE L; GRUBBS ROBERT H
权利人:CALIFORNIA INST OF TECHN
摘要:The invention relates generally to the synthesis of modified amino acids and modified peptides in the presence of cyclometalated catalysts. The invention has utility in the fields of catalysis, organic synthesis, polymer chemistry, and industrial and fine chemicals chemistry.

专利号:US-2007122842-A1
优先权日:2005-11-30
标题 :Massively parallel synthesis of proteinaceous biomolecules
发明人：RAJASEKARAN JOHN J; TIWARI GUNJAN; CABEZAS EDELMIRA; FIDANZA JACQUELINE A; SUNDARARAJAN NARAYAN
权利人:RAJASEKARAN JOHN J; TIWARI GUNJAN; CABEZAS EDELMIRA; FIDANZA JACQUELINE A; SUNDARARAJAN NARAYAN
摘要:Methods for fabricating dense arrays of polymeric molecules in a highly multiplexed manner are provided using semiconductor-processing-derived lithographic methods. Advantageously, the methods are adaptable to the synthesis of a variety of polymeric compounds. For example, arrays of peptides and polymers joined by peptide bonds may be fabricated in a highly multiplexed manner.

专利号:US-4242256-A
优先权日:1977-03-15
标 题 :Synthesis of peptide analogues
发明人：SHARPE ROBERT; SZELKE MICHAEL
权利人:SHARPE ROBERT; SZELKE MICHAEL
摘要:Compounds being analogues of a dipeptide in which the nitrogen atom of the linking amide group of the dipeptide is replaced by trivalent group ##STR1## and in which, optionally, the carbonyl function of this linking group is replaced by the divalent group --CH 2 -- are of value in the synthesis of isosterically modified peptides.