Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于氨,水体系中,化学反应生成氨基甲磺酸 参考文献:Raschig; Prahl,Justus Liebigs Annalen Der Chemie,1926,Vol. 448,P. 281 标题:Raschig; Prahl,Justus Liebigs Annalen Der Chemie,1926,Vol. 448,P. 281
专利信息
专利号:US-11629150-B2 优先权日:2016-07-01 标题:Synthesis of N-(heteroaryl)-pyrrolo[3,2-d]pyrimidin-2-amines 发明人:SMITH ALEXANDER; WHITE HANNAH S; TAVARES FRANCIS XAVIER; KRASUTSKY SERGIY; CHEN JIAN-XIE; DORROW ROBERTA L; ZHONG HUA 权利人:G1 THERAPEUTICS INC 摘要:This invention is in the area of synthesizing pyrimidine-based compounds useful in the treatment of disorders involving abnormal cellular proliferation, including but not limited to tumors and cancers.
专利号:US-5981691-A 优先权日:1997-04-23 标题 :Imide-free and mixed amide/imide thermal synthesis of polyaspartate 发明人:SIKES C STEVEN 权利人:UNIV SOUTH ALABAMA 摘要:Thermal polymerization of a salt of aspartic acid affords polyaspartate directly without hydrolyzing polysuccinimide. Copolymerization of a salt of aspartic acid with aspartic acid itself affords a copolymer of succinimide and aspartate which may be readily derivatized to produce a sulfonated, phosphonated or hydrophobized polymer.
专利号:US-4861705-A 优先权日:1983-01-31 标 题:Method for removing components of biological fluids 发明人:MARGEL SHLOMO 权利人:YEDA RES & DEV 摘要:There are provided magnetic and non-magnetic agarose and agar polyaldehyde beads with diameters ranging from 40 microns up to 1 cm, and processes for the synthesis of such beads. The polyaldehyde compounds e.g. polyacrolein, polymethacrolein or polyglutaraldehyde, were used as microspheres or as powders. The agarose-polyaldehyde beads are capable of covalently binding in a single step, through their aldehyde groups, compounds containing primary amino groups or thiol groups, such as proteins, antibodies, enzymes and drugs. The beads are useful for various biological applications e.g. affinity chromatography, hemoperfusion, ion exchange resins, cell labeling, diagnostic purposes and cell separation.
专利号:US-4761413-A 优先权日:1986-12-22 标 题:1,5-epoxy-2,3,4,5-tetrahydro-1H-3-benzazepins and use in treatment of ulcers 发明人:WACHTER MICHAEL P; KARANEWSKY DONALD S 权利人:ORTHO PHARMA CORP 摘要:The synthesis of epoxybenzazepin compounds is described. The novel compounds have anti-ulcer activity.
专利号:US-4855426-A 优先权日:1986-12-22 标题:Process of preparing 1,5-epoxy-2,3,4,5-tetrahydro-1H-3-benzazepins 发明人:WACHTER MICHAEL P; KARANEWSKY DONALD S 权利人:ORTHO PHARMA CORP 摘要:The synthesis of epoxybenzazepin compounds is described. The novel compounds have anti-ulcer activity.
专利号:US-6989401-B2 优先权日:2000-07-19 标题:Sulfonic acid derivatives of hydroxamic acids and their use as medicinal products 发明人:MAEDA KAZUHIRO; SONDA SHUJI; TAKEMOTO TADAHIRO; GOTO TOMOKAZU; KOBAYASHI FUJIO; KAJII MASAHIKO; KOMORITA NARUYASU; HIRAYAMA FUMIHIRO 权利人:MITSUBISHI PHARMA CORP 摘要:The present invention relates to a novel sulfonic acid derivative of hydroxamic acid or a pharmacologically acceptable salt thereof. More particularly, the present invention relates to a sulfonic acid derivative of hydroxamic acid or a pharmacologically acceptable salt thereof, which is useful as an inhibitor of lipopolysaccharides (LPS). In addition, the present invention relates to a novel intermediate compound useful for the synthesis of this sulfonic acid derivative of hydroxamic acid.
摘要:Schafer, E. W., Jr., W. A. Bowles Jr., and J. Hurlbut. 1983. The acute oral toxicity and repellency and hazard potential of 998 chemicals to one or more species of wild and domestic birds. Archives of Environmental Contamination and Toxicology 12:355-382. 摘要:Schafer, E.W., Jr., et al. 1976. Evaluation of 45 chemical as chemosterilants in adult male quail. Journ. of Reprod. Fertil. 48:371-375. 参考文献:10.1016/j.bbrc.2004.07.147 摘要:Ishizaki-Koizumi S, Sonaka I, Takei Y, Ikejima K, Sato N. The glycine analogue, aminomethanesulfonic acid, inhibits LPS-induced production of TNF-α in isolated rat Kupffer cells and exerts hepatoprotective effects in mice. Biochemical and Biophysical Research Communications. 2004 Sep;322(2):514–9. doi: 10.1016/j.bbrc.2004.07.147.