CAS: 146137-80-6; 2-Fluoro-4-Methylbenzaldehyde

相似化合物

7697-23-6 85070-67-3 74733-29-2

上下游产品

CAS号452-74-4 3-氟-4-溴甲苯 | CAS号95-52-3 邻氟甲苯 | CAS号201230-82-2 carbon monoxide | CAS号3030-47-5 五甲基二乙烯三胺 | CAS号352-70-5 3-氟甲苯 | CAS号50-00-0 甲醛 | CAS号452-80-2 2-氟-4-甲基苯胺 | CAS号104-87-0 对甲基苯甲醛 | CAS号68-12-2 N,N-二甲基甲酰胺 | CAS号518070-28-5 2-氟-4-甲基苯乙酸 | CAS号34879-87-3 1,6-二甲基-1H-吲唑 | CAS号82787-72-2 6-METHYL-BENZO[...

4-溴-3-氟甲苯置于bis(Triphenylphosphine)Palladium(II) Dichloride Sodium Formate体系中,用 Co,N,N-二甲基甲酰胺 用作溶剂,化学反应生成2-氟-4-甲基苯甲醛
参考文献:Process For Preparing Benzyl Alcohols And Their Use
标题:Process For Preparing Benzyl Alcohols And Their Use
摘要:苯甲醇,特别是那些在苯甲基环上带有氟代取代基或氟代烷基取代基的苯甲醇,可以通过对应的芳基溴化物进行甲酰化,形成苯甲醛,再使用进一步的甲酸酯还原苯甲醛来获得.所形成的苯甲醛不需要被分离.

专利信息

专利号:US-11702393-B2
优先权日:2020-04-21
标 题:Synthesis of a monoacylglycerol lipase inhibitor
发明人：GUERCIO GIUSEPPE
权利人:H LUNDBECK AS
摘要:Described herein is the manufacture of MAGL inhibitor 1,1,1,3,3,3-hexafluoropropan-2-yl 4-(2-(pyrrolidin-1-yl)-4-(trifluoromethyl)benzyl)piperazine-1-carboxylate including salts thereof.

专利号:US-8633182-B2
优先权日:2012-05-30
标题:Indanyloxyphenylcyclopropanecarboxylic acids
发明人：HAMPRECHT DIETER; FRATTINI SARA; LINGARD IAIN; PETERS STEFAN
权利人:HAMPRECHT DIETER; FRATTINI SARA; LINGARD IAIN; PETERS STEFAN; BOEHRINGER INGELHEIM INT
摘要:The present invention relates to compounds of general formula I, n nwherein the groups R 1 , R 2 , R 3 , m and n are defined as in claim 1 , which have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2. Furthermore, the invention relates to novel intermediates, useful for the synthesis of compounds of formula I.

专利号:US-2021323938-A1
优先权日:2020-04-21
标 题:Synthesis of a Monoacylglycerol Lipase Inhibitor

专利号:US-11801251-B2
优先权日:2015-11-03
标 题 :Selective HDAC8 inhibitors and their uses
发明人：MEYER-ALMES FRANZ-JOSEF; MEYNERS CHRISTIAN; KLEINSCHEK ALEXANDER; HAUS PATRICIA
权利人:HOCHSCHULE DARMSTADT
摘要:The present invention relates to small molecule compounds based on benzopyrimido- or benzoimidazo-thiazin-imine as well as their (synthesis) intermediates and their use as HDAC inhibitors, in particular HDAC8 inhibitors. The present invention also relates to the use of said compounds in the treatment of cancer and as therapeutic agents for eukaryotic parasites and respective methods of treatment.