CAS: 19522-67-9; N1-Isopropylethane-1,2-Diamine

相似化合物

320580-88-9 4013-94-9 4062-60-6

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CAS号107-15-3 乙二胺 | CAS号67-63-0 异丙醇 | CAS号67-64-1 丙酮 | CAS号2576-47-8 2-溴乙胺氢溴酸盐 | CAS号75-31-0 异丙胺 | CAS号64-17-5 乙醇 | CAS号75-26-3 2-溴丙烷 | CAS号16728-80-6 2-(异丙基氨基)乙腈 | CAS号21921-33-5 1-异丙基咪唑啉-2-酮 | CAS号636-70-4 三乙胺氢溴酸盐 | CAS号7550-35-8 溴化锂 | CAS号124-40-3 二甲胺 | CAS号81327-55-1 1,6,11,16-tetra... | CAS号320580-88-9 N-B°C-2-异丙胺基乙胺 | CAS号20406-60-4 咪匹马唑 | CAS号85694-52-6 1,2,5-Thiadiazo... | CAS号84606-45-1 1-异丙基-2-甲基咪唑

2-(异丙基氨基)乙基氨基甲酸叔丁酯置于盐酸体系中,用 乙酸乙酯 用作溶剂,化学反应生成N-异丙基乙二胺
参考文献:催化不对称分子间亚酰胺化-亲核加成-内酰胺化反应高对映选择性合成2,3-二氢-1 H-咪唑并[2,1-A ] Isoindol-5(9B H)-Ones
标题:催化不对称分子间亚酰胺化-亲核加成-内酰胺化反应高对映选择性合成2,3-二氢-1 H-咪唑并[2,1-A ] Isoindol-5(9B H)-Ones
摘要:手性磷酸催化n 1-烷基乙烷-1,2-二胺与2-甲酰基苯甲酸甲酯的高对映选择性催化不对称分子内级联酰亚胺化-亲核加成-内酰胺化是制备具有医学意义的手性2,3-手性化合物的第一种有效方法二氢-1 H-咪唑并[2,1-A ] Isoindol-5(9B H)-具有高收率和优异的对映选择性.已经显示出该策略对于各种2-甲酰基苯甲酸甲酯是相当普遍的.
Doi:10.1021/ol5031603

专利信息

专利号:US-11008358-B2
优先权日:2015-03-25
标题:Synthesis of desosamines
发明人：MYERS ANDREW G; ZHANG ZIYANG
权利人:HARVARD COLLEGE
摘要:The present invention provides desosamine and mycaminose analogs and nitro sugars and methods for their preparation. The invention also provides methods of cyclizing a compound of Formula (A′) with glyoxal to give a nitro sugar of Formula (B). Methods for the preparation of compound of Formula (D′) are provided comprising cyclization of a nitro alcohol to give a nitro sugar and reduction and alkylation of the nitro sugar to give a desosamine, mycaminose, or an analog thereof.

专利号:US-12303865-B2
优先权日:2022-10-10
标 题 :Aqueous manufacture of aminated MOF complexes
发明人：GOSSELIN AERI; GAMORAS JOEL H; HERM ZOEY ROSE; MCDONALD THOMAS M; WENZ GRAHAM B; ZHU LINA
权利人:MOSAIC MAT INC
摘要:This disclosure relates to a select class of porous adsorbent, metal-organic frameworks (MOFs) capable of adsorbing carbon dioxide, their manufacturing, applications, and methods of use. Specifically, this disclosure relates to the solvo(hydro)thermal synthesis of a family of metal-organic frameworks, and their subsequent processing and transformation into material forms suitable for use in acid gas separations. More specifically, this disclosure relates to the preparation and recovery of MOFs at multiple scales of production, demonstrating the suitability and robustness of the materials thus obtained by the disclosed synthetic route and post-synthetic manipulation employed to tailor the materials for use in a variety of commercial acid gas separation systems, with improved performances, recyclability, and reuse characteristics.

专利号:US-4894380-A
优先权日:1987-04-03
标题:2-mercapto-5-pyridyl-1,3,4-oxadiazoles and 2-mercapto-5-pyridyl-1,3,4-thiadiazoles of the formula I
发明人：NYFELER ROBERT; ECKHARDT WOLFGANG; BERIGER ERNST; KRISTIANSEN ODD
权利人:CIBA GEIGY CORP
摘要:The invention relates to 2-mercapto-5-pyridyl-1,3,4-oxadiazoles and 2-mercapto-5-pyridyl-1,3,4-thiadiazoles of the formula I (I) wherein X is oxygen or sulfur, R' is C1-C3alkyl which is substituted by bromine, fluorine, C1-C3alkoxy or cyano; unsubstituted or halogen-substituted C3-C7alkenyl; unsubstituted or halogen-substituted C4-C7alkynyl, R is C1-C3alkyl, unsubstituted C1-C3alkoxy or C1-C3alkoxy which is substituted by halogen or C1-C3alkoxy; unsubstituted or halogen-substituted C3-C7alkenyl; C3-C7alkynyl, C1-C3alkylthio, halogen, cyano, hydroxy, amino or amino which is substituted by one or two C1-C3alkyl groups; or is aminocarbonyl; and n is 0, 1, 2, 3 or 4, to the preparation of the compounds of formula I and to novel intermediates for the synthesis of these compounds. The compounds of formula I have nematicidal properties. The invention further relates to nematicidal compositions which contain at least one compound of formula I as active component, and to methods of using said compounds and of the compositions containing them for controlling nematodes.

专利号:US-2009111737-A1
优先权日:1999-05-24
标题:Novel antibacterial agents
发明人：CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
权利人:CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
摘要:This invention relates to novel multibinding compounds (agents) that are antibacterial agents. The multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands in their monovalent (i.e., unlinked) state have the ability to bind to a an enzyme involved in cell wall biosynthesis and metabolism, a precursor used in the synthesis of the bacterial cell wall and/or the bacterial cell surface thereby interfere with the synthesis and/or metabolism of the cell wall. In particular the multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands hasn a ligand domain capable of binding to penicillin binding proteins, a transpeptidase enzyme, a substrate of a transpeptidase enzyme, a beta-lactamase enzyme, pencillinase enzyme, cephalosporinase enzyme, a transglycoslase enzyme, or a transglycosylase enzyme substrate; Preferably, the ligands are selected from the beta lactam or glycopeptide class of antibacterial agents.

专利号:US-2013102730-A1
优先权日:2010-04-02
标 题:Polyamine-containing polymers and methods of synthesis and use
发明人：JOST ROBERT W; ULUDAG HASAN; BOLUK MEHMET YAMAN
权利人:JOST ROBERT W; ULUDAG HASAN; BOLUK MEHMET YAMAN; ALBERTA INNOVATES TECHNOLOGY FUTURES
摘要:The present invention relates to polyamine-containing polymers and methods of their synthesis and use. The polymer may be hydroxyethylcellulose, dextran, poly(vinyl alcohol) or poly(methyl acrylate).

专利号:US-2024279231-A1
优先权日:2021-05-20
标题:Map4k4 inhibitors and methods of synthesis and use thereof
发明人：AWASTHI VIBHUDUTTA; EEDA VENKATESWARARAO
权利人:UNIV OKLAHOMA
摘要:The compound DMX-5804, IUPAC name 5-(4-(2-methoxyethoxy)phenyl)-7-phenyl-3,4a,7,7a-tetrahydro-4H-pyrrolo[2,3-d]pyrimidin-4-one, is a potent and selective inhibitor of mitogen-activated protein kinase kinase kinase kinase-4 (MAP4K4). The present disclosure describes a scalable and practical synthesis process for making DMX-5804. The process (1) doesn't rely on transition metals, (2) has reduced duration of reactions, (3) is streamlined with significantly improved yields using low cost raw materials, (4) includes no microwave-assisted reactions, (5) does not require column purification, and (6) generally results in crystalized products having over a 95% purity in each step. The present disclosure also describes DMX-5804 analogs and derivatives for use in inhibiting MAP4K4, and scalable and practical processes for making such DMX-5804 analogs.